Biochemistry, Genetics and Molecular Biology
Phosphotransferase
100%
Kinase
100%
Protein Kinases
36%
Aurora A Kinase
32%
Receptor Tyrosine Kinase
25%
Cyclin-Dependent Kinase 2
24%
Tyrosine Kinase
24%
Allosteric Regulation
20%
Adenosine Triphosphate
20%
Cooperation
18%
C-Terminus
17%
Aurora Kinase
16%
Proliferating Cell Nuclear Antigen
16%
Cyclin
16%
Bosutinib
16%
Dynamics
13%
Conformation
13%
Hydrogen Bond
12%
Enzyme Active Site
12%
Spectroscopy
12%
Active Site
11%
Oncogene Src
10%
Conformational Change
10%
Mouse
9%
Small Molecule
9%
Protein Kinase A
9%
Imatinib
9%
Binding Site
9%
Protein Kinase C
9%
Solution and Solubility
8%
SH3 Domain
8%
Guanylate Cyclase
8%
Sulfonic Acid
8%
Cyclin-Dependent Kinase
8%
Dimerization
8%
Energy Transfer
8%
Fluorescence Resonance Energy Transfer
8%
Tyrosine
7%
Myeloid
7%
Infrared Radiation
7%
Signal Transduction
5%
Keyphrases
Aurora Kinase A (AURKA)
39%
Cyclin-dependent Kinase 2 (CDK2)
32%
Aurora A
32%
Kinase Inhibitor
31%
Phosphorylation
26%
Electric Field (E-field)
24%
Activation Loop
23%
Protein Kinase
19%
Kinase Domain
19%
DFG-out
19%
Src Kinase
16%
C-terminal Src Kinase
16%
Tyrosine Kinase Domain
16%
Abl Tyrosine Kinase
16%
Bosutinib
16%
Hydrogen Bonds (H-bonds)
16%
Vibrational Stark Effect
14%
Cyclin
13%
Allosteric Coupling
13%
Allostery
12%
Active Sites
12%
C-Src
12%
Electric Field Measurement
12%
DFG Motif
11%
TPX2
10%
Allosteric Activation
10%
Hydrogen Bond Network
10%
Water-mediated Hydrogen Bonds
10%
Conformational Change
10%
Allosteric Inhibitor
10%
Kinase Activity
10%
Direct Measurement
10%
Kinase Inhibition
9%
Kinase Activation
9%
High Affinity
9%
Catalytic Domain
9%
Contraception
9%
Chronic Myeloid Leukemia
9%
Inhibitor Binding
8%
ATP Binding Site
8%
Infrared Frequencies
8%
Solvent-induced
8%
Experimental Quantification
8%
Aromatic Nitriles
8%
Solvatochromism
8%
Conformational Profiling
8%
Tyrosine Kinase C
8%
Allosteric Regulation
8%
T-loop Phosphorylation
8%
Lead Optimization
8%