Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Full human gene replacement mouse models of Alzheimer's Disease
Koob, M. D. (PI), Rodney, A. (Graduate Student), Benzow, K. A. (Other Role), Karanjeet, K. B. (Other Role), Leon, M. (Other Role) & Schnapp, B. (Other Role)
NIH NATIONAL INSTITUTE ON AGING
9/1/25 → 8/31/27
Project: Research project
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Single-cell transcriptomic and epigenomic analysis of brain cell vulnerabilities to tauopathies in early AD impacted brain regions
Koob, M. D. (PI) & Ebner, T. J. (CoI)
UNIVERSITY OF CALIFORNIA, IRVINE, NATIONAL INSTITUTES OF HEALTH (NIH)
6/1/23 → 2/28/26
Project: Research project
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Targeting axonal injuries and tau mislocalization to treat TBI and secondary injuries
Liao, D. (PI), Alford, P. W. (CoI) & Koob, M. D. (CoI)
THE HENRY M. JACKSON FOUNDATION, U.S. DEPARTMENT OF DEFENSE
3/6/23 → 3/5/27
Project: Research project
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Full human gene replacement mouse models of Alzheimer's Disease
Koob, M. D. (PI)
NIH NATIONAL INSTITUTE ON AGING
9/1/22 → 8/31/25
Project: Research project
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Matched sets of full human gene-replacement mouse lines for MODEL-AD
Koob, M. D. (PI)
NIH NATIONAL INSTITUTE ON AGING
9/1/21 → 8/31/22
Project: Research project
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A common Alu insertion in the 3'UTR of TMEM106B is associated with risk of dementia
Rodney, A., Karanjeet, K., Benzow, K. & Koob, M. D., Jul 2024, In: Alzheimer's and Dementia. 20, 7, p. 5071-5077 7 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Correction to: The Transcription Factor, α1ACT, Acts Through a MicroRNA Network to Regulate Neurogenesis and Cell Death During Neonatal Cerebellar Development (The Cerebellum, (2022), 22, 4, (651-662), 10.1007/s12311-022-01431-2)
Wei, C., Benzow, K., Koob, M. D., Gomez, C. M. & Du, X., Apr 2024, In: Cerebellum. 23, 2, p. 876 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice
Benzow, K., Karanjeet, K., Oblak, A. L., Carter, G. W., Sasner, M. & Koob, M. D., Apr 2024, In: Alzheimer's and Dementia. 20, 4, p. 3080-3087 8 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Human ACE2 Gene Replacement Mice Support SARS-CoV-2 Viral Replication and Nonlethal Disease Progression
Thiede, J. M., Dick, J. K., Jarjour, N. N., Krishna, V. D., Qian, L., Sangala, J., Benzow, K., Karanjeet, K., Chin, S., Rainwater, O., Cheeran, M. C. J., Hogquist, K. A., Jameson, S. C., Hart, G. T., Bold, T. D. & Koob, M. D., Sep 1 2024, In: ImmunoHorizons. 8, 9, p. 712-720 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease
Duvick, L., Southern, W. M., Benzow, K. A., Burch, Z. N., Handler, H. P., Mitchell, J. S., Kuivinen, H., Gadiparthi, U., Yang, P., Soles, A., Sheeler, C. A., Rainwater, O., Serres, S., Lind, E. B., Nichols-Meade, T., You, Y., O'Callaghan, B., Zoghbi, H. Y., Cvetanovic, M. & Wheeler, V. C. & 3 others, , May 8 2024, In: JCI Insight. 9, 9, e176057.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations