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Molecular mechanisms underlying FSHD Identification of genetic regulators of satellite cell biology

1997 …2024
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Research Output 1997 2019

2019

A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death

Bosnakovski, D., da Silva, M. T., Sunny, S. T., Ener, E. T., Toso, E. A., Yuan, C., Cui, Z., Walters, M. A., Jadhav, A. & Kyba, M., Sep 11 2019, In : Science advances. 5, 9, eaaw7781.

Research output: Contribution to journalArticle

Open Access
acetylation
gene expression
death
inhibitors
animal models
1 Citation (Scopus)

Estrogen Regulates the Satellite Cell Compartment in Females

Collins, B. C., Arpke, R. W., Larson, A. A., Baumann, C. W., Xie, N., Cabelka, C. A., Nash, N. L., Juppi, H. K., Laakkonen, E. K., Sipilä, S., Kovanen, V., Spangenburg, E. E., Kyba, M. & Lowe, D. A., Jul 9 2019, In : Cell reports. 28, 2, p. 368-381.e6

Research output: Contribution to journalArticle

Open Access
Muscle
Estrogens
Muscle Cells
Satellites
Stem Cells

Pluripotent Stem Cell-Based Therapeutics for Muscular Dystrophies

Selvaraj, S., Kyba, M. & Perlingeiro, R., Sep 1 2019, In : Trends in Molecular Medicine. 25, 9, p. 803-816 14 p.

Research output: Contribution to journalReview article

Pluripotent Stem Cells
Muscular Dystrophies
Autologous Transplantation
Therapeutics
Technology
5 Citations (Scopus)

Pluripotent stem cell-derived myogenic progenitors remodel their molecular signature upon in vivo engraftment

Incitti, T., Magli, A., Darabi, R., Yuan, C., Lin, K., Arpke, R. W., Azzag, K., Yamamoto, A., Stewart, R., Thomson, J. A., Kyba, M. & Perlingeiro, R. C. R., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 10, p. 4346-4351 6 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Myoblasts
Regeneration
Gene Expression Profiling
Muscular Diseases

Tet3 regulates cellular identity and DNA methylation in neural progenitor cells

Santiago, M., Antunes, C., Guedes, M., Iacovino, M., Kyba, M., Reik, W., Sousa, N., Pinto, L., Branco, M. R. & Marques, C. J., Jan 1 2019, (Accepted/In press) In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalArticle

DNA Methylation
Stem Cells
5-Methylcytosine
Genes
Neural Stem Cells
2018
5 Citations (Scopus)

A moderate oestradiol level enhances neutrophil number and activity in muscle after traumatic injury but strength recovery is accelerated

Le, G. C., Novotny, S. A., Mader, T. L., Greising, S., Chan, S., Kyba, M., Lowe, D. A. & Warren, G. L., Oct 1 2018, In : Journal of Physiology. 596, 19, p. 4665-4680 16 p.

Research output: Contribution to journalArticle

Open Access
Estradiol
Estrogens
Neutrophils
Muscles
Wounds and Injuries
1 Citation (Scopus)

Comment on structural basis of DUX4/IGH-driven transactivation

Aihara, H., Shi, K., Lee, J. K., Bosnakovski, D. & Kyba, M., Sep 1 2018, In : Leukemia. 32, 9, p. 2090-2092 3 p.

Research output: Contribution to journalLetter

Open Access
Transcriptional Activation
2 Citations (Scopus)

Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA

Lee, J. K., Bosnakovski, D., Toso, E. A., Dinh, T., Banerjee, S., Bohl, T. E., Shi, K., Orellana, K., Kyba, M. & Aihara, H., Dec 11 2018, In : Cell reports. 25, 11, p. 2955-2962.e3

Research output: Contribution to journalArticle

Facioscapulohumeral Muscular Dystrophy
Primates
Crystal structure
DNA
arginine glutamate
19 Citations (Scopus)

DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells

Gu, T., Lin, X., Cullen, S. M., Luo, M., Jeong, M., Estecio, M., Shen, J., Hardikar, S., Sun, D., Su, J., Rux, D., Guzman, A., Lee, M., Qi, L. S., Chen, J. J., Kyba, M., Huang, Y., Chen, T., Li, W. & Goodell, M. A., Jul 12 2018, In : Genome biology. 19, 1, 88.

Research output: Contribution to journalArticle

Open Access
embryonic stem cells
Epigenomics
epigenetics
canyons
DNA methylation
Open Access
HTML
Organized Financing
pathology
Pathology
muscles
6 Citations (Scopus)

Evolutionarily conserved Tbx5-Wnt2/2b pathway orchestrates cardiopulmonary development

Steimle, J. D., Rankin, S. A., Slagle, C. E., Bekeny, J., Rydeen, A. B., Chan, S. S. K., Kweon, J., Yang, X. H., Ikegami, K., Nadadur, R. D., Rowton, M., Hoffmann, A. D., Lazarevic, S., Thomas, W., Boyle Anderson, E. A. T., Horb, M. E., Luna-Zurita, L., Ho, R. K., Kyba, M., Jensen, B. & 3 others, Zorn, A. M., Conlon, F. L. & Moskowitz, I. P., Nov 6 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10615-E10624

Research output: Contribution to journalArticle

Mesoderm
Lung
Endoderm
Morphogenesis
Atrial Septum
1 Citation (Scopus)

Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression

Bosnakovski, D., Gearhart, M. D., Toso, E. A., Ener, E. T., Choi, S. H. & Kyba, M., Dec 1 2018, In : Scientific reports. 8, 1, 16957.

Research output: Contribution to journalArticle

Open Access
Muscle Development
Gene Expression
Myoblasts
Facioscapulohumeral Muscular Dystrophy
Genes
5 Citations (Scopus)

Mouse models of two missense mutations in actin-binding domain 1 of dystrophin associated with duchenne or becker muscular dystrophy

McCourt, J. L., Talsness, D. M., Lindsay, A., Arpke, R. W., Chatterton, P. D., Nelson, D. M., Chamberlain, C. M., Olthoff, J. T., Belanto, J. J., McCourt, P. M., Kyba, M., Lowe, D. A. & Ervasti, J. M., Feb 1 2018, In : Human molecular genetics. 27, 3, p. 451-462 12 p.

Research output: Contribution to journalArticle

Open Access
Dystrophin
Duchenne Muscular Dystrophy
Missense Mutation
Actins
Proteasome Endopeptidase Complex
6 Citations (Scopus)

Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity

Chan, S., Arpke, R. W., Filareto, A., Xie, N., Pappas, M. P., Penaloza, J. S., Perlingeiro, R. & Kyba, M., Jul 5 2018, In : Cell Stem Cell. 23, 1, p. 74-85.e6

Research output: Contribution to journalArticle

Teratoma
Muscle Cells
Skeletal Muscle
Stem Cells
Pluripotent Stem Cells
20 Citations (Scopus)

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction

Park, J-M., Seo, M., Jung, C. H., Grunwald, D., Stone, M., Otto, N. M., Toso, E., Ahn, Y., Kyba, M., Griffin, T. J., Higgins, L. & Kim, D-H., Apr 3 2018, In : Autophagy. 14, 4, p. 584-597 14 p.

Research output: Contribution to journalArticle

Open Access
Autophagy
Phosphotransferases
Phosphorylation
Starvation
Amino Acids
2017
4 Citations (Scopus)

A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion

Jiang, Y., Berry, D. C., Jo, A., Tang, W., Arpke, R. W., Kyba, M. & Graff, J. M., Jun 26 2017, In : Nature communications. 8, 15926.

Research output: Contribution to journalArticle

Open Access
Peroxisome Proliferator-Activated Receptors
Cell Communication
Vascular Endothelial Growth Factor A
cascades
Stem Cells
37 Citations (Scopus)

Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans

Berry, D. C., Jiang, Y., Arpke, R. W., Close, E. L., Uchida, A., Reading, D., Berglund, E. D., Kyba, M. & Graff, J. M., Jan 10 2017, In : Cell Metabolism. 25, 1, p. 166-181 16 p.

Research output: Contribution to journalArticle

Open Access
Cell Aging
Stem Cells
White Adipose Tissue
Therapeutic Uses
p38 Mitogen-Activated Protein Kinases
9 Citations (Scopus)

Erratum: Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans (Cell Metabolism (2017) 25(1) (166–181) (S1550413116305551)(10.1016/j.cmet.2016.10.023))

Berry, D. C., Jiang, Y., Arpke, R. W., Close, E. L., Uchida, A., Reading, D., Berglund, E. D., Kyba, M. & Graff, J. M., Feb 7 2017, In : Cell Metabolism. 25, 2, 1 p.

Research output: Contribution to journalComment/debate

Manuscripts
Cell Aging
Staining and Labeling
Beige Adipocytes
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole
11 Citations (Scopus)

Expansion and Purification Are Critical for the Therapeutic Application of Pluripotent Stem Cell-Derived Myogenic Progenitors

Kim, J., Magli, A., Chan, S. S. K., Oliveira, V. K. P., Wu, J., Darabi, R., Kyba, M. & Perlingeiro, R. C. R., Jul 11 2017, In : Stem Cell Reports. 9, 1, p. 12-22 11 p.

Research output: Contribution to journalArticle

Open Access
Pluripotent Stem Cells
Stem cells
Purification
Muscle
Scalability
16 Citations (Scopus)

MIR-125b promotes MLL-AF9-driven murine acute myeloid leukemia involving a VEGFA-mediated non-cell-intrinsic mechanism

Liu, J., Guo, B., Chen, Z., Wang, N., Iacovino, M., Cheng, J., Roden, C., Pan, W., Khan, S., Chen, S., Kyba, M., Fan, R., Guo, S. & Lu, J., Mar 16 2017, In : Blood. 129, 11, p. 1491-1502 12 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Acute Myeloid Leukemia
Leukemia
Stem cells
Hematopoiesis
2 Citations (Scopus)

Modulating the malignancy of hox proteins

Kyba, M., Jan 19 2017, In : Blood. 129, 3, p. 269-270 2 p.

Research output: Contribution to journalReview article

Open Access
Homeobox Genes
Proline
Blood
Transcription Factors
Genes
17 Citations (Scopus)

Muscle pathology from stochastic low level DUX4 expression in an FSHD mouse model

Bosnakovski, D., Chan, S. S. K., Recht, O. O., Hartweck, L. M., Gustafson, C. J., Athman, L. L., Lowe, D. A. & Kyba, M., Dec 1 2017, In : Nature communications. 8, 1, 550.

Research output: Contribution to journalArticle

Open Access
Facioscapulohumeral Muscular Dystrophy
pathology
Pathology
muscles
mice

Notch activation is required for downregulation of HoxA3-dependent endothelial cell phenotype during blood formation

Sanghez, V., Luzzi, A., Clarke, D., Kee, D., Beuder, S., Rux, D., Osawa, M., Madrenas, J., Chou, T. F., Kyba, M. & Iacovino, M., Oct 2017, In : PloS one. 12, 10, e0186818.

Research output: Contribution to journalArticle

Open Access
Endothelial cells
endothelial cells
Hemangioblasts
Blood
Down-Regulation
3 Citations (Scopus)

p53-independent DUX4 pathology in cell and animal models of facioscapulohumeral muscular dystrophy

Bosnakovski, D., Gearhart, M. D., Toso, E. A., Recht, O. O., Cucak, A., Jain, A. K., Barton, M. C. & Kyba, M., Oct 1 2017, In : DMM Disease Models and Mechanisms. 10, 10, p. 1211-1216 6 p.

Research output: Contribution to journalArticle

Open Access
Facioscapulohumeral Muscular Dystrophy
Pathology
Animals
Animal Models
Genes
9 Citations (Scopus)

Pax7 remodels the chromatin landscape in skeletal muscle stem cells

Lilja, K. C., Zhang, N., Magli, A., Gunduz, V., Bowman, C. J., Arpke, R. W., Darabi, R., Kyba, M., Perlingeiro, R. & Dynlacht, B. D., Apr 2017, In : PloS one. 12, 4, e0176190.

Research output: Contribution to journalArticle

Open Access
Stem cells
myocytes
Muscle Cells
Chromatin
chromatin
7 Citations (Scopus)

The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain

Bosnakovski, D., Toso, E. A., Hartweck, L. M., Magli, A., Lee, H. A., Thompson, E. R., Dandapat, A., Perlingeiro, R. C. R. & Kyba, M., Jan 1 2017, In : Journal of cell science. 130, 21, p. 3685-3697 13 p.

Research output: Contribution to journalArticle

Open Access
Homeodomain Proteins
Muscle Development
Facioscapulohumeral Muscular Dystrophy
Myoblasts
Transcriptional Activation
1 Citation (Scopus)

Twist of fate for skeletal muscle mesenchymal cells

Goloviznina, N. A. & Kyba, M., Mar 1 2017, In : Nature Cell Biology. 19, 3, p. 153-154 2 p.

Research output: Contribution to journalShort survey

Muscle Cells
Skeletal Muscle
Transcription Factors
2016
16 Citations (Scopus)

Development of Bipotent Cardiac/Skeletal Myogenic Progenitors from MESP1+ Mesoderm

Chan, S. S. K., Hagen, H. R., Swanson, S. A., Stewart, R., Boll, K. A., Aho, J., Thomson, J. A. & Kyba, M., Jan 12 2016, In : Stem Cell Reports. 6, 1, p. 26-34 9 p.

Research output: Contribution to journalArticle

Mesoderm
Muscle
Skeletal Muscle
Specifications
rho-Associated Kinases
20 Citations (Scopus)

DNA-binding sequence specificity of DUX4

Zhang, Y., Lee, J. K., Toso, E. A., Lee, J. S., Choi, S. H., Slattery, M., Aihara, H. & Kyba, M., Jan 28 2016, In : Skeletal Muscle. 6, 1, 8.

Research output: Contribution to journalArticle

Consensus Sequence
Transcriptional Activation
DNA
Facioscapulohumeral Muscular Dystrophy
Chromatin
35 Citations (Scopus)

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes

Choi, S. H., Gearhart, M. D., Cui, Z., Bosnakovski, D., Kim, M., Schennum, N. & Kyba, M., Jun 20 2016, In : Nucleic acids research. 44, 11, p. 5161-5173 13 p.

Research output: Contribution to journalArticle

Acetylation
Histones
Chromatin
Facioscapulohumeral Muscular Dystrophy
Histone Acetyltransferases
4 Citations (Scopus)

Flow cytometry and transplantation-based quantitative assays for satellite cell self-renewal and differentiation

Arpke, R. W. & Kyba, M., Jan 1 2016, Methods in Molecular Biology. Humana Press Inc., p. 163-179 17 p. (Methods in Molecular Biology; vol. 1460).

Research output: Chapter in Book/Report/Conference proceedingChapter

Flow Cytometry
Transplantation
Muscles
Transgenes
Cell Self Renewal
5 Citations (Scopus)

Freeze injury of the tibialis anterior muscle

Le, G., Lowe, D. A. & Kyba, M., Jan 1 2016, In : Methods in Molecular Biology. 1460, p. 33-41 9 p.

Research output: Contribution to journalArticle

Muscles
Wounds and Injuries
Muscle Cells
Skeletal Muscle
9 Citations (Scopus)

Germ cell nuclear factor (GCNF) represses Oct4 expression and globally modulates gene expression in human embryonic stem (hes) cells

Wang, H., Wang, X., Xu, X., Kyba, M. & Cooney, A. J., Apr 15 2016, In : Journal of Biological Chemistry. 291, 16, p. 8644-8652 9 p.

Research output: Contribution to journalArticle

Nuclear Receptor Subfamily 6, Group A, Member 1
Stem cells
Gene expression
Gene Expression
Genes
13 Citations (Scopus)

GSK3β inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells

Kitajima, K., Nakajima, M., Kanokoda, M., Kyba, M., Dandapat, A., Tolar, J., Saito, M. K., Toyoda, M., Umezawa, A. & Hara, T., Jan 1 2016, In : Experimental Hematology. 44, 1, p. 68-74.e10

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Pluripotent Stem Cells
Endothelial Cells
Cell Differentiation
Mesoderm
6 Citations (Scopus)

Heterogeneity of Mesp1+ mesoderm revealed by single-cell RNA-seq

Chan, S. S. K., Chan, H. H. W. & Kyba, M., Jun 3 2016, In : Biochemical and Biophysical Research Communications. 474, 3, p. 469-475 7 p.

Research output: Contribution to journalArticle

Mesoderm
Cells
RNA
Transcription Factors
Population
6 Citations (Scopus)

High frequency hearing loss and hyperactivity in DUX4 transgenic mice

Dandapat, A., Perrin, B. J., Cabelka, C., Razzoli, M., Ervasti, J. M., Bartolomucci, A., Lowe, D. A. & Kyba, M., Mar 2016, In : PloS one. 11, 3, e0151467.

Research output: Contribution to journalArticle

High-Frequency Hearing Loss
Audition
hearing
Transgenic Mice
Doxycycline
83 Citations (Scopus)

Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors

Lalit, P. A., Salick, M. R., Nelson, D. O., Squirrell, J. M., Shafer, C. M., Patel, N. G., Saeed, I., Schmuck, E. G., Markandeya, Y. S., Wong, R., Lea, M. R., Eliceiri, K. W., Hacker, T. A., Crone, W. C., Kyba, M., Garry, D. J., Stewart, R., Thomson, J. A., Downs, K. M., Lyons, G. E. & 1 others, Kamp, T. J., Mar 3 2016, In : Cell Stem Cell. 18, 3, p. 354-367 14 p.

Research output: Contribution to journalArticle

Stem Cells
Fibroblasts
Cardiac Myocytes
Smooth Muscle Myocytes
Endothelial Cells
1 Citation (Scopus)

Mesoderm, Cooked Up Fast and Served to Order

Kyba, M., Aug 4 2016, In : Cell Stem Cell. 19, 2, p. 146-148 3 p.

Research output: Contribution to journalShort survey

Mesoderm
Technology
59 Citations (Scopus)

MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome

Stavropoulou, V., Kaspar, S., Brault, L., Sanders, M. A., Juge, S., Morettini, S., Tzankov, A., Iacovino, M., Lau, I. J., Milne, T. A., Royo, H., Kyba, M., Valk, P. J. M., Peters, A. H. F. M. & Schwaller, J., Jul 11 2016, In : Cancer Cell. 30, 1, p. 43-58 16 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Hematopoietic Stem Cells
Acute Myeloid Leukemia
Leukemia
Genes
6 Citations (Scopus)

Transcriptional Inhibitors Identified in a 160,000-Compound Small-Molecule DUX4 Viability Screen

Choi, S. H., Bosnakovski, D., Strasser, J. M., Toso, E. A., Walters, M. A. & Kyba, M., Aug 1 2016, In : Journal of Biomolecular Screening. 21, 7, p. 680-688 9 p.

Research output: Contribution to journalArticle

Genes
Molecules
Oxidative stress
Oxidative Stress
Facioscapulohumeral Muscular Dystrophy
2015
35 Citations (Scopus)

Derivation and high engraftment of patient-specific cardiomyocyte sheet using induced pluripotent stem cells generated from adult cardiac fibroblast

Zhang, L., Guo, J., Zhang, P., Xiong, Q., Wu, S. C., Xia, L., Roy, S. S., Tolar, J., O'Connell, T. D., Kyba, M., Liao, K. & Zhang, J., Jan 1 2015, In : Circulation: Heart Failure. 8, 1, p. 156-166 11 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cardiac Myocytes
Fibroblasts
Transplantation
Wounds and Injuries
1 Citation (Scopus)

Drosophila Cyclin G and epigenetic maintenance of gene expression during development

Dupont, C. A., Dardalhon-Cuménal, D., Kyba, M., Brock, H. W., Randsholt, N. B. & Peronnet, F., May 7 2015, In : Epigenetics and Chromatin. 8, 1, 18.

Research output: Contribution to journalArticle

Cyclin G
Epigenomics
Drosophila
Maintenance
Homeobox Genes
19 Citations (Scopus)

Inducible Gata1 suppression expands megakaryocyteerythroid progenitors from embryonic stem cells

Noh, J. Y., Gandre-Babbe, S., Wang, Y., Hayes, V., Yao, Y., Gadue, P., Sullivan, S. K., Chou, S. T., Machlus, K. R., Italiano, J. E., Kyba, M., Finkelstein, D., Ulirsch, J. C., Sankaran, V. G., French, D. L., Poncz, M. & Weiss, M. J., Jun 1 2015, In : Journal of Clinical Investigation. 125, 6, p. 2369-2374 6 p.

Research output: Contribution to journalArticle

Megakaryocytes
Embryonic Stem Cells
Induced Pluripotent Stem Cells
Blood Platelets
Megakaryocyte-Erythroid Progenitor Cells
2014
74 Citations (Scopus)

Acquisition of a quantitative, stoichiometrically conserved ratiometric marker of maturation status in stem cell-derived cardiac myocytes

Bedada, F. B., Chan, S. S. K., Metzger, S. K., Zhang, L., Zhang, J., Garry, D. J., Kamp, T. J., Kyba, M. & Metzger, J. M., Oct 14 2014, In : Stem Cell Reports. 3, 4, p. 594-605 12 p.

Research output: Contribution to journalArticle

Stem cells
Cardiac Myocytes
Stem Cells
Induced Pluripotent Stem Cells
Protein Isoforms
32 Citations (Scopus)

Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages

Shi, X., Richard, J., Zirbes, K. M., Gong, W., Lin, G., Kyba, M., Thomson, J. A., Koyano-Nakagawa, N. & Garry, D. J., May 15 2014, In : Developmental Biology. 389, 2, p. 208-218 11 p.

Research output: Contribution to journalArticle

Endothelial Cells
Embryonic Development
Embryoid Bodies
Hematopoiesis
Proteins
77 Citations (Scopus)

Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators

Elcheva, I., Brok-Volchanskaya, V., Kumar, A., Liu, P., Lee, J. H., Tong, L., Vodyanik, M., Swanson, S., Stewart, R., Kyba, M., Yakubov, E., Cooke, J., Thomson, J. A. & Slukvin, I., Jul 14 2014, In : Nature communications. 5, 4372.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
stem cells
regulators
Stem cells
induction
40 Citations (Scopus)

Dominant Lethal Pathologies in Male Mice Engineered to Contain an X-Linked DUX4 Transgene

Dandapat, A., Bosnakovski, D., Hartweck, L. M., Arpke, R. W., Baltgalvis, K. A., Vang, D., Baik, J., Darabi, R., Perlingeiro, R. C. R., Hamra, F. K., Gupta, K., Lowe, D. A. & Kyba, M., Jan 1 2014, In : Cell reports. 8, 5, p. 1484-1496 13 p.

Research output: Contribution to journalArticle

Facioscapulohumeral Muscular Dystrophy
Doxycycline
Pathology
Transgenes
Retinal Vessels
Nucleic Acid Regulatory Sequences
Blood
DNA Methylation

Erratum: TBX3 directs cell-fate decision toward mesendoderm (Stem Cell Reports (2013) 1 (248-265))

Weidgang, C. E., Russell, R., Tata, P. R., Kühl, S. J., Illing, A., Müller, M., Lin, Q., Brunner, C., Boeckers, T. M., Bauer, K., Kartikasari, A. E. R., Guo, Y., Radenz, M., Bernemann, C., Weiß, M., Seufferlein, T., Zenke, M., Iacovino, M., Kyba, M., Schöler, H. R. & 3 others, Kühl, M., Liebau, S. & Kleger, A., May 6 2014, In : Stem Cell Reports. 2, 5, 1 p.

Research output: Contribution to journalComment/debate

Stem Cells
24 Citations (Scopus)

High-throughput screening identifies inhibitors of DUX4-induced myoblast toxicity

Bosnakovski, D., Choi, S. H., Strasser, J. M., Toso, E. A., Walters, M. A. & Kyba, M., Feb 1 2014, In : Skeletal Muscle. 4, 1, 4.

Research output: Contribution to journalArticle

Myoblasts
Facioscapulohumeral Muscular Dystrophy
Oxidative Stress
Chromosomes, Human, Pair 4
Proteins