Paul L Bigliardi

Professor

Accepting PhD Students

1993 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Article

Anaphylaxis resulting from selective sensitization to Americana grapes

Bircher, A. J., Bigliardi, P. & Yilmaz, B., Jan 1 1999, In : Journal of Allergy and Clinical Immunology. 104, 5, p. 1111-1113 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Anaphylaxis to the carbohydrate carboxymethylcellulose in parenteral corticosteroid preparations.

Bigliardi, P. L., Izakovic, J., Weber, J. M. & Bircher, A. J., 2003, In : Dermatology (Basel, Switzerland). 207, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

An Asian Perspective on Povidone Iodine in Wound Healing

Bigliardi, P., Langer, S., Cruz, J. J., Kim, S. W., Nair, H. & Srisawasdi, G., Oct 1 2017, In : Dermatology. 233, 2-3, p. 223-233 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

An expedient multiple information processing pattern-generating chromophore

Rout, B., Bigliardi-Qi, M. & Bigliardi, P. L., Jan 1 2017, In : Sensors and Actuators, B: Chemical. 251, p. 164-170 7 p.

Research output: Contribution to journalArticle

Arnica - Une plante magnifique?

Translated title of the contribution: Arnica - a splendid plant?Schwarzkopf, S., Bigliardi, P. L., Panizzon, R. G. & Laffitte, E., Dec 13 2006, In : Revue Medicale Suisse. 2, 91, p. 2884-2885 2 p.

Research output: Contribution to journalArticle

Caspase-3 protects stressed organs against cell death

Khalil, H., Peltzer, N., Walicki, J., Yang, J. Y., Dubuis, G., Gardiol, N., Held, W., Bigliardi, P., Marsland, B., Liaudet, L. & Widmann, C., Nov 1 2012, In : Molecular and cellular biology. 32, 22, p. 4523-4533 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Changes of epidermal mu-opiate receptor expression and nerve endings in chronic atopic dermatitis

Bigliardi-Qi, M., Lipp, B., Sumanovski, L. T., Buechner, S. A. & Bigliardi, P. L., Apr 18 2005, In : Dermatology. 210, 2, p. 91-99 9 p.

Research output: Contribution to journalArticle

66 Scopus citations

Characterization of μ-opiate receptor in human epidermis and keratinocytes

Bigliardi-Qi, M., Bigliardi, P. L., Büchner, S. & Rufli, T., Jan 1 1999, In : Annals of the New York Academy of Sciences. 885, p. 368-371 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Computerized microassay of keratinocyte cell-plastic attachment and proliferation for assessing net stimulatory, inhibitory and toxic effects of compounds on nonimmortalized cell lines

Grando, S. A., Cabrera, R., Hostager, B. S., Bigliardi, P. L., Blake, J. S., Herron, M. J., Dahl, M. V. & Nelson, R. D., Jan 1 1993, In : Skin Pharmacology and Physiology. 6, 2, p. 135-147 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Delayed generalized allergic reactions to corticosteroids

Bircher, A. J., Bigliardi, P., Zaugg, T. & Mäkinen-Kiljunen, S., Jan 1 2000, In : Dermatology. 200, 4, p. 349-351 3 p.

Research output: Contribution to journalArticle

20 Scopus citations

Deletion of δ-opioid receptor in mice alters skin differentiation and delays wound healing

Bigliardi-Qi, M., Gaveriaux-Ruff, C., Zhou, H., Hell, C., Bady, P., Rufli, T., Kieffer, B. & Bigliardi, P. L., Apr 2006, In : Differentiation. 74, 4, p. 174-185 12 p.

Research output: Contribution to journalArticle

43 Scopus citations

Deletion of μ- and κ-opioid receptors in mice changes epidermal hypertrophy, density of peripheral nerve endings, and itch behavior

Bigliardi-Qi, M., Gaveriaux-Ruff, C., Pfaltz, K., Bady, P., Baumann, T., Rufli, T., Kieffer, B. L. & Bigliardi, P. L., Jun 1 2007, In : Journal of Investigative Dermatology. 127, 6, p. 1479-1488 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
46 Scopus citations

Differential Expression between Human Dermal Papilla Cells from Balding and Non-Balding Scalps Reveals New Candidate Genes for Androgenetic Alopecia

Chew, E. G. Y., Tan, J. H. J., Bahta, A. W., Ho, B. S. Y., Liu, X., Lim, T. C., Sia, Y. Y., Bigliardi, P. L., Heilmann, S., Wan, A. C. A., Nöthen, M. M., Philpott, M. P. & Hillmer, A. M., Aug 1 2016, In : Journal of Investigative Dermatology. 136, 8, p. 1559-1567 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Effects of detergents on proliferation and metabolism of human keratinocytes

Bigliardi, P. L., Herron, M. J., Nelson, R. D. & Dahl, M. V., Apr 1994, In : Experimental Dermatology. 3, 2, p. 89-94 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Evaluation of the applicability of the Immuno-solidphase allergen chip (ISAC) assay in atopic patients in Singapore

Santosa, A., Andiappan, A. K., Rotzschke, O., Wong, H. C., Chang, A., Bigliardi-Qi, M., Wang, D. Y. & Bigliardi, P. L., Feb 27 2015, In : Clinical and Translational Allergy. 5, 1, 9.

Research output: Contribution to journalArticle

7 Scopus citations

Expression of μ-opiate receptor in human epidermis and keratinocytes

Bigliardi, P. L., Bigliardi-Qi, M., Buechner, S. & Rufli, T., Jan 1 1998, In : Journal of Investigative Dermatology. 111, 2, p. 297-301 5 p.

Research output: Contribution to journalArticle

84 Scopus citations

Facile synthesis of oligo anilines as permanent hair dyes: How chemical modifications impart colour and avoid toxicity

Venkatesan, G., Dancik, Y., Sinha, A., Bigliardi, M., Srinivas, R., Dawson, T., Valiyaveettil, S., Bigliardi, P. & Pastorin, G., Jan 1 2019, In : New Journal of Chemistry. 43, 41, p. 16188-16199 12 p.

Research output: Contribution to journalArticle

Full-thickness human skin-on-chip with enhanced epidermal morphogenesis and barrier function

Sriram, G., Alberti, M., Dancik, Y., Wu, B., Wu, R., Feng, Z., Ramasamy, S., Bigliardi, P. L., Bigliardi-Qi, M. & Wang, Z., May 2018, In : Materials Today. 21, 4, p. 326-340 15 p.

Research output: Contribution to journalArticle

32 Scopus citations

How best to fight that nasty itch - From new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches

Bíró, T., Ko, M. C., Bromm, B., Wei, E. T., Bigliardi, P., Siebenhaar, F., Hashizume, H., Misery, L., Bergasa, N. V., Kamei, C., Schouenborg, J., Roostermann, D., Szabó, T., Maurer, M., Bigliardi-Qi, M., Meingassner, J. G., Hossen, M. A., Schmelz, M. & Steinhoff, M., Mar 2005, In : Experimental Dermatology. 14, 3, 1 p.

Research output: Contribution to journalArticle

79 Scopus citations

Investigating endogenous µ-opioid receptors in human keratinocytes as pharmacological targets using novel fluorescent ligand

Leong, C., Neumann, C., Ramasamy, S., Rout, B., Wee, L. Y., Bigliardi-Qi, M. & Bigliardi, P. L., Dec 2017, In : PloS one. 12, 12, e0188607.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Keratinocyte muscarinic acetylcholine receptors: Immunolocalization and partial characterization

Grando, S. A., Zelickson, B. D., Kist, D. A., Weinshenker, D., Bigliardi, P. L., Wendelschafer-Crabb, G., Kennedy, W. R. & Dahl, M. V., Jan 1 1995, In : Journal of Investigative Dermatology. 104, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Microbiome in the hair follicle of androgenetic alopecia patients

Ho, B. S. Y., Ho, E. X. P., Chu, C. W., Ramasamy, S., Bigliardi-Qi, M., de Sessions, P. F. & Bigliardi, P. L., Jan 1 2019, In : PloS one. 14, 5, p. e0216330

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Multi-chamber microfluidic platform for high-precision skin permeation testing

Alberti, M., Dancik, Y., Sriram, G., Wu, B., Teo, Y. L., Feng, Z., Bigliardi-Qi, M., Wu, R. G., Wang, Z. P. & Bigliardi, P. L., Jan 1 2017, In : Lab on a chip. 17, 9, p. 1625-1634 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Mu-opiate receptor and beta-endorphin expression in nerve endings and keratinocytes in human skin

Bigliardi-Qi, M., Sumanovski, L. T., Büchner, S., Rufli, T. & Bigliardi, P. L., Oct 27 2004, In : Dermatology. 209, 3, p. 183-189 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Occupational airborne contact dermatitis from diphencyprone in a pharmacy employee

Bircher, A. J., Bigliardi, P., Messmer, S. L. & Surber, C., Jan 1 1999, In : Contact Dermatitis. 41, 1, 1 p.

Research output: Contribution to journalArticle

9 Scopus citations

Opioids and skin homeostasis, regeneration and ageing – What's the evidence?

Bigliardi, P. L., Dancik, Y., Neumann, C. & Bigliardi-Qi, M., Aug 1 2016, In : Experimental Dermatology. 25, 8, p. 586-591 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pattern-Generating Unimolecular Sensors: For Future Differential Sensing and Molecular Computing

Rout, B. & Bigliardi, P. L., Jun 1 2017, In : Synlett. 28, 9, p. 1005-1010 6 p., st-2016-p0798-sp.

Research output: Contribution to journalArticle

4 Scopus citations

Physical and compositional analysis of differently cultured 3D human skin equivalents by confocal Raman spectroscopy

Dancik, Y., Sriram, G., Rout, B., Zou, Y., Bigliardi-Qi, M. & Bigliardi, P. L., Mar 7 2018, In : Analyst. 143, 5, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Physiological Doses of Red Light Induce IL-4 Release in Cocultures between Human Keratinocytes and Immune Cells

Leong, C., Bigliardi, P. L., Sriram, G., Au, V. B., Connolly, J. & Bigliardi-Qi, M., Jan 1 2018, In : Photochemistry and Photobiology. 94, 1, p. 150-157 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia

Ho, B. S. Y., Vaz, C., Ramasamy, S., Chew, E. G. Y., Mohamed, J. S., Jaffar, H., Hillmer, A., Tanavde, V., Bigliardi-Qi, M. & Bigliardi, P. L., Dec 1 2019, In : Scientific reports. 9, 1, 8771.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Reconstructing human skin equivalents on fibrin-based dermal matrix: Reproducible human skin equivalents with superior epidermal reconstruction

Sriram, G., Dykas, M. M., Ramasamy, S., Poddar, K., Krishnan-Kutty, V., Patra, A., Venkatesan, T., Bigliardi-Qi, M. & Bigliardi, P. L., Apr 1 2016, In : Materials Today. 19, 3, p. 178-179 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Role of Skin pH in Psoriasis

Bigliardi, P. L., Jan 1 2018, In : Current Problems in Dermatology (Switzerland). 54, p. 108-114 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Selective Susceptibility of Human Skin Antigen Presenting Cells to Productive Dengue Virus Infection

Cerny, D., Haniffa, M., Shin, A., Bigliardi, P., Tan, B. K., Lee, B., Poidinger, M., Tan, E. Y., Ginhoux, F. & Fink, K., Dec 1 2014, In : PLoS pathogens. 10, 12

Research output: Contribution to journalArticle

53 Scopus citations

Specific stimulation of migration of human keratinocytes by μ-opiate receptor agonists

Bigliardi, P. L., Büchner, S., Rufli, T. & Bigliardi-Qi, M., Dec 1 2002, In : Journal of Receptors and Signal Transduction. 22, 1-4, p. 191-199 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Specific Targeting of Melanotic Cells with Peptide Ligated Photosensitizers for Photodynamic Therapy

Bigliardi, P. L., Rout, B., Pant, A., Krishnan-Kutty, V., Eberle, A. N., Srinivas, R., Burkett, B. A. & Bigliardi-Qi, M., Dec 1 2017, In : Scientific reports. 7, 1, 15750.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Structural and Functional Analysis of Intact Hair Follicles and Pilosebaceous Units by Volumetric Multispectral Optoacoustic Tomography

Ford, S. J., Bigliardi, P. L., Sardella, T. C. P., Urich, A., Burton, N. C., Kacprowicz, M., Bigliardi, M., Olivo, M. & Razansky, D., Jan 1 2016, In : Journal of Investigative Dermatology. 136, 4, p. 753-761 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers

Grouzmann, E., Bigliardi, P., Appenzeller, M., Pannatier, A. & Buclin, T., Mar 1 2011, In : Biological Chemistry. 392, 3, p. 217-221 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
4 Scopus citations

The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3

Neumann, C., Bigliardi-Qi, M., Widmann, C. & Bigliardi, P. L., Feb 13 2015, In : Journal of Investigative Dermatology. 135, 2, p. 471-480 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Treatment of pruritus with topically applied opiate receptor antagonist

Bigliardi, P. L., Stammer, H., Jost, G., Rufli, T., Büchner, S. & Bigliardi-Qi, M., Jun 1 2007, In : Journal of the American Academy of Dermatology. 56, 6, p. 979-988 10 p.

Research output: Contribution to journalArticle

82 Scopus citations

Unilateral aplasia cutis congenita on the leg

Bigliardi, P. L., Braschler, C., Kuhn, P., Sigrist, J., Buechner, S. & Rufli, T., Jul 1 2004, In : Pediatric Dermatology. 21, 4, p. 454-457 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Ursachen, diagnose und therapie von pruritus

Translated title of the contribution: Causes, diagnosis and treatment of pruritusBigliardi, P. L., Nov 1 2006, In : Aktuelle Dermatologie. 32, 11, p. 468-473 6 p.

Research output: Contribution to journalArticle

Wheat-dependent exercise-induced anaphylaxis: A retrospective case review from a tertiary hospital

Thalayasingam, M., Allameen, N. A., Soh, J. Y., Bigliardi, P., Van Bever, H. & Shek, L. P. C., Sep 2014, In : Postgraduate Medical Journal. 90, 1067, p. 488-492 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

β-Endorphin stimulates cytokeratin 16 expression and downregulates μ- opiate receptor expression in human epidermis

Bigliardi-Qi, M., Bigliardi, P. L., Eberle, A. N., Büchner, S. & Rufli, T., Jan 1 2000, In : Journal of Investigative Dermatology. 114, 3, p. 527-532 6 p.

Research output: Contribution to journalArticle

53 Scopus citations
Chapter

Full-thickness human skin equivalent models of atopic dermatitis

Sriram, G., Bigliardi, P. L. & Bigliardi-Qi, M., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 367-383 17 p. (Methods in Molecular Biology; vol. 1879).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

The roles of opioid receptors in cutaneous wound healing

Bigliardi-Qi, M. & Bigliardi, P., Jan 1 2018, Handbook of Experimental Pharmacology. Springer New York LLC, p. 335-345 11 p. (Handbook of Experimental Pharmacology; vol. 247).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
Comment/debate

Chronic idiopathic urticaria successfully treated by anticoagulant drug

Spring, P., Angelillo-Scherrer, A. & Bigliardi, P., Dec 1 2012, In : European Journal of Dermatology. 22, 6, p. 788-790 3 p.

Research output: Contribution to journalComment/debate

4 Scopus citations

Stevens-Johnson syndrome/toxic epidermal necrolysis overlap induced by fexofenadine

Teo, S. L., Santosa, A. & Bigliardi, P. L., Jan 1 2017, In : Journal of Investigational Allergology and Clinical Immunology. 27, 3, p. 191-193 3 p.

Research output: Contribution to journalComment/debate

3 Scopus citations
Conference contribution

High-throughput microfluidic chip for automated in vitro release testing

Alberti, M., Dancik, Y., Wu, B., Feng, Z., Wu, R. G., Bigliardi-Qi, M., Bigliardi, P. L. & Wang, Z. P., Jan 1 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 589-590 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution