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Nicholas M Levinson

20062023

Research output per year

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Projects

Time-resolved FRET-based allostery sensors for any protein kinase drug target

Levinson, N. M., Drake, J. M., Georg, G. & Thomas, D. D.

NIH NATIONAL CANCER INSTITUTE (NCI)

3/1/20 → 2/28/23

Project: Research project

    • Decoding the dynamic mechanism of allosteric activation

    Levinson, N. M., Muretta, J. M. & Veglia, G.

    NIH NIGMS NATL INST OF GENERAL

    1/1/18 → 12/31/22

    Project: Research project

    • A novel time-resolved fluorescence-based high-throughput

    Levinson, N. M. & Muretta, J. M.

    NIH NATIONAL CANCER INSTITUTE (NCI)

    8/1/17 → 7/31/20

    Project: Research project

    • Kinome-Wide Spectroscopic Study of Drug Binding Site Ele

    Levinson, N. M.

    NIH NIGMS NATL INST OF GENERAL

    12/11/14 → 11/30/17

    Project: Research project

    • Research Output

    The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate

    Edmund, A. B., Walseth, T. F., Levinson, N. M. & Potter, L. R., Jan 29 2019, In : Science signaling. 12, 566, aau5378.

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    A dynamic mechanism for allosteric activation of aurora kinase a by activation loop phosphorylation

    Ruff, E. F., Muretta, J. M., Thompson, A. R., Lake, E. W., Cyphers, S., Albanese, S. K., Hanson, S. M., Behr, J. M., Thomas, D. D., Chodera, J. D. & Levinson, N. M., Feb 21 2018, In : eLife. 7, e32766.

    Research output: Contribution to journal › Article

    Open Access
    • 17 Scopus citations

    An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression

    Albanese, S. K., Parton, D. L., Işlk, M., Rodríguez-Laureano, L., Hanson, S. M., Behr, J. M., Gradia, S., Jeans, C., Levinson, N. M., Seeliger, M. A. & Chodera, J. D., Aug 7 2018, In : Biochemistry. 57, 31, p. 4675-4689 15 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states

    Lake, E. W., Muretta, J. M., Thompson, A. R., Rasmussen, D. M., Majumdar, A., Faber, E. B., Ruff, E. F., Thomas, D. D. & Levinson, N. M., Dec 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11894-E11903

    Research output: Contribution to journal › Article

    Open Access
    • 8 Scopus citations

    The multifaceted allosteric regulation of Aurora kinase A

    Levinson, N. M., Jun 26 2018, In : Biochemical Journal. 475, 12, p. 2025-2042 18 p.

    Research output: Contribution to journal › Review article

    Open Access
    • 6 Scopus citations