Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Fingerprint
The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 1 Active
-
Structure and toxicity of a specific tau oligomer related to dementia
Liu, P. (PI), Ashe, K. H. (CoI) & Liao, D. (CoI)
9/1/24 → 8/31/27
Project: Research project
-
Aβ∗56 is a stable oligomer that impairs memory function in mice
Liu, P., Lapcinski, I. P., Hlynialuk, C. J. W., Steuer, E. L., Loude, T. J., Shapiro, S. L., Kemper, L. J. & Ashe, K. H., Mar 15 2024, In: iScience. 27, 3, 109239.Research output: Contribution to journal › Article › peer-review
Open Access -
Blocking Site-Specific Cleavage of Human Tau Delays Progression of Disease-Related Phenotypes in Genetically Matched Tau-Transgenic Mice Modeling Frontotemporal Dementia
Steuer, E. L., Kemper, L. J., Hlynialuk, C. J. W., Leinonen-Wright, K., Montonye, M. L., Lapcinski, I. P., Forster, C. L., Ashe, K. H. & Liu, P., Jun 8 2022, In: Journal of Neuroscience. 42, 23, p. 4737-4754 18 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Caspase‑2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy
Singh, G., Liu, P., Yao, K. R., Strasser, J. M., Hlynialuk, C., Leinonen-Wright, K., Teravskis, P. J., Choquette, J. M., Ikramuddin, J., Bresinsky, M., Nelson, K. M., Liao, D., Ashe, K. H., Walters, M. A. & Pockes, S., May 18 2022, In: ACS Chemical Neuroscience. 13, 10, p. 1549-1557 9 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314
Bresinsky, M., Strasser, J. M., Vallaster, B., Liu, P., McCue, B., Fuller, J., Hubmann, A., Singh, G., Nelson, K., Cuellar, M. E., Wilmot, C. M., Finzel, B. C., Ashe, K. H., Walters, M. A. & Pockes, S., Jan 14 2022, In: ACS Pharmacology and Translational Science. 5, 1, p. 20-40 21 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
The molecular implications of a caspase-2-mediated site-specific tau cleavage in tauopathies
Liu, P. & Ashe, K. H., Sep 2021, In: Neural Regeneration Research. 16, 9, p. 1774-1775 2 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations