Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Skeletal muscle protein structural dynamics and function drive applications to drug discovery
Thomas, D. D. (PI), Cornea, R. L. (CoI), Lowe, D. A. (CoI) & Rebbeck, R. T. (Co-Principal Investigator)
NIH NIAMS NATL INST OF ARTHRIT
5/1/23 → 4/30/28
Project: Research project
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The NKA-FXYD interactome in Health and Disease
Rebbeck, R. T. (PI) & Cornea, R. L. (Prior Principal Investigator)
LOYOLA UNIVERSITY OF CHICAGO, NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
4/1/22 → 3/31/26
Project: Research project
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Structural Dynamics of Muscle Calcium ATPase Regulation
Thomas, D. D. (PI), Aihara, H. (CoI), Cornea, R. L. (Co-Principal Investigator) & Aldrich, C. (Consultant/Collaborator)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/1/20 → 4/30/24
Project: Research project
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Development of a Mirror-Image Natural Product as an Antiarrhythmic Therapeutic
Rebbeck, R. T. (PI) & Cornea, R. L. (Prior Principal Investigator)
VANDERBILT UNIVERSITY, NATIONAL INSTITUTES OF HEALTH (NIH)
3/17/20 → 2/28/24
Project: Research project
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High-Throughput Screens to Discover Novel Modulators of Dysfunctional RyR1 Channels for Therapeutic Development
Cornea, R. L. (PI)
1/23/20 → 7/7/22
Project: Research project
Research output
- 60 Article
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ent-Verticilide B1 Inhibits Type 2 Ryanodine Receptor Channels and is Antiarrhythmic in Casq2-/- MiceS
Gochman, A., Do, T. Q., Kim, K., Schwarz, J. A., Thorpe, M. P., Blackwell, D. J., Ritschel, P. A., Smith, A. N., Rebbeck, R. T., Akers, W. S., Cornea, R. L., Laver, D. R., Johnston, J. N. & Knollmann, B. C., Mar 1 2024, In: Molecular Pharmacology. 105, 3, p. 194-201 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors
Rebbeck, R. T., Svensson, B., Zhang, J., Samsó, M., Thomas, D. D., Bers, D. M. & Cornea, R. L., Dec 2024, In: Nature communications. 15, 1, 5120.Research output: Contribution to journal › Article › peer-review
Open Access -
Advancements in a FRET Biosensor for Live-Cell Fluorescence-Lifetime High-Throughput Screening of Alpha-Synuclein
Braun, A. R., Kochen, N. N., Yuen, S. L., Liao, E. E., Cornea, R. L., Thomas, D. D. & Sachs, J. N., Jan 1 2023, In: ASN Neuro. 15Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Fluorescence lifetime FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulators
Roopnarine, O., Yuen, S. L., Thompson, A. R., Roelike, L. N., Rebbeck, R. T., Bidwell, P. A., Aldrich, C. C., Cornea, R. L. & Thomas, D. D., Dec 2023, In: Scientific reports. 13, 1, 10673.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Interaction of DWORF with SERCA and PLB as determined by EPR spectroscopy
Rustad, M. D., Roopnarine, O., Cornea, R. L. & Thomas, D. D., Feb 19 2023, In: Biochemical and Biophysical Research Communications. 645, p. 97-102 6 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations
Datasets
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Ensembles from dynamic refinement of non-phosphorylated and phosphorylated phospholamban-SERCA complex
Weber, D. K., Sanz-Hernández, M., Uddigiri, V. R., Wang, S., Larsen, E., Tata, G., Gustavsson, M., Cornea, R. L., Thomas, D. D., De Simone, A. & Veglia, G., Data Repository for the University of Minnesota, 2021
DOI: 10.13020/bkja-jq93, http://hdl.handle.net/11299/218010
Dataset