If you made any changes in Pure, your changes will be visible here soon.

Research Output 2009 2019

Filter
Article
2019

Stereoselective semi-synthesis of the neuroprotective natural product, serofendic acid

Perusse, D. & Smanski, M. J., Jan 1 2019, In : MedChemComm. 10, 6, p. 951-960 10 p.

Research output: Contribution to journalArticle

Biological Products
Equipment Reuse
Synthetic Biology
Ketones
Hydroxyl Radical
2018
Metabolic Engineering
Genes
Genetic Engineering
Workflow
Metabolic Networks and Pathways
2 Citations (Scopus)

Single Copy Transgene Integration in a Transcriptionally Active Site for Recombinant Protein Synthesis

O'Brien, S. A., Lee, K., Fu, H. Y., Lee, Z., Le, T. S., Stach, C., McCann, M. G., Zhang, A. Q., Smanski, M. J., Somia, N. V. & Hu, W-S., Oct 1 2018, In : Biotechnology Journal. 13, 10, 1800226.

Research output: Contribution to journalArticle

Transgenes
Recombinant Proteins
Catalytic Domain
Cell Line
Immunoglobulin G
2017
5 Citations (Scopus)

Engineering species-like barriers to sexual reproduction

Maselko, M., Heinsch, S. C., Chacon, J. M., Harcombe, W. & Smanski, M. J., Dec 1 2017, In : Nature communications. 8, 1, 883.

Research output: Contribution to journalArticle

Reproduction
Lethal Genes
engineering
directional control
Introduced Species
8 Citations (Scopus)

Genetic Design via Combinatorial Constraint Specification

Bhatia, S. P., Smanski, M. J., Voigt, C. A. & Densmore, D. M., Nov 17 2017, In : ACS Synthetic Biology. 6, 11, p. 2130-2135 6 p.

Research output: Contribution to journalArticle

Language
Specifications
Nitrogen Fixation
Nitrogen fixation
Formal languages

Genome sequences for Streptomyces spp. isolated from diseasesuppressive soils and long-term ecological research sites

Heinsch, S. C., Otto-Hanson, L., Hsu, S. Y., Kinkel, L. & Smanski, M. J., Jan 1 2017, In : Genome Announcements. 5, 23, e00493-17.

Research output: Contribution to journalArticle

Streptomyces
Soil
Genome
Research
Ecology
2016
12 Citations (Scopus)

Leveraging ecological theory to guide natural product discovery

Smanski, M. J., Schlatter, D. C. & Kinkel, L. L., Mar 1 2016, In : Journal of Industrial Microbiology and Biotechnology. 43, 2-3, p. 115-128 14 p.

Research output: Contribution to journalArticle

Biological Products
Biosynthesis
Ecology
Ecosystems
Genes
2014
150 Citations (Scopus)

Functional optimization of gene clusters by combinatorial design and assembly

Smanski, M. J., Bhatia, S., Zhao, D., Park, Y. J., Woodruff, L. B. A., Giannoukos, G., Ciulla, D., Busby, M., Calderon, J., Nicol, R., Gordon, D. B., Densmore, D. & Voigt, C. A., Dec 1 2014, In : Nature biotechnology. 32, 12, p. 1241-1249 9 p.

Research output: Contribution to journalArticle

Operon
Multigene Family
Genes
Microbial Genes
Klebsiella oxytoca
19 Citations (Scopus)

Mechanisms of self-resistance in the Platensimycin- and platencin-producing streptomyces platensis MA7327 and MA7339 strains

Peterson, R. M., Huang, T., Rudolf, J. D., Smanski, M. J. & Shen, B., Mar 20 2014, In : Chemistry and Biology. 21, 3, p. 389-397 9 p.

Research output: Contribution to journalArticle

Streptomyces
Fatty Acid Synthases
Biosynthesis
Fatty Acids
Genes
2013
11 Citations (Scopus)

Isolation and structural elucidation of glucoside congeners of platencin from Streptomyces platensis SB12600

Yu, Z., Rateb, M. E., Smanski, M. J., Peterson, R. M. & Shen, B., May 1 2013, In : Journal of Antibiotics. 66, 5, p. 291-294 4 p.

Research output: Contribution to journalArticle

Polycyclic Compounds
Aminophenols
Metabolic Engineering
Glucosides
Streptomyces
2012
28 Citations (Scopus)

Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners

Smanski, M. J., Casper, J., Peterson, R. M., Yu, Z., Rajski, S. R. & Shen, B., Dec 28 2012, In : Journal of Natural Products. 75, 12, p. 2158-2167 10 p.

Research output: Contribution to journalArticle

Multigene Family
Genes
Streptomyces
Streptomyces lividans
Biosynthesis
5 Citations (Scopus)
Diterpenes
Biosynthesis
Streptomyces
Biological Products
Ports and harbors
2011
67 Citations (Scopus)

Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis

Smanski, M. J., Yu, Z., Casper, J., Lin, S., Peterson, R. M., Chen, Y., Wendt-Pienkowski, E., Rajski, S. R. & Shen, B., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13498-13503 6 p.

Research output: Contribution to journalArticle

Kaurane Diterpenes
Biological Products
Type I Fatty Acid Synthase
Diterpenes
Streptomyces
2010
35 Citations (Scopus)

Engineering of streptomyces platensis MA7339 for overproduction of platencin and congeners

Yu, Z., Smanski, M. J., Peterson, R. M., Marchillo, K., Andes, D., Rajski, S. R. & Shen, B., Apr 16 2010, In : Organic Letters. 12, 8, p. 1744-1747 4 p.

Research output: Contribution to journalArticle

congeners
pathogens
antibiotics
regulators
Streptomyces
2009
59 Citations (Scopus)

Engineered streptomyces platensis strains that overproduce antibiotics platensimycin and platencin

Smanski, M. J., Peterson, R. M., Rajski, S. R. & Shen, B., Apr 1 2009, In : Antimicrobial agents and chemotherapy. 53, 4, p. 1299-1304 6 p.

Research output: Contribution to journalArticle

Streptomyces
Anti-Bacterial Agents
Gene Deletion
Biological Products
Clone Cells