1983 …2019

Research output per year

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1983

A new insertion sequence, IS121, is found on the Mu dI1(Ap lac) bacteriophage and the Escherichia coli K-12 chromosome

O'Connor, M. B. & Malamy, M. H., Dec 1 1983, In : Journal of bacteriology. 156, 2, p. 669-679 11 p.

Research output: Contribution to journalArticle

15 Scopus citations
1984
14 Scopus citations

Site-specific recombination in the oriV1 region of the F factor.

O'Connor, M. B. & Malamy, M. H., 1984, In : Cold Spring Harbor symposia on quantitative biology. 49, p. 421-434 14 p.

Research output: Contribution to journalArticle

3 Scopus citations
1985

A frameshift mutation at the junction of an IS1 insertion within lacZ restores β-galactosidase activity via formation of an active lacZ-IS1 fusion protein

Malamy, M. H., Rahaim, P. T., Hoffman, C. S., Baghdoyan, D., O'Connor, M. B. & Miller, J. F., Feb 20 1985, In : Journal of Molecular Biology. 181, 4, p. 551-555 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Mapping of DNA gyrase cleavage sites in vivo oxolinic acid induced cleavages in plasmid pBR322

O'Connor, M. B. & Malamy, M. H., Feb 20 1985, In : Journal of Molecular Biology. 181, 4, p. 545-550 6 p.

Research output: Contribution to journalArticle

28 Scopus citations
1986

Site-specific and illegitimate recombination in the oriV1 region of the F factor. DNA sequences involved in recombination and resolution

O'Connor, M. B., Kilbane, J. J. & Malamy, M. H., May 5 1986, In : Journal of Molecular Biology. 189, 1, p. 85-102 18 p.

Research output: Contribution to journalArticle

14 Scopus citations
1988

Alternative RNA products from the Ultrabithorax domain of the bithorax complex.

O'Connor, M. B., Binari, R., Perkins, L. A. & Bender, W., Feb 1988, In : The EMBO journal. 7, 2, p. 435-445 11 p.

Research output: Contribution to journalArticle

77 Scopus citations
1989

Construction of large DNA segments in Escherichia coli

O'Connor, M., Peifer, M. & Bender, W., Jan 1 1989, In : Science. 244, 4910, p. 1307-1312 6 p.

Research output: Contribution to journalArticle

147 Scopus citations
1990

Regulatory elements of the bithorax complex that control expression along the anterior-posterior axis

Simon, J., Peifer, M., Bender, W. & O'Connor, M., Nov 29 1990, In : EMBO Journal. 9, 12, p. 3945-3956 12 p.

Research output: Contribution to journalArticle

108 Scopus citations
1991

The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1

Shimell, M. J., Ferguson, E. L., Childs, S. R. & O'Connor, M. B., Nov 1 1991, In : Cell. 67, 3, p. 469-481 13 p.

Research output: Contribution to journalArticle

245 Scopus citations
1993

Elements of the Drosophila bithorax complex that mediate repression by polycomb group products

Simon, J., Chiang, A., Bender, W., Shimell, M. J. & O’connor, M., Jul 1993, In : Developmental Biology. 158, 1, p. 131-144 14 p.

Research output: Contribution to journalArticle

225 Scopus citations

Identification of a Drosophila activin receptor

Childs, S. R., Wrana, J. L., Arora, K., Attisano, L., O'Connor, M. B. & Massagué, J., Oct 15 1993, In : Proceedings of the National Academy of Sciences of the United States of America. 90, 20, p. 9475-9479 5 p.

Research output: Contribution to journalArticle

91 Scopus citations
1994

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

Brummel, T. J., Twombly, V., Marqués, G., Wrana, J. L., Newfeld, S. J., Attisano, L., Massagué, J., O'Connor, M. B. & Gelbart, W. M., Jul 29 1994, In : Cell. 78, 2, p. 251-261 11 p.

Research output: Contribution to journalArticle

250 Scopus citations

Characterization of tolloid-related-1: A BMP-1-like productthat is required during larval and pupal stages of drosophila development

Nguyen, T., Jamal, J., Shimell, M. J., Arora, K. & O’Connor, M. B., Dec 1994, In : Developmental Biology. 166, 2, p. 569-586 18 p.

Research output: Contribution to journalArticle

65 Scopus citations

Enhancer point mutation results in a homeotic transformation in drosophila

Shimell, M. J., Simon, J., Bender, W. & O'Connor, M. B., Jan 1 1994, In : Science. 264, 5161, p. 968-971 4 p.

Research output: Contribution to journalArticle

69 Scopus citations

Enhancer traps in the Drosophila bithorax complex mark parasegmental domains

McCall, K., O'Connor, M. B. & Bender, W., Jan 1 1994, In : Genetics. 138, 2, p. 387-399 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

The Drosophila dorsal morphogen represses the tolloid gene by interacting with a silencer element

Kirov, N., Childs, S., O'Connor, M. & Rushlow, C., Jan 1 1994, In : Molecular and cellular biology. 14, 1, p. 713-722 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

The screw gene encodes a ubiquitously expressed member of the TGF-β family required for specification of dorsal cell fates in the Drosophila embryo

Arora, K., Levine, M. S. & O'Connor, M. B., Nov 1 1994, In : Genes and Development. 8, 21, p. 2588-2601 14 p.

Research output: Contribution to journalArticle

169 Scopus citations

Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex

Wrana, J. L., Tran, H., Attisano, L., Arora, K., Childs, S. R., Massagué, J. & O'Connor, M. B., Feb 1994, In : Molecular and cellular biology. 14, 2, p. 944-950 7 p.

Research output: Contribution to journalArticle

130 Scopus citations

Two domains of the tolloid protein contribute to its unusual genetic interaction with decapentaplegic

Childs, S. R. & O’connor, M. B., Mar 1994, In : Developmental Biology. 162, 1, p. 209-220 12 p.

Research output: Contribution to journalArticle

60 Scopus citations
1995

Discrete Polycomb-binding sites in each parasegmental domain of the bithorax complex

Chiang, A., O'Connor, M. B., Paro, R., Simon, J. & Bender, W., Jan 1 1995, In : Development. 121, 6, p. 1681-1689 9 p.

Research output: Contribution to journalArticle

100 Scopus citations

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

Letsou, A., Arora, K., Wrana, J. L., Simin, K., Twombly, V., Jamal, J., Staehling-Hampton, K., Hoffmann, F. M., Gelbart, W. M., Massagué, J. & O'Connor, M. B., Mar 24 1995, In : Cell. 80, 6, p. 899-908 10 p.

Research output: Contribution to journalArticle

225 Scopus citations

Functional reconstruction of trans regulation of the Ultrabithorax promoter by the products of two antagonistic genes, trithorax and Polycomb

Chang, Y. L., King, B. O., O'Connor, M., Mazo, A. & Huang, D. H., Dec 1995, In : Molecular and cellular biology. 15, 12, p. 6601-6612 12 p.

Research output: Contribution to journalArticle

42 Scopus citations

The drosophila schnurri gene acts in the Dpp/TGFβ signaling pathway and encodes a transcription factor homologous to the human MBP family

Arora, K., Dai, H., Kazuko, S. G., Jamal, J., O'Connor, M. B., Letsou, A. & Warrior, R., Jun 2 1995, In : Cell. 81, 5, p. 781-790 10 p.

Research output: Contribution to journalArticle

188 Scopus citations
1996

BMP signaling in Drosophila embryogenesis

Arora, K., O'Connor, M. B. & Warrior, R., Jan 1 1996, In : Annals of the New York Academy of Sciences. 785, p. 80-97 18 p.

Research output: Contribution to journalArticle

7 Scopus citations

Developmental territories created by mutual antagonism between wingless and decapentaplegic

Theisen, H., Haerry, T. E., O'Connor, M. B. & Lawrence Marsh, J., Dec 1 1996, In : Development. 122, 12, p. 3939-3948 10 p.

Research output: Contribution to journalArticle

114 Scopus citations

MADR1, a MAD-related protein that functions in BMP2 signaling pathways

Hoodless, P. A., Haerry, T., Abdollah, S., Stapleton, M., O'Connor, M. B., Attisano, L. & Wrana, J. L., May 1996, In : Cell. 85, 4, p. 489-500 12 p.

Research output: Contribution to journalArticle

606 Scopus citations

The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor

Holley, S. A., Neul, J. L., Attisano, L., Wrana, J. L., Sasai, Y., O'Connor, M. B., De Robertis, E. M. & Ferguson, E. L., Aug 23 1996, In : Cell. 86, 4, p. 607-617 11 p.

Research output: Contribution to journalArticle

188 Scopus citations
1997

Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila

Haerry, T. E., Heslip, T. R., Marsh, J. L. & O'Connor, M. B., Sep 25 1997, In : Development. 124, 16, p. 3055-3064 10 p.

Research output: Contribution to journalArticle

174 Scopus citations

Production of a DPP activity gradient in the early drosophila embryo through the opposing actions of the SOG and TLD proteins

Marqués, G., Musacchio, M., Shimell, M. J., Wünnenberg-Stapleton, K., Cho, K. W. Y. & O'Connor, M. B., Oct 31 1997, In : Cell. 91, 3, p. 417-426 10 p.

Research output: Contribution to journalArticle

291 Scopus citations
1998

Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila

Haerry, T. E., Khalsa, O., O'Connor, M. B. & Wharton, K. A., Nov 23 1998, In : Development. 125, 20, p. 3977-3987 11 p.

Research output: Contribution to journalArticle

178 Scopus citations
1999

The Drosophila activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development

Brummel, T., Abdollah, S., Haerry, T. E., Shimell, M. J., Merriam, J., Raftery, L., Wrana, J. L. & O'Connor, M. B., Jan 1 1999, In : Genes and Development. 13, 1, p. 98-111 14 p.

Research output: Contribution to journalArticle

147 Scopus citations
2000

Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene

Shimell, M. J., Peterson, A. J., Burr, J., Simon, J. A. & O'Connor, M. B., Feb 1 2000, In : Developmental Biology. 218, 1, p. 38-52 15 p.

Research output: Contribution to journalArticle

70 Scopus citations

Is chordin a long-range- or short-range-acting factor? Roles for BMP1- related metalloproteases in chordin and BMP4 autofeedback loop regulation

Blitz, I. L., Shimmi, O., Wünnenberg-Stapleton, K., O'Connor, M. B. & Cho, K. W. Y., Jul 1 2000, In : Developmental Biology. 223, 1, p. 120-138 19 p.

Research output: Contribution to journalArticle

53 Scopus citations

Processing of the Drosophila Sog protein creates a novel BMP inhibitory activity

Yu, K., Srinivasan, S., Shimmi, O., Biehs, B., Rashka, K. E., Kimelman, D., O'Connor, M. B. & Bier, E., May 1 2000, In : Development. 127, 10, p. 2143-2154 12 p.

Research output: Contribution to journalArticle

86 Scopus citations

TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development

Takatsu, Y., Nakamura, M., Stapleton, M., Danos, M. C., Matsumoto, K., O'Connor, M. B., Shibuya, H. & Ueno, N., May 1 2000, In : Molecular and cellular biology. 20, 9, p. 3015-3026 12 p.

Research output: Contribution to journalArticle

103 Scopus citations

The Drosophila disembodied gene controls late embryonic morphogenesis and codes for a cytochrome P450 enzyme that regulates embryonic ecdysone levels

Chavez, V. M., Marques, G., Delbecque, J. P., Kobayashi, K., Hollingsworth, M., Burr, J., Natzle, J. E. & O'Connor, M. B., Nov 23 2000, In : Development. 127, 19, p. 4115-4126 12 p.

Research output: Contribution to journalArticle

206 Scopus citations
2001

Twisted is a conserved extracellular BMP antagonist

Ross, J. J., Shimmi, O., Vilmos, P., Petryk, A., Kim, H., Gaudenz, K., Hermanson, S., Ekker, S. C., O'connor, M. B. & Marsh, J. L., Mar 22 2001, In : Nature. 410, 6827, p. 479-483 5 p.

Research output: Contribution to journalArticle

227 Scopus citations
2002

Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

Müller, J., Hart, C. M., Francis, N. J., Vargas, M. L., Sengupta, A., Wild, B., Miller, E. L., O'Connor, M. B., Kingston, R. E. & Simon, J. A., Oct 18 2002, In : Cell. 111, 2, p. 197-208 12 p.

Research output: Contribution to journalArticle

1079 Scopus citations

Isolation of Drosophila activin and follistatin cDNAs using novel MACH amplification protocols

Haerry, T. E. & O'Connor, M. B., May 29 2002, In : Gene. 291, 1-2, p. 85-93 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Molecular and biochemical characterization of two P450 enzymes in the ecdysteroidogenic pathway of Drosophila melanogaster

Warren, J. T., Petryk, A., Marqués, G., Jarcho, M., Parvy, J. P., Dauphin-Villemant, C., O'Connor, M. B. & Gilbert, L. I., Aug 20 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 17, p. 11043-11048 6 p.

Research output: Contribution to journalArticle

222 Scopus citations

Morphogenetic apoptosis: A mechanism for correcting discontinuities in morphogen gradients

Adachi-Yamada, T. & O'Connor, M. B., Jan 1 2002, In : Developmental Biology. 251, 1, p. 74-90 17 p.

Research output: Contribution to journalArticle

109 Scopus citations

The Drosophila BMP type II receptor wishful thinking regulates neuromuscular synapse morphology and function

Marqués, G., Bao, H., Haerry, T. E., Shimell, M. J., Duchek, P., Zhang, B. & O'Connor, M. B., Feb 14 2002, In : Neuron. 33, 4, p. 529-543 15 p.

Research output: Contribution to journalArticle

239 Scopus citations
2003

Expression of TAK1, a mediator of TGF-β and BMP signaling, during mouse embryonic development

Jadrich, J. L., O'Connor, M. B. & Coucouvanis, E., May 1 2003, In : Gene Expression Patterns. 3, 2, p. 131-134 4 p.

Research output: Contribution to journalArticle

26 Scopus citations
83 Scopus citations

Retrograde Gbb signaling through the Bmp type 2 receptor wishful thinking regulates systemic FMRFa expression in Drosophila

Marques, G., Haerry, T. E., Crotty, M. L., Xue, M., Zhang, B. & O'Connor, M. B., Nov 1 2003, In : Development. 130, 22, p. 5457-5470 14 p.

Research output: Contribution to journalArticle

78 Scopus citations

Shade is the Drosophila P450 enzyme that mediates the hydroxylation of ecdysone to the steroid insect molting hormone 20-hydroxyecdysone

Petryk, A., Warren, J. T., Marqués, G., Jarcho, M. P., Gilbert, L. I., Kahler, J., Parvy, J. P., Li, Y., Dauphin-Villemant, C. & O'Connor, M. B., Nov 25 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, SUPPL. 2, p. 13773-13778 6 p.

Research output: Contribution to journalArticle

258 Scopus citations

TGF-β signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain

Zheng, X., Wang, J., Haerry, T. E., Wu, A. Y. H., Martin, J., O'Connor, M. B., Lee, C. H. J. & Lee, T., Feb 7 2003, In : Cell. 112, 3, p. 303-315 13 p.

Research output: Contribution to journalArticle

170 Scopus citations

The BMP homolog Gbb provides a retrograde signal that regulates synaptic growth at the Drosophila neuromuscular junction

McCabe, B. D., Marqués, G., Haghighi, A. P., Fetter, R. D., Crotty, M. L., Haerry, T. E., Goodman, C. S. & O'Connor, M. B., Jul 17 2003, In : Neuron. 39, 2, p. 241-254 14 p.

Research output: Contribution to journalArticle

288 Scopus citations
2004

Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance

Johnson, K. G., Ghose, A., Epstein, E., Lincecum, J., O'Connor, M. B. & Van Vactor, D., Mar 23 2004, In : Current Biology. 14, 6, p. 499-504 6 p.

Research output: Contribution to journalArticle

157 Scopus citations