Peng Liu

20062019
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Research Output 2006 2019

2019
Open Access
Staphylococcal Protein A
Artifacts
Brain
Western Blotting
Antibodies

A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients

Liu, P., Smith, B., Huang, E. S., Mahesh, A., Vonsattel, J. P. G., Petersen, A. J., Gomez-Pastor, R. & Ashe, K. H., Jul 30 2019, In : Acta Neuropathologica Communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Caspase 2
Huntington Disease
Brain Diseases
Neurodegenerative Diseases
Trinucleotide Repeat Expansion

Human cerebrospinal fluid 6E10- immunoreactive protein species contain amyloid precursor protein fragments

Grant, M. K. O., Handoko, M., Rozga, M., Brinkmalm, G., Portelius, E., Blennow, K., Ashe, K. H., Zahs, K. R. & Liu, P., Feb 1 2019, In : PloS one. 14, 2, e0212815.

Research output: Contribution to journalArticle

Open Access
Cerebrospinal fluid
Amyloid beta-Protein Precursor
cerebrospinal fluid
amyloid
Cerebrospinal Fluid
2017
2 Citations (Scopus)

Quantitative Comparison of Dense-Core Amyloid Plaque Accumulation in Amyloid-β Protein Precursor Transgenic Mice

Liu, P., Reichl, J. H., Rao, E. R., McNellis, B. M., Huang, E. S., Hemmy, L. S., Forster, C. L., Kuskowski, M. A., Borchelt, D. R., Vassar, R., Ashe, K. H. & Zahs, K. R., Jan 1 2017, In : Journal of Alzheimer's Disease. 56, 2, p. 743-761 19 p.

Research output: Contribution to journalArticle

Open Access
Amyloid beta-Protein Precursor
Amyloid Plaques
Transgenic Mice
Alzheimer Disease
Amyloidosis
2015
12 Citations (Scopus)

Characterization of a novel mouse model of Alzheimer's disease - Amyloid pathology and unique β-amyloid oligomer profile

Liu, P., Paulson, J. B., Forster, C. L., Shapiro, S. L., Ashe, K. H. & Zahs, K. R., May 6 2015, In : PLoS One. 10, 5, e0126317.

Research output: Contribution to journalArticle

Pathology
amyloid
Alzheimer disease
Tetracycline
Oligomers
1 Citation (Scopus)

Enzymatic characterization of recombinant food vacuole plasmepsin 4 from the rodent malaria parasite plasmodium berghei

Liu, P., Robbins, A. H., Marzahn, M. R., McClung, S. H., Yowell, C. A., Stevens, S. M., Dame, J. B. & Dunn, B. M., Oct 28 2015, In : PloS one. 10, 10, e0141758.

Research output: Contribution to journalArticle

plasmepsin
Plasmodium berghei
Vacuoles
malaria
Malaria
69 Citations (Scopus)

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration

Liu, P., Reed, M. N., Kotilinek, L. A., Grant, M. K. O., Forster, C. L., Qiang, W., Shapiro, S. L., Reichl, J. H., Chiang, A. C. A., Jankowsky, J. L., Wilmot, C. M., Cleary, J. P., Zahs, K. R. & Ashe, K. H., Jun 23 2015, In : Cell Reports. 11, 11, p. 1760-1771 12 p.

Research output: Contribution to journalArticle

Oligomers
Amyloid
Alzheimer Disease
Poisons
Amyloid Plaques
2012
6 Citations (Scopus)

Antiplasmodial activities of 4-aminoquinoline-statine compounds

Vaiana, N., Marzahn, M., Parapini, S., Liu, P., Dell'Agli, M., Pancotti, A., Sangiovanni, E., Basilico, N., Bosisio, E., Dunn, B. M., Taramelli, D. & Romeo, S., Sep 15 2012, In : Bioorganic and Medicinal Chemistry Letters. 22, 18, p. 5915-5918 4 p.

Research output: Contribution to journalArticle

Chloroquine
Growth Inhibitors
Cathepsin D
Plasmodium falciparum
Vacuoles
2011
31 Citations (Scopus)

Grape seed polyphenolic extract specifically decreases Aβ*56 in the brains of Tg2576 mice

Liu, P., Kemper, L. J., Wang, J., Zahs, K. R., Ashe, K. H. & Pasinetti, G. M., Jan 1 2011, In : Journal of Alzheimer's Disease. 26, 4, p. 657-666 10 p.

Research output: Contribution to journalArticle

Grape Seed Extract
Alzheimer Disease
Brain
Transgenic Mice
Amyloid beta-Protein Precursor
2010
24 Citations (Scopus)

Effect size of reference memory deficits in the Morris water maze in Tg2576 mice

Reed, M. N., Liu, P., Kotilinek, L. A. & Ashe, K. H., Sep 1 2010, In : Behavioural Brain Research. 212, 1, p. 115-120 6 p.

Research output: Contribution to journalArticle

Memory Disorders
Water
Alzheimer Disease
2009
16 Citations (Scopus)

Recombinant plasmepsin 1 from the human malaria parasite Plasmodium falciparum: Enzymatic characterization, active site inhibitor design, and structural analysis

Liu, P., Marzahn, M. R., Robbins, A. H., Gutiéerrez-de-Terán, H., Rodríguez, D., McClung, S. H., Stevens, S. M., Yowell, C. A., Dame, J. B., McKenna, R. & Dunn, B. M., May 19 2009, In : Biochemistry. 48, 19, p. 4086-4099 14 p.

Research output: Contribution to journalArticle

Peptidomimetics
Falciparum Malaria
Structural analysis
Catalytic Domain
Parasites
2006
26 Citations (Scopus)

High antiplasmodial activity of novel plasmepsins I and II inhibitors

Dell'Agli, M., Parapini, S., Galli, G., Vaiana, N., Taramelli, D., Sparatore, A., Liu, P., Dunn, B. M., Bosisio, E. & Romeo, S., Dec 14 2006, In : Journal of Medicinal Chemistry. 49, 25, p. 7440-7449 10 p.

Research output: Contribution to journalArticle

Chloroquine
Inhibitory Concentration 50
Primaquine
Cathepsin D
Life Cycle Stages
27 Citations (Scopus)

Inhibitor binding to the plasmepsin IV aspartic protease from Plasmodium falciparum

Gutiérrez-De-Terán, H., Nervall, M., Ersmark, K., Liu, P., Janka, L. K., Dunn, B., Hallberg, A. & Åqvist, J., Sep 5 2006, In : Biochemistry. 45, 35, p. 10529-10541 13 p.

Research output: Contribution to journalArticle

Oxadiazoles
Plasmodium falciparum
Parasites
Peptide Hydrolases
Bearings (structural)