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  • 3 Similar Profiles
Kidney Medicine & Life Sciences
Hepatocyte Nuclear Factor 1-beta Medicine & Life Sciences
Polycystic Kidney Diseases Medicine & Life Sciences
Cysts Medicine & Life Sciences
Genes Medicine & Life Sciences
Cilia Medicine & Life Sciences
Epithelial Cells Medicine & Life Sciences
Cystic Kidney Diseases Medicine & Life Sciences

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Projects 2015 2021

kidneys
gene expression
kidneys
gene expression

Research Output 1983 2018

Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria

Wong, D. W. L., Yiu, W. H., Chan, K. W., Li, Y., Li, B., Lok, S. W. Y., Taketo, M. M., Igarashi, P., Chan, L. Y. Y., Leung, J. C. K., Lai, K. N. & Tang, S. C. W. Jun 1 2018 In : Kidney international. 93, 6, p. 1367-1383 17 p.

Research output: Contribution to journalArticle

beta Catenin
Proteinuria
Inflammation
Kidney
Blood Urea Nitrogen

Adenylyl cyclase 5 deficiency reduces renal cyclic AMP and cyst growth in an orthologous mouse model of polycystic kidney disease

Wang, Q., Cobo-Stark, P., Patel, V., Somlo, S., Han, P. L. & Igarashi, P. Feb 1 2018 In : Kidney international. 93, 2, p. 375-389 15 p.

Research output: Contribution to journalArticle

Polycystic Kidney Diseases
Cyclic AMP
Cysts
Kidney
Growth

Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling

Aboudehen, K., Farahani, S., Kanchwala, M., Chan, S. C., Avdulov, S., Mickelson, A., Lee, D., Gearhart, M. D., Patel, V., Xing, C. & Igarashi, P. Jan 1 2018 In : Journal of Biological Chemistry. 293, 24, p. 9388-9398 11 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
Autosomal Dominant Polycystic Kidney
Cystic Kidney Diseases
Kidney
Respiration

New insights into the role of HNF-1β in kidney (patho)physiology

Ferrè, S. & Igarashi, P. Jul 1 2018 (Accepted/In press) In : Pediatric Nephrology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Hepatocyte Nuclear Factor 1-beta
Kidney
Nephrons
Zyxin
Multicystic Dysplastic Kidney
2 Citations

Hepatocyte nuclear factor-1β regulates urinary concentration and response to hypertonicity

Aboudehen, K., Noureddine, L., Cobo-Stark, P., Avdulov, S., Farahani, S., Gearhart, M. D., Bichet, D. G., Pontoglio, M., Patel, V. & Igarashi, P. Oct 1 2017 In : Journal of the American Society of Nephrology. 28, 10, p. 2887-2900 14 p.

Research output: Contribution to journalArticle

Hepatocyte Nuclear Factor 1-beta
Kidney
Aquaporins
Transcription Factors
Kidney Tubules