Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Mechanisms and Therapy of Chronic Graft-vs.-Host Disease; Project 2: Metabolomics of cGVHD
Blazar, B. R. (PI), Hartigan, C. (Other Role), Saha, A. (Other Role) & Zaiken, M. C. (Other Role)
DANA-FARBER CANCER INSTITUTE, NIH NATL HEART, LUNG AND BLOOD INSTITU
9/15/22 → 8/31/26
Project: Research project
Research output
- 16 Article
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Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion
McDonald-Hyman, C., Aguilar, E. G., Compeer, E. B., Zaiken, M. C., Rhee, S. Y., Mohamed, F. A., Larson, J. H., Loschi, M. L., Lees, C., Thangavelu, G., Sleeth, M. L., Smith, K. D., Whangbo, J. S., Ritz, J., Sparwasser, T. D., O’Connor, R. S., Crawford, P. A., Rathmell, J. C., Kean, L. S. & Zeiser, R. & 3 others, , 2026, In: Journal of Clinical Investigation. 136, 1, p. 1-21 21 p., e182480.Research output: Contribution to journal › Article › peer-review
Open Access -
Acetyl-CoA carboxylase 1 inhibition increases Treg metabolism and graft-versus-host disease treatment efficacy via mitochondrial fusion
McDonald-Hyman, C., Aguilar, E. G., Compeer, E. B., Zaiken, M. C., Rhee, S. Y., Mohamed, F. A., Larson, J. H., Loschi, M. L., Lees, C., Thangavelu, G., Sleeth, M. L., Smith, K. D., Whangbo, J. S., Ritz, J., Sparwasser, T. D., O’Connor, R. S., Crawford, P. A., Rathmell, J. C., Kean, L. S. & Zeiser, R. & 3 others, , Dec 2025, In: Journal of Clinical Investigation. 135, 23, e182480.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Deficiency of T follicular helper cell Tet3 DNA demethylation inhibits pathogenic IgG2c class switching and chronic GVHD
Zaiken, M. C., Jin, S., McDonald-Hyman, C. S., Hartigan, C. R., Sage, P. T., Hippen, K. L., Koehn, B. H., Panoskaltsis-Mortari, A., Riddle, M. J., Eide, C. R., Tolar, J., Hill, G. R., Luznik, L., Cutler, C. S., Ritz, J. R., Kean, L. S., Tsagaratou, A., Rao, A. & Blazar, B. R., Jun 12 2025, In: Blood. 145, 24, p. 2813-2827 15 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Scopus citations -
Inflammasome-resistant IPSC-derived myeloid-derived suppressor cells ameliorate xenogeneic graft-versus-host disease
Ma, L., Koehn, B., Zaiken, M., Hippen, K. L., Smith, K., Allred, J., Williams, R., Yao, K., Fink, J., Saha, A., Koop, B., Payne, N., Widelak, R., Panoskaltsis-Mortari, A., Riddle, M. J., Tolar, J., Eide, C., Xia, L., Witty, A. D. & Mehta, A. K. & 9 others, , Oct 23 2025, In: Blood. 146, 17, p. 2047-2062 16 p.Research output: Contribution to journal › Article › peer-review
3 Link opens in a new tab Scopus citations -
Targeting cell-surface VISTA expression on allospecific naïve T cells promotes tolerance
Koehn, B. H., Nowak, E. C., Skopelja-Gardner, S., Saha, A., Zaiken, M. C., Allred, J., Peng, Y., Davis, W. L., Le Mercier, I., Schwertner, N., Molloy, M. J., Rothstein, J., Carriere, C., Riddle, M. J., Eide, C. R., Tolar, J., Panoskaltsis-Mortari, A., Smith, K. D., Hippen, K. L. & Kim, T. K. & 2 others, , Apr 10 2025, In: Blood. 145, 15, p. 1687-1700 14 p.Research output: Contribution to journal › Article › peer-review
4 Link opens in a new tab Scopus citations