Nicholas M Levinson

20062022
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

Phosphotransferases Medicine & Life Sciences
Aurora Kinase A Medicine & Life Sciences
Protein-Tyrosine Kinases Medicine & Life Sciences
Aurora Kinases Medicine & Life Sciences
Hydrogen Medicine & Life Sciences
Phosphorylation Chemical Compounds
Protein Kinases Medicine & Life Sciences
Hydrogen bonds Engineering & Materials Science

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Projects 2014 2022

Phosphotransferases
Fluorescence
Technology
Electrostatics
Binding Sites
Pharmaceutical Preparations

Research Output 2006 2019

1 Citation (Scopus)
Guanylate Cyclase
Catalytic Domain
Adenosine Triphosphate
Substrates
Phosphotransferases
14 Citations (Scopus)

A dynamic mechanism for allosteric activation of aurora kinase a by activation loop phosphorylation

Ruff, E. F., Muretta, J. M., Thompson, A. R., Lake, E. W., Cyphers, S., Albanese, S. K., Hanson, S. M., Behr, J. M., Thomas, D. D., Chodera, J. D. & Levinson, N. M., Feb 21 2018, In : eLife. 7, e32766.

Research output: Contribution to journalArticle

Aurora Kinases
Phosphorylation
Chemical activation
Protein Kinases
Phosphotransferases
1 Citation (Scopus)

An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression

Albanese, S. K., Parton, D. L., Işlk, M., Rodríguez-Laureano, L., Hanson, S. M., Behr, J. M., Gradia, S., Jeans, C., Levinson, N. M., Seeliger, M. A. & Chodera, J. D., Aug 7 2018, In : Biochemistry. 57, 31, p. 4675-4689 15 p.

Research output: Contribution to journalArticle

Open Access
Phosphotransferases
Phosphoric Monoester Hydrolases
Libraries
Bacteria
Adenosine Triphosphate
6 Citations (Scopus)

Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states

Lake, E. W., Muretta, J. M., Thompson, A. R., Rasmussen, D. M., Majumdar, A., Faber, E. B., Ruff, E. F., Thomas, D. D. & Levinson, N. M., Dec 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11894-E11903

Research output: Contribution to journalArticle

Open Access
Aurora Kinases
Phosphotransferases
Aurora Kinase A
Neuroblastoma
Protein Kinases
5 Citations (Scopus)

The multifaceted allosteric regulation of Aurora kinase A

Levinson, N. M., Jun 26 2018, In : Biochemical Journal. 475, 12, p. 2025-2042 18 p.

Research output: Contribution to journalReview article

Open Access
Aurora Kinase A
Allosteric Regulation
Protein Kinases
Phosphotransferases
Chemical activation