Paul L Bigliardi

Professor

Accepting PhD Students

1993 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

β-Endorphin stimulates cytokeratin 16 expression and downregulates μ- opiate receptor expression in human epidermis

Bigliardi-Qi, M., Bigliardi, P. L., Eberle, A. N., Büchner, S. & Rufli, T., Jan 1 2000, In : Journal of Investigative Dermatology. 114, 3, p. 527-532 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Wheat-dependent exercise-induced anaphylaxis: A retrospective case review from a tertiary hospital

Thalayasingam, M., Allameen, N. A., Soh, J. Y., Bigliardi, P., Van Bever, H. & Shek, L. P. C., Sep 2014, In : Postgraduate Medical Journal. 90, 1067, p. 488-492 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
6 Scopus citations

UV-B induces cytoplasmic survivin expression in mouse epidermis

Peltzer, N., Bigliardi, P. & Widmann, C., Sep 1 2012, In : Journal of Dermatological Science. 67, 3, p. 196-199 4 p.

Research output: Contribution to journalLetter

3 Scopus citations

Ursachen, diagnose und therapie von pruritus

Translated title of the contribution: Causes, diagnosis and treatment of pruritusBigliardi, P. L., Nov 1 2006, In : Aktuelle Dermatologie. 32, 11, p. 468-473 6 p.

Research output: Contribution to journalArticle

Unilateral aplasia cutis congenita on the leg

Bigliardi, P. L., Braschler, C., Kuhn, P., Sigrist, J., Buechner, S. & Rufli, T., Jul 1 2004, In : Pediatric Dermatology. 21, 4, p. 454-457 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Treatment of pruritus with topically applied opiate receptor antagonist

Bigliardi, P. L., Stammer, H., Jost, G., Rufli, T., Büchner, S. & Bigliardi-Qi, M., Jun 1 2007, In : Journal of the American Academy of Dermatology. 56, 6, p. 979-988 10 p.

Research output: Contribution to journalArticle

83 Scopus citations

The δ-opioid receptor affects epidermal homeostasis via ERK-dependent inhibition of transcription factor POU2F3

Neumann, C., Bigliardi-Qi, M., Widmann, C. & Bigliardi, P. L., Feb 13 2015, In : Journal of Investigative Dermatology. 135, 2, p. 471-480 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

The roles of opioid receptors in cutaneous wound healing

Bigliardi-Qi, M. & Bigliardi, P., Jan 1 2018, Handbook of Experimental Pharmacology. Springer New York LLC, p. 335-345 11 p. (Handbook of Experimental Pharmacology; vol. 247).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
4 Scopus citations

Synthetic peptide drugs for targeting skin cancer: Malignant melanoma and melanotic lesions

Eberle, A. N., Rout, B., Bigliardi-Qi, M. & Bigliardi, P. L., Jan 1 2017, In : Current medicinal chemistry. 24, 17, p. 1797-1826 30 p.

Research output: Contribution to journalReview article

4 Scopus citations

Superior differentiation in full thickness human skin-on-a-chip

Alberti, M., Sriram, G., Dancik, Y., Wu, B., Wu, R., Ramasamy, S., Bigliardi-Qi, M., Bigliardi, P. L. & Wang, Z., Jan 1 2020, 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017. Chemical and Biological Microsystems Society, p. 1121-1122 2 p. (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Substance P-induced skin inflammation is not modulated by a single dose of sitagliptin in human volunteers

Grouzmann, E., Bigliardi, P., Appenzeller, M., Pannatier, A. & Buclin, T., Mar 1 2011, In : Biological Chemistry. 392, 3, p. 217-221 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Structural and Functional Analysis of Intact Hair Follicles and Pilosebaceous Units by Volumetric Multispectral Optoacoustic Tomography

Ford, S. J., Bigliardi, P. L., Sardella, T. C. P., Urich, A., Burton, N. C., Kacprowicz, M., Bigliardi, M., Olivo, M. & Razansky, D., Jan 1 2016, In : Journal of Investigative Dermatology. 136, 4, p. 753-761 9 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Stevens-Johnson syndrome/toxic epidermal necrolysis overlap induced by fexofenadine

Teo, S. L., Santosa, A. & Bigliardi, P. L., Jan 1 2017, In : Journal of Investigational Allergology and Clinical Immunology. 27, 3, p. 191-193 3 p.

Research output: Contribution to journalComment/debate

Open Access
3 Scopus citations

Specific Targeting of Melanotic Cells with Peptide Ligated Photosensitizers for Photodynamic Therapy

Bigliardi, P. L., Rout, B., Pant, A., Krishnan-Kutty, V., Eberle, A. N., Srinivas, R., Burkett, B. A. & Bigliardi-Qi, M., Dec 1 2017, In : Scientific reports. 7, 1, 15750.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Specific stimulation of migration of human keratinocytes by μ-opiate receptor agonists

Bigliardi, P. L., Büchner, S., Rufli, T. & Bigliardi-Qi, M., Dec 1 2002, In : Journal of Receptors and Signal Transduction. 22, 1-4, p. 191-199 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Selective Susceptibility of Human Skin Antigen Presenting Cells to Productive Dengue Virus Infection

Cerny, D., Haniffa, M., Shin, A., Bigliardi, P., Tan, B. K., Lee, B., Poidinger, M., Tan, E. Y., Ginhoux, F. & Fink, K., Dec 1 2014, In : PLoS pathogens. 10, 12

Research output: Contribution to journalArticle

55 Scopus citations

Role of Skin pH in Psoriasis

Bigliardi, P. L., Jan 1 2018, In : Current Problems in Dermatology (Switzerland). 54, p. 108-114 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Reconstructing human skin equivalents on fibrin-based dermal matrix: Reproducible human skin equivalents with superior epidermal reconstruction

Sriram, G., Dykas, M. M., Ramasamy, S., Poddar, K., Krishnan-Kutty, V., Patra, A., Venkatesan, T., Bigliardi-Qi, M. & Bigliardi, P. L., Apr 1 2016, In : Materials Today. 19, 3, p. 178-179 2 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Pyoderma gangrenosum mimicking early acute infection following total knee arthroplasty

Yik, J. H., Bigliardi, P. L., Sebastin, S. J., Cabucana, N. J., Venkatachalam, I. & Krishna, L., Jan 1 2015, In : Annals of the Academy of Medicine Singapore. 44, 4, p. 150-151 2 p.

Research output: Contribution to journalLetter

2 Scopus citations

Prurit: Causes, diagnostic et traitement

Translated title of the contribution: Pruritus - Causes, diagnostics and treatmentBigliardi, P. L., Apr 26 2006, In : Revue Medicale Suisse. 2, 63, p. 1115-1121 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia

Ho, B. S. Y., Vaz, C., Ramasamy, S., Chew, E. G. Y., Mohamed, J. S., Jaffar, H., Hillmer, A., Tanavde, V., Bigliardi-Qi, M. & Bigliardi, P. L., Dec 1 2019, In : Scientific reports. 9, 1, 8771.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Povidone iodine in wound healing: A review of current concepts and practices

Bigliardi, P. L., Alsagoff, S. A. L., El-Kafrawi, H. Y., Pyon, J. K., Wa, C. T. C. & Villa, M. A., Aug 2017, In : International Journal of Surgery. 44, p. 260-268 9 p.

Research output: Contribution to journalReview article

Open Access
42 Scopus citations

Physiological Doses of Red Light Induce IL-4 Release in Cocultures between Human Keratinocytes and Immune Cells

Leong, C., Bigliardi, P. L., Sriram, G., Au, V. B., Connolly, J. & Bigliardi-Qi, M., Jan 1 2018, In : Photochemistry and Photobiology. 94, 1, p. 150-157 8 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Physical and compositional analysis of differently cultured 3D human skin equivalents by confocal Raman spectroscopy

Dancik, Y., Sriram, G., Rout, B., Zou, Y., Bigliardi-Qi, M. & Bigliardi, P. L., Mar 7 2018, In : Analyst. 143, 5, p. 1065-1076 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Peripheral nerve fibres form multifacet interactions with keratinocytes in a novel complete human 2D culture model

Krishnan-Kutty, V., Bigliardi, P. L., Dykas, M. M., Pomp, O., Kyaw, H. M., Poddar, K., Venkatesan, T. & Bigliardi-Qi, M., Mar 1 2017, In : Experimental Dermatology. 26, 3, p. 281-284 4 p.

Research output: Contribution to journalLetter

Open Access
4 Scopus citations

Pattern-Generating Unimolecular Sensors: For Future Differential Sensing and Molecular Computing

Rout, B. & Bigliardi, P. L., Jun 1 2017, In : Synlett. 28, 9, p. 1005-1010 6 p., st-2016-p0798-sp.

Research output: Contribution to journalArticle

4 Scopus citations

Pansements bioactifs

Translated title of the contribution: Bioactive dressingsGrasset, N., Raffoul, W. & Bigliardi, P., Feb 17 2010, In : Revue Medicale Suisse. 6, 236, p. 354-357 4 p.

Research output: Contribution to journalShort survey

3 Scopus citations

Oral tolerance of carboxymethylcellulose in patients with anaphylaxis to parenteral carboxymethylcellulose [2]

Bircher, A. J., Izakovic, J. & Bigliardi, P. L., May 2004, In : Annals of Allergy, Asthma and Immunology. 92, 5, p. 580-581 2 p.

Research output: Contribution to journalLetter

10 Scopus citations

Opioids and the skin - Where do we stand?

Bigliardi, P. L., Tobin, D. J., Gaveriaux-Ruff, C. & Bigliardi-Qi, M., Apr 29 2009, In : Experimental Dermatology. 18, 5, p. 424-430 7 p.

Research output: Contribution to journalReview article

82 Scopus citations

Opioids and skin homeostasis, regeneration and ageing – What's the evidence?

Bigliardi, P. L., Dancik, Y., Neumann, C. & Bigliardi-Qi, M., Aug 1 2016, In : Experimental Dermatology. 25, 8, p. 586-591 6 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Occupational airborne contact dermatitis from diphencyprone in a pharmacy employee

Bircher, A. J., Bigliardi, P., Messmer, S. L. & Surber, C., Jan 1 1999, In : Contact Dermatitis. 41, 1, 1 p.

Research output: Contribution to journalArticle

9 Scopus citations

Mu-opiate receptor and beta-endorphin expression in nerve endings and keratinocytes in human skin

Bigliardi-Qi, M., Sumanovski, L. T., Büchner, S., Rufli, T. & Bigliardi, P. L., Oct 27 2004, In : Dermatology. 209, 3, p. 183-189 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Multi-chamber microfluidic platform for high-precision skin permeation testing

Alberti, M., Dancik, Y., Sriram, G., Wu, B., Teo, Y. L., Feng, Z., Bigliardi-Qi, M., Wu, R. G., Wang, Z. P. & Bigliardi, P. L., May 7 2017, In : Lab on a chip. 17, 9, p. 1625-1634 10 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Microbiome in the hair follicle of androgenetic alopecia patients

Ho, B. S. Y., Ho, E. X. P., Chu, C. W., Ramasamy, S., Bigliardi-Qi, M., de Sessions, P. F. & Bigliardi, P. L., May 3 2019, In : PloS one. 14, 5, e0216330.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Kortikosteroide zur lokalen Anwendung auf der Haut

Translated title of the contribution: Corticosteroids for topical skin applicationKahmann, I. V., Gabard, B. & Bigliardi, P. L., Dec 5 2008, In : Pharma-Kritik. 30, 8-9, p. 29-36 8 p.

Research output: Contribution to journalReview article

Keratinocyte muscarinic acetylcholine receptors: Immunolocalization and partial characterization

Grando, S. A., Zelickson, B. D., Kist, D. A., Weinshenker, D., Bigliardi, P. L., Wendelschafer-Crabb, G., Kennedy, W. R. & Dahl, M. V., Jan 1 1995, In : Journal of Investigative Dermatology. 104, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

70 Scopus citations

Investigating endogenous µ-opioid receptors in human keratinocytes as pharmacological targets using novel fluorescent ligand

Leong, C., Neumann, C., Ramasamy, S., Rout, B., Wee, L. Y., Bigliardi-Qi, M. & Bigliardi, P. L., Dec 2017, In : PloS one. 12, 12, e0188607.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

How best to fight that nasty itch - From new insights into the neuroimmunological, neuroendocrine, and neurophysiological bases of pruritus to novel therapeutic approaches

Bíró, T., Ko, M. C., Bromm, B., Wei, E. T., Bigliardi, P., Siebenhaar, F., Hashizume, H., Misery, L., Bergasa, N. V., Kamei, C., Schouenborg, J., Roostermann, D., Szabó, T., Maurer, M., Bigliardi-Qi, M., Meingassner, J. G., Hossen, M. A., Schmelz, M. & Steinhoff, M., Mar 2005, In : Experimental Dermatology. 14, 3, 1 p.

Research output: Contribution to journalArticle

78 Scopus citations

High-throughput microfluidic chip for automated in vitro release testing

Alberti, M., Dancik, Y., Wu, B., Feng, Z., Wu, R. G., Bigliardi-Qi, M., Bigliardi, P. L. & Wang, Z. P., Jan 1 2016, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 589-590 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Full-thickness human skin-on-chip with enhanced epidermal morphogenesis and barrier function

Sriram, G., Alberti, M., Dancik, Y., Wu, B., Wu, R., Feng, Z., Ramasamy, S., Bigliardi, P. L., Bigliardi-Qi, M. & Wang, Z., May 2018, In : Materials Today. 21, 4, p. 326-340 15 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Full-thickness human skin equivalent models of atopic dermatitis

Sriram, G., Bigliardi, P. L. & Bigliardi-Qi, M., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 367-383 17 p. (Methods in Molecular Biology; vol. 1879).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Fibroblast heterogeneity and its implications for engineering organotypic skin models in vitro

Sriram, G., Bigliardi, P. L. & Bigliardi-Qi, M., Jan 1 2015, In : European Journal of Cell Biology. 94, 11, p. 483-512 30 p.

Research output: Contribution to journalReview article

90 Scopus citations

Facile synthesis of oligo anilines as permanent hair dyes: How chemical modifications impart colour and avoid toxicity

Venkatesan, G., Dancik, Y., Sinha, A., Bigliardi, M., Srinivas, R., Dawson, T., Valiyaveettil, S., Bigliardi, P. & Pastorin, G., Jan 1 2019, In : New Journal of Chemistry. 43, 41, p. 16188-16199 12 p.

Research output: Contribution to journalArticle

Expression of μ-opiate receptor in human epidermis and keratinocytes

Bigliardi, P. L., Bigliardi-Qi, M., Buechner, S. & Rufli, T., Jan 1 1998, In : Journal of Investigative Dermatology. 111, 2, p. 297-301 5 p.

Research output: Contribution to journalArticle

85 Scopus citations

Expression of peropsin in human skin is related to phototransduction of violet light in keratinocytes

Toh, P. P. C., Bigliardi-Qi, M., Yap, A. M. Y., Sriram, G. & Bigliardi, P., Dec 1 2016, In : Experimental Dermatology. 25, 12, p. 1002-1005 4 p.

Research output: Contribution to journalLetter

14 Scopus citations

Evaluation of the applicability of the Immuno-solidphase allergen chip (ISAC) assay in atopic patients in Singapore

Santosa, A., Andiappan, A. K., Rotzschke, O., Wong, H. C., Chang, A., Bigliardi-Qi, M., Wang, D. Y. & Bigliardi, P. L., Feb 27 2015, In : Clinical and Translational Allergy. 5, 1, 9.

Research output: Contribution to journalArticle

8 Scopus citations

Epidermolyse nécrosante suraiguë de Lyell ou toxic epidermal necrolysis

Translated title of the contribution: Toxic epidermal necrolysisBigliardi, P. L., Raffoul, W. & Berger, M. M., May 2 2007, In : Revue Medicale Suisse. 3, 109, p. 1112-1118 7 p.

Research output: Contribution to journalReview article

Effects of detergents on proliferation and metabolism of human keratinocytes

Bigliardi, P. L., Herron, M. J., Nelson, R. D. & Dahl, M. V., Apr 1994, In : Experimental Dermatology. 3, 2, p. 89-94 6 p.

Research output: Contribution to journalArticle

25 Scopus citations