Neeraj K Mishra

20102020

Research output per year

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2019

Investigation of (S)-(-)-acidomycin: A selective antimycobacterial natural product that inhibits biotin synthase

Bockman, M. R., Engelhart, C. A., Cramer, J. D., Howe, M. D., Mishra, N. K., Zimmerman, M., Larson, P., Alvarez-Cabrera, N., Park, S. W., Boshoff, H. I. M., Bean, J. M., Young, V. G., Ferguson, D. M., Dartois, V., Jarrett, J. T., Schnappinger, D. & Aldrich, C., Apr 12 2019, In : ACS Infectious Diseases. 5, 4, p. 598-617 20 p.

Research output: Contribution to journalArticle

4 Scopus citations
2018

Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor

Divakaran, A., Talluri, S. K., Ayoub, A. M., Mishra, N. K., Cui, H., Widen, J. C., Berndt, N., Zhu, J. Y., Carlson, A. S., Topczewski, J. J., Schonbrunn, E. K., Harki, D. A. & Pomerantz, W. C. K., Oct 25 2018, In : Journal of medicinal chemistry. 61, 20, p. 9316-9334 19 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2017

Specific Acetylation Patterns of H2A.Z Form Transient Interactions with the BPTF Bromodomain

Perell, G. T., Mishra, N. K., Sudhamalla, B., Ycas, P. D., Islam, K. & Pomerantz, W. C. K., Sep 5 2017, In : Biochemistry. 56, 35, p. 4607-4615 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2016

Protein-observed 19F-NMR for fragment screening, affinity quantification and druggability assessment

Gee, C. T., Arntson, K. E., Urick, A. K., Mishra, N. K., Hawk, L., Wisniewski, A. J. & Pomerantz, W. C., Aug 1 2016, In : Nature Protocols. 11, 8, p. 1414-1427 14 p.

Research output: Contribution to journalArticle

45 Scopus citations
2015

Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules

Urick, A. K., Hawk, L. M. L., Cassel, M. K., Mishra, N. K., Liu, S., Adhikari, N., Zhang, W., Dos Santos, C. O., Hall, J. L. & Pomerantz, W. C. K., Oct 16 2015, In : ACS Chemical Biology. 10, 10, p. 2246-2256 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Molecular mechanisms and kinetic effects of FXYD1 and phosphomimetic mutants on purified human Na,K-ATPase

Mishra, N. K., Habeck, M., Kirchner, C., Haviv, H., Peleg, Y., Eisenstein, M., Apell, H. J. & Karlish, S. J. D., Nov 27 2015, In : Journal of Biological Chemistry. 290, 48, p. 28746-28759 14 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014

Fluorinated aromatic amino acids are sensitive 19 f NMR probes for bromodomain-ligand interactions

Mishra, N. K., Urick, A. K., Ember, S. W. J., Schonbrunn, E. & Pomerantz, W. C., Dec 19 2014, In : ACS Chemical Biology. 9, 12, p. 2755-2760 6 p.

Research output: Contribution to journalArticle

44 Scopus citations
2012

Polyol osmolytes stabilize native-like cooperative intermediate state of yeast hexokinase A at low pH

Devaraneni, P. K., Mishra, N. & Bhat, R., Apr 1 2012, In : Biochimie. 94, 4, p. 947-952 6 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

FXYD proteins stabilize Na,K-ATpase: Amplification of specific phosphatidylserine-protein interactions

Mishra, N. K., Peleg, Y., Cirri, E., Belogus, T., Lifshitz, Y., Voelker, D. R., Apell, H. J., Garty, H. & Karlish, S. J. D., Mar 18 2011, In : Journal of Biological Chemistry. 286, 11, p. 9699-9712 14 p.

Research output: Contribution to journalArticle

55 Scopus citations

Phospholemman (FXYD1) raises the affinity of the human α 1β1 isoform of Na,K-ATPase for Na ions

Cirri, E., Katz, A., Mishra, N. K., Belogus, T., Lifshitz, Y., Garty, H., Karlish, S. J. D. & Apell, H. J., May 10 2011, In : Biochemistry. 50, 18, p. 3736-3748 13 p.

Research output: Contribution to journalArticle

11 Scopus citations
2010

Characterization of the active site and coenzyme binding pocket of the monomeric UDP- galactose 4'- epimerase of Aeromonas hydrophila

Agarwal, S., Mishra, N., Agarwal, S. & Dixit, A., 2010, In : BMB Reports. 43, 6, p. 419-426 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

PemK toxin of Bacillus anthracis is a ribonuclease: An insight into its active site, structure, and function

Agarwal, S., Mishra, N. K., Bhatnagar, S. & Bhatnagar, R., Mar 5 2010, In : Journal of Biological Chemistry. 285, 10, p. 7254-7270 17 p.

Research output: Contribution to journalArticle

44 Scopus citations