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Research Output 1978 2019

1978
15 Citations (Scopus)

Differences in incorporation of nucleic acid bases and nucleosides by various Mycoplasma and Acholeplasma species

McIvor, R. S. & Kenny, G. E., Dec 1 1978, In : Journal of Bacteriology. 135, 2, p. 483-489 7 p.

Research output: Contribution to journalArticle

Acholeplasma
Nucleic Acid Precursors
Acholeplasma laidlawii
Mycoplasma pneumoniae
Thymine
1980
102 Citations (Scopus)

Facilitated transport of uracil and 5‐fluorouracil, and permeation of orotic acid into cultured mammalian cells

Wohlhueter, R. M., Mc Ivor, R. S. & Plagemann, P. G. W., Jan 1 1980, In : Journal of Cellular Physiology. 104, 3, p. 309-319 11 p.

Research output: Contribution to journalArticle

Orotic Acid
Uracil
Permeation
Cultured Cells
Nucleotides
1982
5 Citations (Scopus)

An improved enzymatic radioassay for ribose 1-phosphate

Mc Ivor, R. S., Wohlhueter, R. M. & Plagemann, P. G. W., Nov 15 1982, In : Analytical Biochemistry. 127, 1, p. 150-154 5 p.

Research output: Contribution to journalArticle

Cell Extracts
Purine-Nucleoside Phosphorylase
Paper Chromatography
Inosine
Hypoxanthine
1983
16 Citations (Scopus)

Uracil phosphoribosyltransferase from Acholeplasma laidlawii: Partial purification and kinetic properties

Mc Ivor, R. S., Wohlhueter, R. M. & Plagemann, P. G. W., Dec 1 1983, In : Journal of Bacteriology. 156, 1, p. 192-197 6 p.

Research output: Contribution to journalArticle

uracil phosphoribosyltransferase
Acholeplasma laidlawii
Uracil
Ribs
Chromatography
4 Citations (Scopus)

Uridine phosphorylase from Acholeplasma laidlawii: Purification and kinetic properties

Mc Ivor, R. S., Wohlhueter, R. M. & Plagemann, P. G. W., Dec 1 1983, In : Journal of Bacteriology. 156, 1, p. 198-204 7 p.

Research output: Contribution to journalArticle

Uridine Phosphorylase
Acholeplasma laidlawii
Uridine
Uridine Kinase
Uracil
1984
36 Citations (Scopus)

Cloning of human adenosine deaminase cDNA and expression in mouse cells

Valeric, D., Mc Ivor, R. S., Williams, S. R., Duyvesteyn, M. G. C., van Ormondt, H., van der Eb, A. J. & Martin, D. W., Jan 1 1984, In : Gene. 31, 1-3, p. 147-153 7 p.

Research output: Contribution to journalArticle

Adenosine Deaminase
Organism Cloning
Plasmids
Complementary DNA
Metallothionein
1985
19 Citations (Scopus)

Expression of a cDNA sequence encoding human purine nucleoside phosphorylase in rodent and human cells

McIvor, R. S., Goddard, J. M., Simonsen, C. C. & Martin, D. W., Jan 1 1985, In : Molecular and Cellular Biology. 5, 6, p. 1349-1357 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Mammalian Expression of Cloned cDNA Sequences Encoding Human Purine Nucleoside Phosphorylase and Adenosine Deaminase

McIVOR, R. SCOTT., VALERIO, DINKO., WILLIAMS, STEVEN. R., GODDARD, JUDY. M., SIMONSEN, CHRISTIAN. C., DUYVESTEYN, MARJA. G. C., VAN ORMONDT, HANS., VAN DER EB, ALEX. J. & MARTIN, DAVID. W., Jan 1 1985, In : Annals of the New York Academy of Sciences. 451, 1, p. 245-249 5 p.

Research output: Contribution to journalArticle

Pentosyltransferases
Nucleoside Deaminases
Purine-Nucleoside Phosphorylase
Genetic Code
Adenosine Deaminase
19 Citations (Scopus)

Uridine phosphorylase from Novikoff rat hepatoma cells: Purification, kinetic properties, and its role in uracil anabolism

Mc Ivor, R. S., Wohlhueter, R. M. & Plagemann, P. P. G., Jan 1 1985, In : Journal of Cellular Physiology. 122, 3, p. 397-404 8 p.

Research output: Contribution to journalArticle

Uridine Phosphorylase
Experimental Liver Neoplasms
Uracil
Purification
Rats
1986

Molecular basis of a human purine nucleoside phosphorylase deficiency

Williams, S. R., McIvor, R. S. & Martin, D. W., Dec 1 1986, In : Cold Spring Harbor Symposia on Quantitative Biology. 51, 2, p. 1059-1064 6 p.

Research output: Contribution to journalArticle

phosphorylase
structural genes
nucleosides
purines
amino acid sequences
1987
37 Citations (Scopus)

A human purine nucleoside phosphorylase deficiency caused by a single base change

Williams, S. R., Gekeler, V., McIvor, R. S. & Martin, D. W., Jan 1 1987, In : Journal of Biological Chemistry. 262, 5, p. 2332-2338 7 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Genes
Exons
Mutation
Gels
53 Citations (Scopus)

Human purine nucleoside phosphorylase and adenosine deaminase: Gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses

McIvor, R. S., Johnson, M. J., Miller, A. D., Pitts, S., Williams, S. R., Valerio, D., Martin, D. W. & Verma, I. M., Jan 1 1987, In : Molecular and Cellular Biology. 7, 2, p. 838-846 9 p.

Research output: Contribution to journalArticle

Pentosyltransferases
Nucleoside Deaminases
Purine-Nucleoside Phosphorylase
Adenosine Deaminase
Genetic Engineering
1990
11 Citations (Scopus)
Moloney murine leukemia virus
Metallothionein
Proviruses
Purine-Nucleoside Phosphorylase
Genes
45 Citations (Scopus)

Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells

McIvor, R. S. & Simonsen, C. C., Dec 1 1990, In : Nucleic acids research. 18, 23, p. 7025-7032 8 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Methotrexate
Complementary DNA
Enzymes
Codon
1991
7 Citations (Scopus)

Herpes simplex virus thymidine kinase enzymatic assay in transient transfection experiments using thymidine kinase-deficient cells

Jonsson, J. J. & Mc Ivor, R. S., Jan 1 1991, In : Analytical Biochemistry. 199, 2, p. 232-237 6 p.

Research output: Contribution to journalArticle

Chloramphenicol O-Acetyltransferase
Thymidine Kinase
Human Herpesvirus 1
Enzyme Assays
Simplexvirus
11 Citations (Scopus)

Sequence and functional characterization of the human purine nucleoside phosphorylase promoter

Jonsson, J. J., Williams, S. R. & McIvor, R. S., Jan 1 1991, In : Nucleic acids research. 19, 18, p. 5015-5020 6 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Chloramphenicol O-Acetyltransferase
GC Rich Sequence
5' Flanking Region
Genetic Promoter Regions
1992
2 Citations (Scopus)

Assay for expression of methotrexate-resistant dihydrofolate reductase activity in the presence of drug-sensitive enzyme

Thompson, K., Vinh, D. B. N. & Mc Ivor, R. S., Jan 1 1992, In : Journal of Pharmacological and Toxicological Methods. 28, 3, p. 167-173 7 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Methotrexate
Assays
Enzymes
Pharmaceutical Preparations
8 Citations (Scopus)
Purine-Nucleoside Phosphorylase
T-Cell Lymphoma
Genetic Therapy
T-Lymphocytes
Genes
2 Citations (Scopus)
GM2 Gangliosidosis
Hexosaminidases
DNA Sequence Analysis
Alleles
Mutation
68 Citations (Scopus)

Intron requirement for expression of the human purine nucleoside phosphorylase gene

Jonsson, J. J., Foresman, M. D., Wilson, N. & Mc Ivor, R. S., Jun 25 1992, In : Nucleic acids research. 20, 12, p. 3191-3198 8 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Introns
Genes
Acetyltransferases
Isoenzymes
3 Citations (Scopus)

Isolation and expression of a murine purine phosphorylase-encoding cDNA and sequence similarity with the human message

Nelson, D. M., Foresman, M. D., Ronnei, B. J. & Mc Ivor, R. S., Apr 15 1992, In : Gene. 113, 2, p. 215-221 7 p.

Research output: Contribution to journalArticle

Phosphorylases
Complementary DNA
Clone Cells
Purine-Nucleoside Phosphorylase
Moloney murine leukemia virus
1993
12 Citations (Scopus)
Casein Kinase II
Cloning
Androgens
Rats
Organism Cloning
42 Citations (Scopus)
Iduronate Sulfatase
Mucopolysaccharidosis II
Gene Expression
Cell Line
Enzymes
7 Citations (Scopus)
Interleukin-3
Genes
Bone Marrow
SEKDEL sequence
Terminal Repeat Sequences
12 Citations (Scopus)
Tetrahydrofolate Dehydrogenase
Retroviridae
Methotrexate
Viruses
Bone Marrow
1994
9 Citations (Scopus)

An enhancer in the first intron of the human purine nucleoside phosphorylase-encoding gene

Jonsson, J. J., Converse, A. & Mclvor, R. S., Mar 25 1994, In : Gene. 140, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Introns
Genes
Thymidine Kinase
Cats
41 Citations (Scopus)
Neuroblastoma
Interleukin-2
Immunity
Genes
Neoplasms

Minutes of the Human Gene Therapy Subcommittee meeting, November 21-22, 1991

Walters, LR., Areen, J., Brewer, M. F., Capron, A., Childress, J. F., Epstein, C. J., Erickson, R. P., Gellert, M. F., Kelley, W. N., Leventhal, B. G., McIvor, R. S., Meyers, A. S., Miller, D. A., Murray, R. F., Neiman, P. E., Parkman, R., Zallen, D. T., Wivel, N. A. & Sindelar, A., Dec 1 1994, In : Human Gene Therapy. 5, 2, p. 229-262 34 p.

Research output: Contribution to journalArticle

Genetic Therapy
34 Citations (Scopus)
Mutagenesis
Tetrahydrofolate Dehydrogenase
Amino Acid Substitution
Methotrexate
Codon
18 Citations (Scopus)
Cell Adhesion Molecules
Intercellular Adhesion Molecule-1
Neuroblastoma
Transfection
Genes
1995
14 Citations (Scopus)

Correction of proliferative responses in purine nucleoside phosphorylase (PNP)-deficient T lymphocytes by retroviral-mediated PNP gene transfer and expression

Nelson, D. M., Butters, K. A., Markert, M. L., Reinsmoen, N. L. & Mc Ivor, R. S., Mar 21 1995, In : Journal of Immunology. 154, 6, p. 3006-3014 9 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
T-Lymphocytes
Gene Expression
Moloney murine leukemia virus
Terminal Repeat Sequences
30 Citations (Scopus)

Dependency on intercellular adhesion molecule recognition and local interleukin-2 provision in generation of an in vivo CD8+ T-cell immune response to murine myeloid leukemia

Boyer, M. W., Orchard, P. J., Gorden, K. B., Anderson, P. M., McIvor, R. S. & Blazar, B. R., Jan 1 1995, In : Blood. 85, 9, p. 2498-2506 9 p.

Research output: Contribution to journalArticle

Myeloid Leukemia
T-cells
Cell Adhesion Molecules
Interleukin-2
Leukemia
2 Citations (Scopus)
Granulocyte-Macrophage Colony-Stimulating Factor
Endoplasmic Reticulum
Simian virus 40
Clone Cells
Genes
29 Citations (Scopus)

Identification of a cDNA encoding tubulointerstitial nephritis antigen

Nelson, T. R., Charonis, A. S., Mc Ivor, R. S. & Butkowski, R. J., Jan 1 1995, In : Journal of Biological Chemistry. 270, 27, p. 16265-16270 6 p.

Research output: Contribution to journalArticle

Interstitial Nephritis
Complementary DNA
Antigens
Amino Acid Sequence
Amino Acids
60 Citations (Scopus)

Protection of mice from lethal doses of methotrexate by transplantation with transgenic marrow expressing drug-resistant dihydrofolate reductase activity

May, C., Gunther, R. & Mc Ivor, R. S., Jan 1 1995, In : Blood. 86, 6, p. 2439-2448 10 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Methotrexate
Transplantation
Bone Marrow
Animals
20 Citations (Scopus)

Retrovirus-Mediated Transduction of an Engineered Intron-Containing Purine Nucleoside Phosphorylase Gene

Jonsson, J. J., Habel, D. E. & Mc Ivor, R. S., May 1 1995, In : Human Gene Therapy. 6, 5, p. 611-623 13 p.

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Retroviridae
Introns
Genes
RNA Splice Sites
1996
11 Citations (Scopus)

Comparative methotrexate resistance of transgenic mice expressing two distinct dihydrofolate reductase variants

Morris, J. A., May, C., Kim, H. S., Ismail, R., Wagner, J. E., Gunther, R. & Mc Ivor, R. S., Jan 1 1996, In : Transgenics. 2, 1, p. 53-67 15 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Methotrexate
Genetic Therapy
Transgenic Mice
Gene Expression
13 Citations (Scopus)
Tetrahydrofolate Dehydrogenase
Methotrexate
Pharmaceutical Preparations
Therapeutics
Mutagenesis
1 Citation (Scopus)
Interleukin-2
Lymphoma
Neoplasms
Clone Cells
Vaccination
7 Citations (Scopus)
Tetrahydrofolate Dehydrogenase
Methotrexate
Transgenic Mice
Bone Marrow
Pharmaceutical Preparations
6 Citations (Scopus)

Methotrexate resistance of mouse dihydrofolate reductase: Effect of substitution of phenylalanine-31 by serine or tryptophan

Evenson, D. A., Adams, J., McIvor, R. S. & Wagner, C. R., Apr 26 1996, In : Journal of Medicinal Chemistry. 39, 9, p. 1763-1766 4 p.

Research output: Contribution to journalReview article

Tetrahydrofolate Dehydrogenase
Phenylalanine
Methotrexate
Tryptophan
Serine
29 Citations (Scopus)

Preclinical studies of lymphocyte gene therapy for mild Hunter syndrome (mucopolysaccharidosis type II)

Braun, S. E., Pan, D., Aronovich, E. L., Jonsson, J. J., Mc Ivor, R. S. & Whitley, C. B., Feb 10 1996, In : Human Gene Therapy. 7, 3, p. 283-290 8 p.

Research output: Contribution to journalArticle

Iduronate Sulfatase
Mucopolysaccharidosis II
Genetic Therapy
Lymphocytes
Retroviridae
1997
54 Citations (Scopus)

Gene therapy for chronic myelogenous leukemia (CML): A retroviral vector that renders hematopoietic progenitors methotrexate-resistant and CML progenitors functionally normal and nontumorigenic in vivo

Zhao, R. C. H., McIvor, R. S., Griffin, J. D. & Verfaillie, C. M., Dec 15 1997, In : Blood. 90, 12, p. 4687-4698 12 p.

Research output: Contribution to journalArticle

Gene therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methotrexate
Genetic Therapy
Genes
23 Citations (Scopus)

Transgenic mice expressing the tyr22 variant of murine DHFR: Protection of transgenic marrow transplant recipients from lethal doses of methotrexate

James, R. I., May, C., Vagt, M. D., Studebaker, R. & Mc Ivor, R. S., Dec 9 1997, In : Experimental Hematology. 25, 12, p. 1286-1295 10 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Methotrexate
Transgenic Mice
Bone Marrow
Transgenes
1998

Gene therapy for chronic myelogenous leukemia

Verfaillie, C. M., Zhao, R. C. & Mc Ivor, R. S., Jan 1 1998, In : Hematology and Cell Therapy. 40, 5, 1 p.

Research output: Contribution to journalArticle

Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Genetic Therapy
13 Citations (Scopus)

Methotrexate-resistant form of dihydrofolate reductase protects transgenic murine embryos from teratogenic effects of methotrexate

Sutton, C., Mc Ivor, R. S., Vagt, M., Doggett, B. & Kapur, R. P., Jan 1 1998, In : Pediatric and Developmental Pathology. 1, 6, p. 503-512 10 p.

Research output: Contribution to journalArticle

Tetrahydrofolate Dehydrogenase
Methotrexate
Embryonic Structures
Transgenes
Fetal Diseases

Recombinant DNA Advisory Committee Meeting, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, March 10 1998: Department of Health and Human Services - National Institutes of Health

Mickelson, C. A., Gordon, J. W., Markert, M. L., Greenblatt, J. J., McIvor, R. S., Aguilar-Codova, C. E., Kumar, R., Tufaro, F., Osborne, S., Skirboll, Macklin, R., Fost, Lantos & Taylor, A., Nov 1 1998, In : Human Gene Therapy. 9, 16, p. 2427-2454 28 p.

Research output: Contribution to journalArticle

Regulatory issues. Recombinant DNA advisory committee, department of health and human services, national institutes of health. Minutes of meeting December 15-16, 1997

Aguilar-Cordova, C. E., Ando, D. G., Gordon, J. W., Greenblatt, J. J., Lai, M. M. C., Leinwand, L. A., Lysaught, M. T., Macklin, R., Markert, M. L., Mc Ivor, R. S., Mickelson, C. A., Rothenberg, K., Verma, I. M., Wolff, J. A., Knorr, D. W., Dommel, J., Jones, D. D. & Noguchi, P., Jul 20 1998, In : Human Gene Therapy. 9, 11, p. 1643-1684 42 p.

Research output: Contribution to journalArticle

1999
15 Citations (Scopus)
Iduronidase
Mucopolysaccharidosis I
Dependovirus
Fibroblasts
Genes
10 Citations (Scopus)

Gene therapy of genetic diseases and cancer

Mc Ivor, R. S., Dec 15 1999, In : Pediatric Transplantation. 3, SUPPL. 1, p. 116-121 6 p.

Research output: Contribution to journalArticle

Inborn Genetic Diseases
Genetic Therapy
Neoplasms
Genes
Hematopoietic Stem Cells