20102014

Research output per year

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Personal profile

Research interests

  • Synthetic organic chemistry
  • Chemistry of natural products (terpenes and fatty acids). The development of new routes of natural products
  • Production from natural sources for the purpose of using them as starting materials for organic syntheses
  • Process development of natural products production
  • Chemical modification of natural products for biological tests
  • Synthesis of drugs and drug intermediates base on a triterpenes

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 11 Similar Profiles

Research Output

New derivatives of lupane triterpenoids disturb breast cancer mitochondria and induce cell death

Serafim, T. L., Carvalho, F. S., Bernardo, T. C., Pereira, G. C., Perkins, E., Holy, J., Krasutsky, D. A., Kolomitsyna, O. N., Krasutsky, P. A. & Oliveira, P. J., Nov 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 21, p. 6270-6287 18 p.

Research output: Contribution to journalArticle

  • 16 Scopus citations

    Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition

    Bernardo, T. C., Cunha-Oliveira, T., Serafim, T. L., Holy, J., Krasutsky, D., Kolomitsyna, O., Krasutsky, P., Moreno, A. M. & Oliveira, P. J., Dec 1 2013, In : Bioorganic and Medicinal Chemistry. 21, 23, p. 7239-7249 11 p.

    Research output: Contribution to journalArticle

  • 20 Scopus citations

    Triterpene derivatives that inhibit human immunodeficiency virus type 1 replication

    Dorr, C. R., Yemets, S. V., Kolomitsyna, O. N., Krasutsky, P. & Mansky, L. M., Jan 1 2011, In : Bioorganic and Medicinal Chemistry Letters. 21, 1, p. 542-545 4 p.

    Research output: Contribution to journalArticle

  • 19 Scopus citations

    Dimethylaminopyridine derivatives of lupane triterpenoids are potent disruptors of mitochondrial structure and function

    Holy, J. M., Kolomitsyna, O. N., Krasutsky, D., Oliveira, P. J., Perkins, E. & Krasutsky, P. A., Aug 15 2010, In : Bioorganic and Medicinal Chemistry. 18, 16, p. 6080-6088 9 p.

    Research output: Contribution to journalArticle

  • 19 Scopus citations