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  • 21 Similar Profiles
Regulatory T-Lymphocytes Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
B-Lymphoid Precursor Cells Medicine & Life Sciences
STAT5 Transcription Factor Medicine & Life Sciences
Interleukin-7 Medicine & Life Sciences
Interleukin-2 Medicine & Life Sciences
Precursor Cell Lymphoblastic Leukemia-Lymphoma Medicine & Life Sciences

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Projects 1996 2022

PD1 inhibition in BCR-ABL+ B-ALL

Farrar, M. A.

Merck

11/1/1610/31/18

Project: Research project

immunosuppression
lymphocytic leukemia
transposons
genes
Immune Tolerance
Tumor Necrosis Factor Receptors

Research Output 1989 2018

Identification of cellular sources of IL-2 needed for regulatory T cell development and homeostasis

Owen, D. L., Mahmud, S. A., Vang, K. B., Kelly, R. M., Blazar, B. R., Smith, K. A. & Farrar, M. A., Jun 15 2018, In : Journal of Immunology. 200, 12, p. 3926-3933 8 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Interleukin-2
Homeostasis
Dendritic Cells
Interleukin-15
5 Citations

Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival

Katerndahl, C. D. S., Heltemes-Harris, L. M., Willette, M. J. L., Henzler, C. M., Frietze, S., Yang, R., Schjerven, H., Silverstein, K. A. T., Ramsey, L. B., Hubbard, G., Wells, A. D., Kuiper, R. P., Scheijen, B., van Leeuwen, F. N., Müschen, M., Kornblau, S. M. & Farrar, M. A., May 18 2017, In : Nature Immunology. 18, 6, p. 694-704 11 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
B-Lymphocytes
STAT5 Transcription Factor
Survival

Combination therapeutics of Nilotinib and radiation in acute lymphoblastic leukemia as an effective method against drug-resistance

Kaveh, K., Takahashi, Y., Farrar, M. A., Storme, G., Guido, M., Piepenburg, J., Penning, J., Foo, J., Leder, K. Z. & Hui, S. K., Jul 1 2017, In : PLoS Computational Biology. 13, 7, e1005482

Research output: Contribution to journalArticle

drug resistance
Drug Resistance
lymphocytic leukemia
Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
3 Citations

STAT5 and CD4+ T Cell Immunity

Farrar, M. A. & Owen, D. L., Jan 1 2017, In : F1000Research. 6, 32

Research output: Contribution to journalReview article

T-cells
T-Lymphocyte Subsets
Regulatory T-Lymphocytes
Helper-Inducer T-Lymphocytes
Thymus Gland
2 Citations

STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development

Brady, N. J., Farrar, M. A. & Schwertfeger, K. L., Aug 1 2017, In : Developmental Biology. 428, 1, p. 232-244 13 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Macrophages
Aromatase
Morphogenesis
Estrogen Receptors