Projects per year
Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
Phosphotransferases
Medicine & Life Sciences
Aurora Kinase A
Medicine & Life Sciences
Protein-Tyrosine Kinases
Medicine & Life Sciences
Aurora Kinases
Medicine & Life Sciences
Hydrogen
Medicine & Life Sciences
Phosphorylation
Chemical Compounds
Protein Kinases
Medicine & Life Sciences
Hydrogen bonds
Engineering & Materials Science
Network
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Projects 2014 2022
Decoding the dynamic mechanism of allosteric activation
Levinson, N. M., Muretta, J. M. & Veglia, G.
NIH NIGMS NATL INST OF GENERAL
1/1/18 → 12/31/22
Project: Research project
Cyclin-Dependent Kinases
A novel time-resolved fluorescence-based high-throughput
Levinson, N. M. & Muretta, J. M.
NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/17 → 7/31/20
Project: Research project
Phosphotransferases
Fluorescence
Technology
Kinome-Wide Spectroscopic Study of Drug Binding Site Ele
NIH NIGMS NATL INST OF GENERAL
12/11/14 → 11/30/17
Project: Research project
Electrostatics
Binding Sites
Pharmaceutical Preparations
Research Output 2006 2019
3
Citations
(Scopus)
The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate
Edmund, A. B., Walseth, T. F., Levinson, N. M. & Potter, L. R., Jan 29 2019, In : Science Signaling. 12, 566, aau5378.Research output: Contribution to journal › Article
Guanylate Cyclase
Catalytic Domain
Adenosine Triphosphate
Substrates
Phosphotransferases
16
Citations
(Scopus)
A dynamic mechanism for allosteric activation of aurora kinase a by activation loop phosphorylation
Ruff, E. F., Muretta, J. M., Thompson, A. R., Lake, E. W., Cyphers, S., Albanese, S. K., Hanson, S. M., Behr, J. M., Thomas, D. D., Chodera, J. D. & Levinson, N. M., Feb 21 2018, In : eLife. 7, e32766.Research output: Contribution to journal › Article
Aurora Kinases
Phosphorylation
Chemical activation
Protein Kinases
Phosphotransferases
1
Citation
(Scopus)
An Open Library of Human Kinase Domain Constructs for Automated Bacterial Expression
Albanese, S. K., Parton, D. L., Işlk, M., Rodríguez-Laureano, L., Hanson, S. M., Behr, J. M., Gradia, S., Jeans, C., Levinson, N. M., Seeliger, M. A. & Chodera, J. D., Aug 7 2018, In : Biochemistry. 57, 31, p. 4675-4689 15 p.Research output: Contribution to journal › Article
Open Access
Phosphotransferases
Phosphoric Monoester Hydrolases
Libraries
Bacteria
Adenosine Triphosphate
7
Citations
(Scopus)
Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states
Lake, E. W., Muretta, J. M., Thompson, A. R., Rasmussen, D. M., Majumdar, A., Faber, E. B., Ruff, E. F., Thomas, D. D. & Levinson, N. M., Dec 18 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. E11894-E11903Research output: Contribution to journal › Article
Open Access
Aurora Kinases
Phosphotransferases
Aurora Kinase A
Neuroblastoma
Protein Kinases
6
Citations
(Scopus)
The multifaceted allosteric regulation of Aurora kinase A
Levinson, N. M., Jun 26 2018, In : Biochemical Journal. 475, 12, p. 2025-2042 18 p.Research output: Contribution to journal › Review article
Open Access
Aurora Kinase A
Allosteric Regulation
Protein Kinases
Phosphotransferases
Chemical activation