Michael K Lee

Professor, Neuroscience

Emailmklee@umn.edu

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Expertise related to UN SDGs

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

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7 Active
16 Finished

Senescence in Parkinson's disease and related disorders
Lee, M. K., Lesne, S. E. & Robbins, P. D.
MICHAEL J. FOX FDN FOR PARKINSON'S RES.
10/1/20 → 9/30/23
Project: Research project
Role of alpha-synuclein dependent network hyperexcitability in Lewy Body Dementia
Lee, M. K. & Lesne, S. E.
NIH NAT INST OF NEURO DISORDERS & STROKE
9/15/19 → 7/31/21
Project: Research project
Soluble aSyn is a modulator of AD pathophysiology
Lesne, S. E., Araque, A. & Lee, M. K.
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/19 → 3/31/24
Project: Research project
Role of glyoxalase-1 in Alzheimer's disease pathogenesis and therapy
More, S. S. & Lee, M. K.
NIH NAT'L INSTITUTE ON AGING (NIA)
8/15/19 → 4/30/24
Project: Research project
AMP-Kinase as a target for neuroprotection in AD
Lee, M. K., Lesne, S. E. & Liao, D.
NIH NAT'L INSTITUTE ON AGING (NIA)
2/15/19 → 1/31/24
Project: Research project

104 Article
5 Review article
3 Chapter
2 Comment/debate

Partial inhibition of mitochondrial complex I ameliorates Alzheimer’s disease pathology and cognition in APP/PS1 female mice
Stojakovic, A., Trushin, S., Sheu, A., Khalili, L., Chang, S. Y., Li, X., Christensen, T., Salisbury, J. L., Geroux, R. E., Gateno, B., Flannery, P. J., Dehankar, M., Funk, C. C., Wilkins, J., Stepanova, A., O’Hagan, T., Galkin, A., Nesbitt, J., Zhu, X., Tripathi, U. & 16 others, Macura, S., Tchkonia, T., Pirtskhalava, T., Kirkland, J. L., Kudgus, R. A., Schoon, R. A., Reid, J. M., Yamazaki, Y., Kanekiyo, T., Zhang, S., Nemutlu, E., Dzeja, P., Jaspersen, A., Kwon, Y. I. C., Lee, M. K. & Trushina, E., Jan 8 2021, In: Communications biology. 4, 1, 61.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
Ablating Tau Reduces Hyperexcitability and Moderates Electroencephalographic Slowing in Transgenic Mice Expressing A53T Human α-Synuclein
Peters, S. T., Fahrenkopf, A., Choquette, J. M., Vermilyea, S. C., Lee, M. K. & Vossel, K., Jun 19 2020, In: Frontiers in Neurology. 11, 563.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment
Karim, M. R., Liao, E. E., Kim, J., Meints, J., Martinez, H. M., Pletnikova, O., Troncoso, J. C. & Lee, M. K., Apr 16 2020, In: Molecular Neurodegeneration. 15, 1, 27.
Research output: Contribution to journal › Article › peer-review

Open Access
7 Scopus citations
Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson's disease
Stanojlovic, M., Pallais, J. P., Lee, M. K. & Kotz, C. M., Oct 30 2019, In: Molecular brain. 12, 1, 1 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy
Singh, B., Covelo, A., Martell-Martínez, H., Nanclares, C., Sherman, M. A., Okematti, E., Meints, J., Teravskis, P. J., Gallardo, C., Savonenko, A. V., Benneyworth, M. A., Lesne, S. E., Liao, D., Araque, A. & Lee, M. K., Oct 1 2019, In: Acta Neuropathologica. 138, 4, p. 551-574 24 p.
Research output: Contribution to journal › Article › peer-review

Open Access
18 Scopus citations