Nasra H Giama

20122020

Research output per year

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Research Output

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Article

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 690-705.e9

Research output: Contribution to journalArticle

Open Access
109 Scopus citations

A model predicting short-term mortality in patients with advanced liver cirrhosis and concomitant infection

Li, Y., Chaiteerakij, R., Kwon, J. H., Jang, J. W., Lee, H. L., Cha, S., Ding, X. W., Thongprayoon, C., Ha, F. S., Nie, C. Y., Zhang, Q., Yang, Z., Giama, N. H., Roberts, L. R. & Han, T., Oct 1 2018, In : Medicine (United States). 97, 41, e12758.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 400-416.e11

Research output: Contribution to journalArticle

Open Access
304 Scopus citations

Anti-viral therapy is associated with improved survival but is underutilised in patients with hepatitis B virus-related hepatocellular carcinoma: real-world east and west experience

Chen, V. L., Yeh, M. L., Le, A. K., Jun, M., Saeed, W. K., Yang, J. D., Huang, C. F., Lee, H. Y., Tsai, P. C., Lee, M. H., Giama, N., Kim, N. G., Nguyen, P. P., Dang, H., Ali, H. A., Zhang, N., Huang, J. F., Dai, C. Y., Chuang, W. L., Roberts, L. R. & 4 others, Jun, D. W., Lim, Y. S., Yu, M. L. & Nguyen, M. H., Jul 2018, In : Alimentary Pharmacology and Therapeutics. 48, 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 386-399.e12

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

The Cancer Genome Atlas Research Network, Oct 24 2018, In : Cell Systems. 7, 4, p. 422-437.e7

Research output: Contribution to journalArticle

Open Access
30 Scopus citations

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

Chaiteerakij, R., Juran, B. D., Aboelsoud, M. M., Harmsen, W. S., Moser, C. D., Giama, N. H., Allotey, L. K., Mettler, T. A., Baichoo, E., Zhang, X., Therneau, T. M., Lazaridis, K. N. & Roberts, L. R., Oct 2015, In : Cancer medicine. 4, 10, p. 1599-1602 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

Barriers in Hepatitis C Treatment in Somali Patients in the Direct Acting Antiviral Therapy Era

Elwir, S., Anugwom, C., Connor, E. K., Giama, N. H., Ndzengue, A., Menk, J., Mohamed, E. A., Roberts, L. R. & Hassan, M., Dec 2018, In : Journal of the National Medical Association. 110, 6, p. 556-559 4 p.

Research output: Contribution to journalArticle

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

The Cancer Genome Atlas Network, Apr 5 2018, In : Cell. 173, 2, p. 291-304.e6

Research output: Contribution to journalArticle

Open Access
297 Scopus citations

Circulating tumor cells are associated with poor overall survival in patients with cholangiocarcinoma

Yang, J. D., Campion, M. B., Liu, M. C., Chaiteerakij, R., Giama, N. H., Ahmed Mohammed, H., Zhang, X., Hu, C., Campion, V. L., Jen, J., Venkatesh, S. K., Halling, K. C., Kipp, B. R. & Roberts, L. R., Jan 1 2016, In : Hepatology. 63, 1, p. 148-158 11 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

Clinical Features Associated with Survival Outcome in African-American Patients with Hepatocellular Carcinoma

Estevez, J., Yang, J. D., Leong, J., Nguyen, P., Giama, N. H., Zhang, N., Ali, H. A., Lee, M. H., Cheung, R., Roberts, L., Schwartz, M. & Nguyen, M. H., Jan 1 2019, In : American Journal of Gastroenterology. 114, 1, p. 80-88 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Combinations of biomarkers and Milan criteria for predicting hepatocellular carcinoma recurrence after liver transplantation

Chaiteerakij, R., Zhang, X., Addissie, B. D., Mohamed, E. A., Harmsen, W. S., Theobald, P. J., Peters, B. E., Balsanek, J. G., Ward, M. M., Giama, N. H., Moser, C. D., Oseini, A. M., Umeda, N., Venkatesh, S., Harnois, D. M., Charlton, M. R., Yamada, H., Satomura, S., Algeciras-Schimnich, A., Snyder, M. R. & 2 others, Therneau, T. M. & Roberts, L. R., May 1 2015, In : Liver Transplantation. 21, 5, p. 599-606 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 721-735.e8

Research output: Contribution to journalArticle

Open Access
85 Scopus citations

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

The Cancer Genome Atlas Research Network, Aug 13 2018, In : Cancer Cell. 34, 2, p. 211-224.e6

Research output: Contribution to journalArticle

Open Access
124 Scopus citations

Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

Ally, A., Balasundaram, M., Carlsen, R., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Cheung, D., Wong, T. & 31 others, Brooks, D., Robertson, A. G., Bowlby, R., Mungall, K., Sadeghi, S., Xi, L., Covington, K., Shinbrot, E., Wheeler, D. A., Gibbs, R. A., Donehower, L. A., Wang, L., Bowen, J., Gastier-Foster, J. M., Gerken, M., Helsel, C., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Wise, L., Zmuda, E., Gabriel, S. B., Meyerson, M., Cibulskis, C., Murray, B. A., Shih, J., Beroukhim, R., Cherniack, A. D., Schumacher, S. E., Giama, N. H. & The Cancer Genome Atlas Research Network, Jun 15 2017, In : Cell. 169, 7, p. 1327-1341.e23

Research output: Contribution to journalArticle

Open Access
475 Scopus citations

Comprehensive Characterization of Cancer Driver Genes and Mutations

The MC3 Working Group & The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 371-385.e18

Research output: Contribution to journalArticle

Open Access
350 Scopus citations

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

The Cancer Genome Atlas Research Network, Oct 30 2018, In : Cell reports. 25, 5, p. 1304-1317.e5

Research output: Contribution to journalArticle

Open Access
45 Scopus citations

Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

The Fusion Analysis Working Group & The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 227-238.e3

Research output: Contribution to journalArticle

Open Access
106 Scopus citations

Factors Influencing Surveillance for Hepatocellular Carcinoma in Patients with Liver Cirrhosis

Ahmed Mohammed, H. A., Yang, J. D., Giama, N. H., Choi, J., Ali, H. M., Mara, K. C., Harmsen, W. S., Wiesner, R. H., Leise, M. D., Therneau, T. M. & Roberts, L. R., Feb 1 2017, In : Liver Cancer. 6, 2, p. 126-136 11 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

GALAD score for hepatocellular carcinoma detection in comparison with liver ultrasound and proposal of Galadus score

Yang, J. D., Addissie, B. D., Mara, K. C., Harmsen, W. S., Dai, J., Zhang, N., Wongjarupong, N., Ali, H. M., Ali, H. A., Hassan, F. A., Lavu, S., Cvinar, J. L., Giama, N. H., Moser, C. D., Miyabe, K., Allotey, L. K., Algeciras-Schimnich, A., Theobald, J. P., Ward, M. M., Nguyen, M. H. & 11 others, Befeler, A. S., Reddy, K. R., Schwartz, M., Harnois, D. M., Yamada, H., Srivastava, S., Rinaudo, J. A., Gores, G. J., Feng, Z., Marrero, J. A. & Roberts, L. R., Mar 2019, In : Cancer Epidemiology Biomarkers and Prevention. 28, 3, p. 531-538 8 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Genome-wide discovery and validation of diagnostic DNA methylation-based biomarkers for hepatocellular cancer detection in circulating cell free DNA

Hlady, R. A., Zhao, X., Pan, X., Dong Yang, J., Ahmed, F., Antwi, S. O., Giama, N. H., Patel, T., Roberts, L. R., Liu, C. & Robertson, K. D., Jan 1 2019, In : Theranostics. 9, 24, p. 7239-7250 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 194-212.e6

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 676-689.e3

Research output: Contribution to journalArticle

Open Access
116 Scopus citations

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 239-254.e6

Research output: Contribution to journalArticle

Open Access
154 Scopus citations

Hepatocellular Carcinoma Detection by Plasma Methylated DNA: Discovery, Phase I Pilot, and Phase II Clinical Validation

Kisiel, J. B., Dukek, B. A., V.S.R. Kanipakam, R., Ghoz, H. M., Yab, T. C., Berger, C. K., Taylor, W. R., Foote, P. H., Giama, N. H., Onyirioha, K., Abdallah, M. A., Burger, K. N., Slettedahl, S. W., Mahoney, D. W., Smyrk, T. C., Lewis, J. T., Giakoumopoulos, M., Allawi, H. T., Lidgard, G. P., Roberts, L. R. & 1 others, Ahlquist, D. A., Mar 2019, In : Hepatology. 69, 3, p. 1180-1192 13 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Hypothyroidism is associated with worse outcomes of hepatocellular carcinoma patients after liver transplantation

Zhang, N., Jin, W., Zhou, S., Yang, J. D., Harmsen, W. S., Giama, N. H., Wongjarupong, N., Heimbach, J. K., Watt, K. D., Malhi, H., Therneau, T. M. & Roberts, L. R., Dec 2018, In : Cancer medicine. 7, 12, p. 5870-5878 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Identification of fucosylated Fetuin-A as a potential biomarker for cholangiocarcinoma

Betesh, L., Comunale, M. A., Wang, M., Liang, H., Hafner, J., Karabudak, A., Giama, N. H., Moser, C. D., Miyoshi, E., Roberts, L. R., Block, T. M. & Mehta, A., Sep 2017, In : Proteomics - Clinical Applications. 11, 9-10, 1600141.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 213-226.e3

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

CONSORTIA, Mar 14 2017, In : Cell reports. 18, 11, p. 2780-2794 15 p.

Research output: Contribution to journalArticle

Open Access
122 Scopus citations

Knowledge, Attitudes, and Behaviors of Viral Hepatitis Among Recent African Immigrants in the United States: A Community Based Participatory Research Qualitative Study

Mohamed, E. A., Giama, N. H., Shaleh, H. M., Kerandi, L., Oseini, A. M., Ahmed Mohammed, H., Kerandi, H., Allotey, L. K., Waaeys, I. A., Ali, H. A., Ali, H. M., Mohamed, S. A., Yang, J. D., Gaga, W. O., Tamire, L. L., Windissa, A., Patten, C. A., Balls-Berry, J. E. & Roberts, L. R., Mar 6 2020, In : Frontiers in Public Health. 8, 25.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

The Cancer Genome Atlas Research Network, Apr 9 2018, In : Cancer Cell. 33, 4, p. 706-720.e9

Research output: Contribution to journalArticle

Open Access
146 Scopus citations

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 172-180.e3

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 338-354.e15

Research output: Contribution to journalArticle

Open Access
161 Scopus citations

Metformin does not improve survival in patients with hepatocellular carcinoma

Bhat, M., Chaiteerakij, R., Harmsen, W. S., Schleck, C. D., Yang, J. D., Giama, N. H., Therneau, T. M., Gores, G. J. & Roberts, L. R., Nov 14 2014, In : World journal of gastroenterology. 20, 42, p. 15750-15755 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 255-269.e4

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

More advanced disease and worse survival in cryptogenic compared to viral hepatocellular carcinoma

Jun, T. W., Yeh, M. L., Yang, J. D., Chen, V. L., Nguyen, P., Giama, N. H., Huang, C. F., Hsing, A. W., Dai, C. Y., Huang, J. F., Chuang, W. L., Roberts, L. R., Yu, M. L. & Nguyen, M. H., May 2018, In : Liver International. 38, 5, p. 895-902 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Novel Deleterious Dihydropyrimidine Dehydrogenase Variants May Contribute to 5-Fluorouracil Sensitivity in an East African Population

Elraiyah, T., Jerde, C. R., Shrestha, S., Wu, R., Nie, Q., Giama, N. H., Sarangi, V., Roberts, L. R., Offer, S. M. & Diasio, R. B., Mar 1 2017, In : Clinical pharmacology and therapeutics. 101, 3, p. 382-390 9 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Oncogenic Signaling Pathways in The Cancer Genome Atlas

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 321-337.e10

Research output: Contribution to journalArticle

Open Access
397 Scopus citations

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

The Cancer Genome Atlas Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 282-300.e2

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 297-312.e12

Research output: Contribution to journalArticle

Open Access
92 Scopus citations

Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Campbell, P. J., Getz, G., Korbel, J. O., Stuart, J. M., Jennings, J. L., Stein, L. D., Perry, M. D., Nahal-Bose, H. K., Ouellette, B. F. F., Li, C. H., Rheinbay, E., Nielsen, G. P., Sgroi, D. C., Wu, C. L., Faquin, W. C., Deshpande, V., Boutros, P. C., Lazar, A. J., Hoadley, K. A. & 31 others, Louis, D. N., Dursi, L. J., Yung, C. K., Bailey, M. H., Saksena, G., Raine, K. M., Buchhalter, I., Kleinheinz, K., Schlesner, M., Zhang, J., Wang, W., Wheeler, D. A., Ding, L., Simpson, J. T., O’Connor, B. D., Yakneen, S., Zhang, F., Johnson, T. A., Huang, Y., Lee, D., Wang, Q., Yang, F., Yang, Y., Brewer, D. S., Wood, S., Anderson, M. J., Li, L., Xiao, X., López, C., Giama, N. H. & Winterhoff, B., Feb 6 2020, In : Nature. 578, 7793, p. 82-93 12 p.

Research output: Contribution to journalArticle

Open Access
100 Scopus citations

Pathogenic Germline Variants in 10,389 Adult Cancers

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 355-370.e14

Research output: Contribution to journalArticle

Open Access
153 Scopus citations

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

The Cancer Genome Atlas Research Network, Apr 5 2018, In : Cell. 173, 2, p. 305-320.e10

Research output: Contribution to journalArticle

Open Access
82 Scopus citations

Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In : Cell Systems. 6, 3, p. 271-281.e7

Research output: Contribution to journalArticle

Open Access
114 Scopus citations

Silent Tyrosinemia Type I Without Elevated Tyrosine or Succinylacetone Associated with Liver Cirrhosis and Hepatocellular Carcinoma

Blackburn, P. R., Hickey, R. D., Nace, R. A., Giama, N. H., Kraft, D. L., Bordner, A. J., Chaiteerakij, R., McCormick, J. B., Radulovic, M., Graham, R. P., Torbenson, M. S., Tortorelli, S., Scott, C. R., Lindor, N. M., Milliner, D. S., Oglesbee, D., Al-Qabandi, W., Grompe, M., Gavrilov, D. K., El-Youssef, M. & 5 others, Clark, K. J., Atwal, P. S., Roberts, L. R., Klee, E. W. & Ekker, S. C., Oct 1 2016, In : Human mutation. 37, 10, p. 1097-1105 9 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 282-296.e4

Research output: Contribution to journalArticle

Open Access
81 Scopus citations

Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 181-193.e7

Research output: Contribution to journalArticle

Open Access
121 Scopus citations

Systematic Analysis of Splice-Site-Creating Mutations in Cancer

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 270-281.e3

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

The Cancer Genome Atlas Research Network, Apr 3 2018, In : Cell reports. 23, 1, p. 313-326.e5

Research output: Contribution to journalArticle

Open Access
117 Scopus citations

The Immune Landscape of Cancer

The Cancer Genome Atlas Research Network, Apr 17 2018, In : Immunity. 48, 4, p. 812-830.e14

Research output: Contribution to journalArticle

Open Access
565 Scopus citations