Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
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Projects
- 10 Finished
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Genetic mechanisms of Mitotic DNA synthesis in mammalian cells
Shima, N. (PI), Bielinsky, A. K. (CoI) & Sobeck, A. (CoI)
NIH NIGMS NATL INST OF GENERAL
9/1/20 → 6/30/25
Project: Research project
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Functional crosstalk between the Fanconi Anemia and ATRX/DAXX histone chaperone pathways
Yong, J. (PI), Shima, N. (CoI) & Sobeck, A. (Prior Principal Investigator)
NIH NIGMS NATL INST OF GENERAL
5/1/19 → 4/30/24
Project: Research project
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Targeting mitotic DNA synthesis for selective killing of
Shima, N. (PI)
4/1/18 → 3/31/21
Project: Research project
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A role of dormant origins in promoting accurate bypass o
Shima, N. (PI)
NIH NATIONAL INST OF ENVIRON HEALTH SCI
9/15/17 → 8/31/20
Project: Research project
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Exploiting replication stress for the selective killing
Shima, N. (PI)
4/1/15 → 3/31/18
Project: Research project
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FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
Leung, W., Baxley, R. M., Traband, E., Chang, Y. C., Rogers, C. B., Wang, L., Durrett, W., Bromley, K. S., Fiedorowicz, L., Thakar, T., Tella, A., Sobeck, A., Hendrickson, E. A., Moldovan, G. L., Shima, N. & Bielinsky, A. K., Dec 26 2023, In: Cell reports. 42, 12, 113523.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Mitotic DNA Synthesis in Untransformed Human Cells Preserves Common Fragile Site Stability via a FANCD2-Driven Mechanism That Requires HELQ
Traband, E. L., Hammerlund, S. R., Shameem, M., Narayan, A., Ramana, S., Tella, A., Sobeck, A. & Shima, N., Nov 15 2023, In: Journal of Molecular Biology. 435, 22, 168294.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Mitotic DNA synthesis is differentially regulated between cancer and noncancerous cells
Graber-Feesl, C. L., Pederson, K. D., Aney, K. J. & Shima, N., Aug 1 2019, In: Molecular Cancer Research. 17, 8, p. 1687-1698 12 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development
Shima, N. & Pederson, K. D., Aug 2017, In: DNA Repair. 56, p. 166-173 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access19 Scopus citations -
Embryonic Stem Cells License a High Level of Dormant Origins to Protect the Genome against Replication Stress
Ge, X. Q., Han, J., Cheng, E. C., Yamaguchi, S., Shima, N., Thomas, J. L. & Lin, H., 2015, In: Stem Cell Reports. 5, 2, p. 185-194 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations