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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Genetic mechanisms of Mitotic DNA synthesis in mammalian cells
Shima, N., Bielinsky, A. K. & Sobeck, A.
NIH NIGMS NATL INST OF GENERAL
9/1/20 → 6/30/24
Project: Research project
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Functional crosstalk between the Fanconi Anemia and ATRX/DAXX histone chaperone pathways
NIH NIGMS NATL INST OF GENERAL
5/1/19 → 4/30/23
Project: Research project
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Targeting mitotic DNA synthesis for selective killing of
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/18 → 3/31/21
Project: Research project
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A role of dormant origins in promoting accurate bypass o
NIH NATL INST OF ENVIRON HEALTH SCIENCES
9/15/17 → 8/31/20
Project: Research project
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Exploiting replication stress for the selective killing
NIH NATIONAL CANCER INSTITUTE (NCI)
4/1/15 → 3/31/18
Project: Research project
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Mitotic DNA synthesis is differentially regulated between cancer and noncancerous cells
Graber-Feesl, C. L., Pederson, K. D., Aney, K. J. & Shima, N., Aug 1 2019, In: Molecular Cancer Research. 17, 8, p. 1687-1698 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Dormant origins as a built-in safeguard in eukaryotic DNA replication against genome instability and disease development
Shima, N. & Pederson, K. D., Aug 2017, In: DNA Repair. 56, p. 166-173 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access13 Scopus citations -
Embryonic Stem Cells License a High Level of Dormant Origins to Protect the Genome against Replication Stress
Ge, X. Q., Han, J., Cheng, E. C., Yamaguchi, S., Shima, N., Thomas, J. L. & Lin, H., 2015, In: Stem Cell Reports. 5, 2, p. 185-194 10 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression
Luebben, S. W., Kawabata, T., Johnson, C. S., O'sullivan, M. G. & Shima, N., May 2014, In: Nucleic acids research. 42, 9, p. 5605-5615 11 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling
Luo, Y., Hartford, S. A., Zeng, R., Southard, T. L., Shima, N. & Schimenti, J. C., Jul 2014, In: PLoS genetics. 10, 7, e1004471.Research output: Contribution to journal › Article › peer-review
42 Scopus citations