Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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The pathogenic role of neuronal DNA-sensing cGAS–STING pathway in alpha-synucleinopathy
Poddar, I. (PI) & Lee, M. K. (CoI)
MICHAEL J. FOX FDN FOR PARKINSON'S RES.
4/1/26 → 3/31/28
Project: Research project
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Senescence in Parkinson's disease and related disorders
Lee, M. K. (PI), Niedernhofer, L. J. (PI) & Zhang, Y. (PI)
MICHAEL J. FOX FDN FOR PARKINSON'S RES.
4/8/25 → 4/7/27
Project: Research project
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Regulatory T Cells in Alzheimer's Disease
Farrar, M. A. (PI), Lee, M. K. (PI), Munro, S. A. (PI), Tracy, S. I. (PI), Zhang, Y. (PI) & Grzywacz, B. J. (Prior Principal Investigator)
NIH NATIONAL INSTITUTE ON AGING
8/16/22 → 5/31/27
Project: Research project
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Regulation of human tau expression and tauopathy by alpha-synuclein
Lee, M. K. (PI), Zhang, Y. (PI) & Lesne, S. E. (Prior Principal Investigator)
NIH NATIONAL INSTITUTE ON AGING
6/1/22 → 3/31/27
Project: Research project
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Targeting a novel adaptive stress response pathway for therapeutic intervention in alpha-synuclein-induced dementia
Lee, M. K. (PI)
MEDICAL UNIVERSITY OF SOUTH CAROLINA, U.S. DEPARTMENT OF DEFENSE
7/1/23 → 6/30/26
Project: Research project
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Internalized SNCA/α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade SNCA fibrils
Karim, M. R., Tiegs, E., Gasparini, E., Schlichte, R., Vermilyea, S. C. & Lee, M. K., 2026, In: Autophagy. 22, 1, p. 102-120 19 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Intranasal Delivery of Metabolically Resilient Glutathione: In Vivo Pharmacokinetic, Permeation, and Efficacy Studies
Bhilare, K. D., Dobariya, P., Lee, A., Xie, W., Xie, J., Meints, J., Vince, R., Lee, M. K. & More, S. S., Jul 7 2025, In: Molecular pharmaceutics. 22, 7, p. 4145-4157 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Scopus citations -
Oral Prodrug of a Novel Glutathione Surrogate Reverses Metabolic Dysregulation and Attenuates Neurodegenerative Process in Transgenic Alzheimer’s Mice
Rao, S. P., Imam-Fulani, A. O., Xie, W., Phillip, S., Chennavajula, K., Bhilare, K. D., Lind, E. B., Zhang, Y., Vince, R., Lee, M. K. & More, S. S., Aug 8 2025, In: ACS Pharmacology and Translational Science. 8, 8, p. 2448-2464 17 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Soluble and Insoluble Lysates from the Human A53T Mutant α-Synuclein Transgenic Mouse Model Induces α-Synucleinopathy Independent of Injection Site
Barnes, J., Vermilyea, S. C., Meints, J., Martell-Martinez, H. & Lee, M. K., Jul 2025, In: International journal of molecular sciences. 26, 13, 6254.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Tau pathology in the brainstem monoaminergic neurons reflect resilience to Alzheimer’s disease pathology in the Nun study cases
Pezhouh, M. K., Chen, G., Meints, J., Hemmy, L. S., SantaCruz, K. S. & Lee, M. K., Dec 2025, In: Acta Neuropathologica Communications. 13, 1, 239.Research output: Contribution to journal › Article › peer-review
Open Access