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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Discovery and characterization of biocatalysts for ribosomally encoded alpha-N-methylated peptide natural products
NIH NIGMS NATL INST OF GENERAL
8/1/19 → 5/31/24
Project: Research project
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Diverse Protein Architectures and α- N-Methylation Patterns Define Split Borosin RiPP Biosynthetic Gene Clusters
Imani, A. S., Lee, A. R., Vishwanathan, N., De Waal, F. & Freeman, M. F., Apr 15 2022, In: ACS Chemical Biology. 17, 4, p. 908-917 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
TaxiBGC: a Taxonomy-Guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes
Gupta, V. K., Bakshi, U., Chang, D., Lee, A. R., Davis, J. M., Chandrasekaran, S., Jin, Y. S., Freeman, M. F. & Sung, J., Dec 2022, In: mSystems. 7, 6Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Conformational rearrangements enable iterative backbone N-methylation in RiPP biosynthesis
Miller, F. S., Crone, K. K., Jensen, M. R., Shaw, S., Harcombe, W. R., Elias, M. H. & Freeman, M. F., Dec 1 2021, In: Nature communications. 12, 1, 5355.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Enzyme-mediated backbone N-methylation in ribosomally encoded peptides
Matabaro, E., Song, H., Chepkirui, C., Kaspar, H., Witte, L., Naismith, J. H., Freeman, M. F. & Künzler, M., Jan 2021, Synthetic and Enzymatic Modifications of the Peptide Backbone. Petersson, E. J. (ed.). Academic Press Inc., p. 429-458 30 p. (Methods in Enzymology; vol. 656).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli
Rust, M., Helfrich, E. J. N., Freeman, M. F., Nanudorn, P., Field, C. M., Rückert, C., Kündig, T., Page, M. J., Webb, V. L., Kalinowski, J., Sunagawa, S. & Piel, J., Apr 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 17, p. 9508-9518 11 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations
Datasets
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Conformational rearrangements enable iterative backbone 𝑁-methylation in RiPP biosynthesis
Miller, F. S., Crone, K. K., Jensen, M. R., Shaw, S., Harcombe, W., Elias, M. H. & Freeman, M. F., Data Repository for the University of Minnesota, Jul 30 2021
DOI: 10.13020/y8ry-gm18, https://hdl.handle.net/11299/222603
Dataset