Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Targeting p21-Highly Expressing Cells to Increase Lifespan and Healthspan in Old Age
Xu, M. (PI), Guo, C. (Other Role), Wang, B. (Other Role), Wu, R. (Other Role) & Yan, P. (Other Role)
NIH NATIONAL INSTITUTE ON AGING
8/1/25 → 2/28/27
Project: Research project
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The synergistic benefits of metformin and senolytics on lifespan and healthspan
Xu, M. (PI), Guo, C. (Other Role), Wang, B. (Other Role) & Yan, P. (Other Role)
AMERICAN FEDERATION FOR AGING RESEARCH
12/16/24 → 12/31/26
Project: Research project
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Midwest Murine-Tissue Mapping Center (MM-TMC)
Beckman, K. B. (PI), Dong, X. (PI), Hwang, J. (PI), Niedernhofer, L. J. (PI), Pengo, T. (PI), Robbins, P. D. (PI), Sanders, M. A. (PI), Seelig, D. (PI), Temiz, N. A. (PI), Wang, J. (PI), Adeyi, O. (CoI), Aliferis, MD, PhD, C. (CoI), Bartolomucci, A. (CoI), Bernlohr, D. A. (CoI), Butterick, T. A. (CoI), Camell, C. (CoI), Garbe, J. R. (CoI), Griffin, T. J. (CoI), Ikramuddin, S. (CoI), Mashek, D. (CoI), Nelson, A. C. (CoI), Revelo, X. (CoI), Sarver, A. L. (CoI), Sun, R. (CoI), Walmsley, S. J. (CoI), Williams, J. W. (CoI) & Xu, M. (Co-Principal Investigator)
NIH NATIONAL INSTITUTE ON AGING
8/2/22 → 7/31/27
Project: Research project
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Targeting P21 positive senescent cells for alleviating TMJ degeneration
Xu, M. (PI)
UNIVERSITY OF NEBRASKA MEDICAL CENTER, NIH NIDCR NATL INST OF DENTAL
8/1/25 → 1/24/26
Project: Research project
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Targeting p21-positive Senescent Cells in vivo for Alleviating Metabolic and Physical Dysfunction
Xu, M. (PI), Guo, C. (Other Role), Wang, B. (Other Role), Wu, R. (Other Role) & Yan, P. (Other Role)
NIH NATIONAL INSTITUTE ON AGING
7/15/25 → 3/31/26
Project: Research project
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Biological Aging Acceleration in Major Depressive Disorder: A Multi-Omics Analysis
Diniz, B. S., Zhao, S., Drouard, G., Vuoksimaa, E., Ollikainen, M., Lenze, E. J., Xu, M., Fortinsky, R. H., Kuchel, G. A., Kaprio, J. & Kuo, C. L., Jan 2026, In: Aging cell. 25, 1, e70310.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
Fluorescence-Guided Spatial Mapping of p21-Expressing Senescent Cells in Aged Liver at Single-Cell Resolution
Hsu, J. E., Wang, B., Hwang, Y., Cheng, W., Zhao, Q., Si, Y., Xu, M., Kang, H. M. & Lee, J. H., Apr 2026, In: Biomolecules. 16, 4, 579.Research output: Contribution to journal › Article › peer-review
Open Access -
Past, present and future perspectives on the science of aging
Ambrosio, F., Artyomov, M. N., Austad, S. N., Barzilai, N., Belmonte, J. C. I., Belsky, D. W., Benayoun, B. A., Brunet, A., Dönertaş, H. M., Dubal, D. B., Fang, E. F., Feige, J. N., Fried, L. P., Furman, D., Gao, X., Gladyshev, V. N., Gorbunova, V., Gorospe, M., Han, J. D. J. & Hansson, O. & 33 others, , Jan 2026, In: Nature Aging. 6, 1, p. 6-22 17 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Premature aging in serious mental illness
Diniz, B. S., Fries, G. R., Kuo, C. L., Xu, M. & Lenze, E. J., 2026, (Accepted/In press) In: Neuropsychopharmacology.Research output: Contribution to journal › Review article › peer-review
5 Link opens in a new tab Scopus citations -
Senescent cell heterogeneity: origins, detection, and therapeutic implications
Wu, R., Zhu, J., Kim, H. & Xu, M., Sep 2026, In: Trends in Cell Biology. 36, 9, p. 794-804 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Link opens in a new tab Scopus citations