Pamala A Jacobson

Professor, College of Pharmacy, Experimental and Clinical Pharmacology

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26 Similar Profiles

Mycophenolic Acid Medicine & Life Sciences

Tacrolimus Medicine & Life Sciences

Transplants Medicine & Life Sciences

Cell Transplantation Medicine & Life Sciences

Kidney Medicine & Life Sciences

Cytochrome P-450 CYP3A Medicine & Life Sciences

Pharmacokinetics Medicine & Life Sciences

Graft vs Host Disease Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Cancer Center Support Grant

Yee, D., Bagchi, A., Bielinsky, A. K., Bitterman, P. B., Cooley, S. A., Gupta, K., Hatsukami, D. K., Hecht, S. S., Hirsch, B. A., Jacobson, P. A., Joseph, A. M., Kirstein, M. N., Konety, B. R., Kratzke, R. A., Kuntz, K. M., Lange, C. A., Largaespada, D. A., Lazovich, D., Le, C. T., Mc Carthy, J. B., Miller, J. S., O'Sullivan, G., Okuyemi, K., Pennell, C. A., Shimizu, Y., Sumpmann, M., Verneris, M. R., Vickers, S., Wagner, J. E., Weigel, B. J. & Weisdorf, D. J.

NIH NATIONAL CANCER INSTITUTE (NCI)

3/5/14 → 1/31/19

Project: Research project

Neoplasms

Supplement-Genomics of Kidney Transplantation

Matas, A. J. & Jacobson, P. A.

NIH Nat'l Inst of Allergy & Infect Dis

8/31/16 → 7/31/18

Project: Research project

Genomics

Kidney Transplantation

Identification and Development of Genetic Polymorphisms

Arora, M., Basu, S., Jacobson, P. A., Kuang, R. & Oetting, W. S.

NIH Nat'l Inst of Allergy & Infect Dis

7/1/08 → 6/30/11

Project: Research project

Graft vs Host Disease

Genetic Polymorphisms

Biomarkers

Study of Mycophenolic Acid Exposure in Subjects with Acu

Jacobson, P. A.

ROCHE LAB INC

11/1/04 → 12/31/07

Project: Research project

Mycophenolic Acid

Cell Transplantation

Research Output 1992 2018

71 Article
5 Review article
3 Letter
2 Comment/debate
4 More

1 Citations

Attempted validation of 44 reported SNPs associated with tacrolimus troughs in a cohort of kidney allograft recipients

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Remmel, R. P., Dorr, C., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., Feb 1 2018, In : Pharmacogenomics. 19, 3, p. 175-184 10 p.

Research output: Contribution to journal › Article

Tacrolimus

Cytochrome P-450 CYP3A

Single Nucleotide Polymorphism

Allografts

Kidney

2 Citations

Genetics of acute rejection after kidney transplantation

Dorr, C. R., Oetting, W. S., Jacobson, P. A. & Israni, A. K., Mar 1 2018, In : Transplant International. 31, 3, p. 263-277 15 p.

Research output: Contribution to journal › Review article

Kidney Transplantation

Pharmacogenetics

Genotype

Phenotype

Kidney

1 Citations

Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients

Oetting, W. S., Wu, B., Schladt, D. P., Guan, W., Remmel, R. P., Mannon, R. B., Matas, A. J., Israni, A. K. & Jacobson, P. A., May 22 2018, In : Pharmacogenomics Journal. 18, 3, p. 501-505 5 p.

Research output: Contribution to journal › Article

Cytochrome P-450 CYP3A

Genome-Wide Association Study

Tacrolimus

Kidney

Gene Frequency

Mycophenolic Acid and Its Metabolites in Kidney Transplant Recipients: A Semimechanistic Enterohepatic Circulation Model to Improve Estimating Exposure

Okour, M., Jacobson, P. A., Ahmed, M. A., Israni, A. K. & Brundage, R. C., May 1 2018, In : Journal of Clinical Pharmacology. 58, 5, p. 628-639 12 p.

Research output: Contribution to journal › Article

Enterohepatic Circulation

Mycophenolic Acid

Kidney

Single Nucleotide Polymorphism

Hepatocyte Nuclear Factor 1

1 Citations

NPHP1 (Nephrocystin-1) gene deletions cause adult-onset ESRD

Snoek, R. , Van Setten, J. , Keating, B. J. , Israni, A. K. , Jacobson, P. A. , Oetting, W. S. , Matas, A. J. , Mannon, R. B. , Zhang, Z. , Zhang, W. , Hao, K. , Murphy, B. , Reindl-Schwaighofer, R. , Heinzl, A. , Oberbauer, R. , Viklicky, O. , Conlon, P. J. , Stapleton, C. P. , Bakker, S. J. L. , Snieder, H. & 5 others Peters, E. D. J., Van Der Zwaag, B., Knoers, N. V. A. M., De Borst, M. H. & Van Eerde, A. M., Jun 1 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1772-1779 8 p.

Research output: Contribution to journal › Article

Gene Deletion

Chronic Kidney Failure

Genetic Research

Mutation

Translational Medical Research