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Personal profile
Personal profile
Paul A. Iaizzo, PhD FHRS, is a Professor in the Departments of Surgery, Integrative Biology & Physiology and the Carlson School of Management, at the University of Minnesota. He also serves on the graduate faculties in Biomedical Engineering, Neuroscience, Integrative Biology & Physiology, Biological Science, Bioinformatics and Computational Biology and Mechanical Engineering. He is the Director of the Malignant Hyperthermia Diagnostic Center and Medtronic Professor of Visible Heart®️ Research. Additionally, he is the Associate Director and Medtronic Chair of the Institute for Engineering in Medicine, also at the University of Minnesota. He earned both MS and PhD degrees (Focus: Physiology/Neurophysiology) from the University of Minnesota.
In 2002, he was acknowledged as a “Distinguished University Teaching Professor”. Since 1990, he has trained over 200 graduate students, postdoctoral fellows, and medical students in his laboratories. Dr. Iaizzo, has authored more than 290 original articles, over 100 book chapters, edited 5 books, and is on numerous patents related to medical devices. In 2012, he was named to College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE) for "outstanding contributions to research and education in translational systems physiology and cardiovascular engineering". In 2015 he was named a Fellow of the Heart Rhythm Society and in 2016 was made a Senior Fellow of IEEE. In 2023, he was inducted into the “Academy for Excellence in the Scholarship of Teaching and Learning” within the U’s Medical School.
Research interests
To learn more about Dr. Iaizzo’s research, please visit the Visible Heart Laboratories website.
His main research focus is translational systems physiology, where his research group does a broad range of studies. The Visible Heart®️ Laboratories are well known for their multimodal imaging techniques of functional cardiac anatomies and device testing within large mammalian hearts, including human: see the Atlas of Human Cardiac Anatomy (http://www.vhlab.umn.edu/atlas/). Other research areas include: cardiac pacing and ablation, muscle pathophysiology and biophysical properties, thermoregulation, black bear hibernation, 3D computational modeling and printing and educational uses of virtual reality.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Organ banking for transplant-kidney cryopreservation by vitrification and novel nanowarming technology
Finger, E. B. (PI), Adams, A. B. (CoI), Bischof, J. C. (CoI) & Iaizzo, P. A. (CoI)
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
4/14/23 → 3/31/27
Project: Research project
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CT scans of a pig heart with and without a transcatheter
Iaizzo, P. A. (PI)
3/1/97 → 4/30/30
Project: Research project
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ATP-Bio: NSF Engineering Research Center for Advanced Technologies for the Preservation of Biological Systems (ATP-Bio)
Bischof, J. C. (PI), Toner, M. (CoPI), Aguilar, G. (CoPI), Healy, K. E. (CoPI), Uygun, K. (Key Personnel), Burger, A. A. (Project Manager), Wolf, S. M. (Key Personnel), Roehrig, G. H. (Key Personnel), Heremans, C. (Coordinator), McAlpine, M. (Key Personnel), Mangolini, L. (Key Personnel), Uygun, B. E. (Key Personnel), Finger, E. B. (Key Personnel), Garwood, M. (Key Personnel), Dames, C. (Key Personnel), Powell-Palm, M. J. (Key Personnel), Franklin, R. R. (Key Personnel), Singh, B. N. (Key Personnel), Yin, Y. (Key Personnel), Usta, O. B. (Key Personnel), Rubinsky, B. (Key Personnel), Tessier, S. N. (Key Personnel), Sandlin, R. D. (Key Personnel), Kangas, J. R. (Key Personnel), Iaizzo, P. A. (Key Personnel), Irimia, D. (Key Personnel), Ogle, B. M. (Key Personnel), Stadler, B. J. (Key Personnel), Bangalore Kodandaramaiah, S. (Key Personnel), Aksan, A. (Key Personnel) & Rabin, Y. (Key Personnel)
9/1/20 → 8/31/25
Project: Research and Outreach Center
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Neural tissue cryo-susceptibility
Bischof, J. C. (PI) & Iaizzo, P. A. (CoI)
MEDICAL IMMERSION TECHNOLOGY (MIT) SARL
4/1/19 → 12/14/21
Project: Research project
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How Have Black Bears Responded to Diminished Natural Foo
Iaizzo, P. A. (PI)
MINNESOTA DEPARTMENT OF NATURAL RESOURCE
7/5/18 → 8/31/18
Project: Research project
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Anatomic, electrical, and hemodynamic characterization of Bachmann bundle in the swine heart
Duong, N. C., Yang, Z. & Iaizzo, P. A., Nov 1 2025, In: Heart Rhythm. 22, 11, p. 2737-2743 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Coronary Perfusion Following a Transcatheter Aortic Valve Replacement in Either Reanimated Swine or Preserved Human Hearts
Bielecki, M. A., Spencer, J. H. & Iaizzo, P. A., Sep 2025, In: Reviews in Cardiovascular Medicine. 26, 9, 40103.Research output: Contribution to journal › Article › peer-review
Open Access -
Corrigendum to ‘High-Definition Intravascular Ultrasound Versus Optical Coherence Tomography: Lumen Size and Plaque Morphology’ [Journal of the Society for Cardiovascular Angiography & Interventions; 4 (2025) 102520]
Wu, W., Zhao, S., Banga, A., Trivedi, Y. V., Dasari, V. S., Munjal, P., Bhat, R. R., Tapia-Orihuela, R. K. A., Oguz, U. M., Zafar, H., Darapaneni, H., Spilias, N., Wagner, J., Morin, S., DeVos, A., Iaizzo, P. A., Maehara, A., Shlofmitz, E. S., Ali, Z. A. & Brilakis, E. & 3 others, , 2025, (Accepted/In press) In: Journal of the Society for Cardiovascular Angiography and Interventions. 103945.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Development of an Educational Application of Multimodal Imaging of Clinically Implanted and Bifurcation Stenting Procedures
DeVos, A. N., Buyck, D. & Iaizzo, P. A., Mar 2025, In: Journal of the Society for Cardiovascular Angiography and Interventions. 4, 3, 102499.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
DIGITAL HISTOLOGY OF INTACT ORGANS: IODINE PERFUSION OF FIXED HUMAN HEARTS ALLOWS FOR CONTRAST ENHANCED MICRO COMPUTED TOMOGRAPHY
Duong, N., Wethington, A. & Iaizzo, P. A., 2025, Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025. American Society of Mechanical Engineers (ASME), V001T06A007. (Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open Access
Datasets
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Supporting data for "3D printed patient-specific aortic root models with internal sensors for minimally invasive applications"
Haghiashtiani, G., Qiu, K., Zhingre Sanchez, J. D., Fuenning, Z. J., Nair, P., Ahlberg, S. E., Iaizzo, P. A. & McAlpine, M., Data Repository for the University of Minnesota, 2020
DOI: 10.13020/xjv7-s394, http://hdl.handle.net/11299/213919
Dataset
Press/Media
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How surgeons learned to operate on beating hearts
7/9/20
1 item of Media coverage
Press/Media: Expert Comment or Interview