20042023

Research output per year

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Research Output

2020

Non-enzymatic Activity of the α-Tubulin Acetyltransferase αTAT Limits Synaptic Bouton Growth in Neurons

Coombes, C. E., Saunders, H. A. J., Mannava, A. G., Johnson-Schlitz, D. M., Reid, T. A., Parmar, S., McClellan, M., Yan, C., Rogers, S. L., Parrish, J. Z., Wagenbach, M., Wordeman, L., Wildonger, J. & Gardner, M. K., Feb 24 2020, In : Current Biology. 30, 4, p. 610-623.e5

Research output: Contribution to journalArticle

2019

A Gradient in Metaphase Tension Leads to a Scaled Cellular Response in Mitosis

Mukherjee, S., Sandri, B. J., Tank, D., McClellan, M., Harasymiw, L. A., Yang, Q., Parker, L. L. & Gardner, M. K., Apr 8 2019, In : Developmental Cell. 49, 1, p. 63-76.e10

Research output: Contribution to journalArticle

2 Scopus citations

Centromere mechanical maturation during mammalian cell mitosis

Harasymiw, L. A., Tank, D., McClellan, M., Panigrahy, N. & Gardner, M. K., Dec 1 2019, In : Nature communications. 10, 1, 1761.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Structural state recognition facilitates tip tracking of eb1 at growing microtubule ends

Reid, T. A., Coombes, C., Mukherjee, S., Goldblum, R. R., White, K., Parmar, S., McClellan, M., Zanic, M., Courtemanche, N. & Gardner, M. K., Sep 2019, In : eLife. 8, e48117.

Research output: Contribution to journalArticle

Open Access

UNC-45A is a novel microtubule-associated protein and regulator of paclitaxel sensitivity in ovarian cancer cells

Mooneyham, A., Iizuka, Y., Yang, Q., Coombes, C., McClellan, M., Shridhar, V., Emmings, E., Shetty, M., Chen, L., Ai, T., Meints, J., Lee, M. K., Gardner, M. K. & Bazzaro, M., Feb 2019, In : Molecular Cancer Research. 17, 2, p. 370-383 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2017

Manipulation and quantification of microtubule lattice integrity

Reid, T. A., Coombes, C. & Gardner, M. K., Aug 15 2017, In : Biology Open. 6, 8, p. 1245-1256 12 p.

Research output: Contribution to journalArticle

3 Scopus citations
2016

A noncatalytic function of the topoisomerase II CTD in Aurora B recruitment to inner centromeres during mitosis

Edgerton, H., Johansson, M., Keifenheim, D., Mukherjee, S., Chacón, J. M., Bachant, J., Gardner, M. K. & Clarke, D. J., Jan 1 2016, In : Journal of Cell Biology. 213, 6, p. 651-664 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

A novel role for SALL4 during scar-free wound healing in axolotl

Erickson, J. R., Gearhart, M. D., Honson, D. D., Reid, T. A., Gardner, M. K., Moriarity, B. S. & Echeverri, K., Dec 1 2016, In : Regenerative Medicine. 1, 1

Research output: Contribution to journalArticle

Open Access

Cell Biology: Microtubule Collisions to the Rescue

Gardner, M. K., Dec 19 2016, In : Current Biology. 26, 24, p. R1287-R1289

Research output: Contribution to journalShort survey

Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex in Drosophila

Mauvezin, C., Neisch, A. L., Ayala, C. I., Kim, J., Beltrame, A., Braden, C. R., Gardner, M. K., Hays, T. S. & Neufeld, T. P., Jan 1 2016, In : Journal of cell science. 129, 5, p. 971-982 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Geometry and expression enhance enrichment of functional yeast-displayed ligands via cell panning

Stern, L. A., Schrack, I. A., Johnson, S. M., Deshpande, A., Bennett, N. R., Harasymiw, L. A., Gardner, M. K. & Hackel, B. J., Nov 1 2016, In : Biotechnology and bioengineering. 113, 11, p. 2328-2341 14 p.

Research output: Contribution to journalArticle

13 Scopus citations

Interactions between the Microtubule Binding Protein EB1 and F-Actin

Alberico, E. O., Zhu, Z. C., Wu, Y. F. O., Gardner, M. K., Kovar, D. R. & Goodson, H. V., Mar 27 2016, In : Journal of Molecular Biology. 428, 6, p. 1304-1314 11 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Mechanism of microtubule lumen entry for the α-tubulin acetyltransferase enzyme αTAT1

Coombes, C., Yamamoto, A., McClellan, M., Reid, T. A., Plooster, M., Luxton, G. W. G., Alper, J., Howard, J. & Gardner, M. K., Nov 15 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 46, p. E7176-E7184

Research output: Contribution to journalArticle

25 Scopus citations

Suppression of microtubule assembly kinetics by the mitotic protein TPX2

Reid, T. A., Schuster, B. M., Mann, B. J., Balchand, S. K., Plooster, M., McClellan, M., Coombes, C. E., Wadsworth, P. & Gardner, M. K., Apr 1 2016, In : Journal of cell science. 129, 7, p. 1319-1328 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Microtubule binding distinguishes dystrophin from utrophin

Belanto, J. J., Mader, T. L., Eckhoff, M. D., Strandjord, D. M., Banks, G. B., Gardner, M. K., Lowe, D. A. & Ervasti, J. M., Apr 15 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 15, p. 5723-5728 6 p.

Research output: Contribution to journalArticle

58 Scopus citations

Minus-end-directed kinesin-14 motors align antiparallel microtubules to control metaphase spindle length

Hepperla, A. J., Willey, P. T., Coombes, C. E., Schuster, B. M., Gerami-Nejad, M., McClellan, M., Mukherjee, S., Fox, J., Winey, M., Odde, D. J., O'Toole, E. & Gardner, M. K., Oct 13 2014, In : Developmental Cell. 31, 1, p. 61-72 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Pericentromere tension is self-regulated by spindle structure in metaphase

Chacón, J. M., Mukherjee, S., Schuster, B. M., Clarke, D. J. & Gardner, M. K., 2014, In : Journal of Cell Biology. 205, 3, p. 313-324 12 p.

Research output: Contribution to journalArticle

23 Scopus citations

Quantitative analysis of microtubule self-assembly kinetics and tip structure

Prahl, L. S., Castle, B. T., Gardner, M. K. & Odde, D. J., Jan 1 2014, Reconstituting the Cytoskeleton. Academic Press Inc., p. 35-52 18 p. (Methods in Enzymology; vol. 540).

Research output: Chapter in Book/Report/Conference proceedingChapter

19 Scopus citations

Rapid microtubule self-assembly kinetics

Gardner, M. K., Charlebois, B. D., Jánosi, I. M., Howard, J., Hunt, A. J. & Odde, D. J., Sep 25 2014, In : Cell. 159, 1, 1 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
2013
5 Scopus citations

CENP-E hangs on at dynamic microtubule ends

Gardner, M. K., Sep 1 2013, In : Nature Cell Biology. 15, 9, p. 1030-1032 3 p.

Research output: Contribution to journalReview article

Evolving tip structures can explain age-dependent microtubule catastrophe

Coombes, C. E., Yamamoto, A., Kenzie, M. R., Odde, D. J. & Gardner, M. K., Jul 22 2013, In : Current Biology. 23, 14, p. 1342-1348 7 p.

Research output: Contribution to journalArticle

57 Scopus citations

Genome-wide haploinsufficiency screen reveals a novel role for γ-TuSC in spindle organization and genome stability

Choy, J. S., O'Toole, E., Schuster, B. M., Crisp, M. J., Karpova, T. S., McNally, J. G., Winey, M., Gardner, M. K. & Basrai, M. A., Sep 1 2013, In : Molecular biology of the cell. 24, 17, p. 2753-2763 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Microtubule catastrophe and rescue.

Gardner, M. K., Zanic, M. & Howard, J., Feb 2013, In : Current Opinion in Cell Biology. 25, 1, p. 14-22 9 p.

Research output: Contribution to journalArticle

81 Scopus citations

Monopolin recruits condensin to organize centromere DNA and repetitive DNA sequences

Burrack, L. S., Applen Clancey, S. E., Chacón, J. M., Gardner, M. K. & Berman, J., Sep 15 2013, In : Molecular biology of the cell. 24, 18, p. 2807-2819 13 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Dynein tethers and stabilizes dynamic microtubule plus ends

Hendricks, A. G., Lazarus, J. E., Perlson, E., Gardner, M. K., Odde, D. J., Goldman, Y. E. & Holzbaur, E. L. F., Apr 10 2012, In : Current Biology. 22, 7, p. 632-637 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Islands containing slowly hydrolyzable GTP analogs promote microtubule rescues

Tropini, C., Roth, E. A., Zanic, M., Gardner, M. K. & Howard, J., Jan 17 2012, In : PloS one. 7, 1, e30103.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Depolymerizing kinesins Kip3 and MCAK shape cellular microtubule architecture by differential control of catastrophe

Gardner, M. K., Zanic, M., Gell, C., Bormuth, V. & Howard, J., Nov 23 2011, In : Cell. 147, 5, p. 1092-1103 12 p.

Research output: Contribution to journalArticle

113 Scopus citations

Kif18A uses a microtubule binding site in the tail for plus-end localization and spindle length regulation

Weaver, L. N., Ems-McClung, S. C., Stout, J. R., Leblanc, C., Shaw, S. L., Gardner, M. K. & Walczak, C. E., Sep 13 2011, In : Current Biology. 21, 17, p. 1500-1506 7 p.

Research output: Contribution to journalArticle

63 Scopus citations

Microtubule tip tracking and tip structures at the nanometer scale using digital fluorescence microscopy

Demchouk, A. O., Gardner, M. K. & Odde, D. J., Jun 1 2011, In : Cellular and Molecular Bioengineering. 4, 2, p. 192-204 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Rapid microtubule self-assembly kinetics

Gardner, M. K., Charlebois, B. D., Jánosi, I. M., Howard, J., Hunt, A. J. & Odde, D. J., Aug 19 2011, In : Cell. 146, 4, p. 582-592 11 p.

Research output: Contribution to journalArticle

120 Scopus citations
2010

Erratum: Model convolution: A computational approach to digital image interpretation (Cellular and Molecular Bioengineering (2010) 3:3 (331-332))

Gardner, M. K., Sprague, B. L., Pearson, C. G., Cosgrove, B. D., Bicek, A. D., Bloom, K., Salmon, E. D. & Odde, D. J., Sep 1 2010, In : Cellular and Molecular Bioengineering. 3, 3, p. 331-332 2 p.

Research output: Contribution to journalComment/debate

Model convolution: A computational approach to digital image interpretation

Gardner, M. K., Sprague, B. L., Pearson, C. G., Cosgrove, B. D., Bicek, A. D., Bloom, K., Salmon, E. D. & Odde, D. J., Jun 1 2010, In : Cellular and Molecular Bioengineering. 3, 2, p. 163-170 8 p.

Research output: Contribution to journalReview article

18 Scopus citations

Slk19p of Saccharomyces cerevisiae regulates anaphase spindle dynamics through two independent mechanisms

Havens, K. A., Gardner, M. K., Kamieniecki, R. J., Dresser, M. E. & Dawson, D. S., Dec 1 2010, In : Genetics. 186, 4, p. 1247-1260 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Stochastic simulation and graphic visualization of mitotic processes

Gardner, M. K. & Odde, D. J., Jun 1 2010, In : Methods. 51, 2, p. 251-256 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2008

Chromosome Congression by Kinesin-5 Motor-Mediated Disassembly of Longer Kinetochore Microtubules

Gardner, M. K., Bouck, D. C., Paliulis, L. V., Meehl, J. B., O'Toole, E. T., Haase, J., Soubry, A., Joglekar, A. P., Winey, M., Salmon, E. D., Bloom, K. & Odde, D. J., Nov 28 2008, In : Cell. 135, 5, p. 894-906 13 p.

Research output: Contribution to journalArticle

118 Scopus citations

Dam1 complexes go it alone on disassembling microtubules

Gardner, M. K. & Odde, D. J., Aug 11 2008, In : Nature Cell Biology. 10, 4, p. 379-381 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Kinesin-8 molecular motors: putting the brakes on chromosome oscillations

Gardner, M. K., Odde, D. J. & Bloom, K., Jul 1 2008, In : Trends in Cell Biology. 18, 7, p. 307-310 4 p.

Research output: Contribution to journalShort survey

35 Scopus citations

Microtubule assembly dynamics: new insights at the nanoscale

Gardner, M. K., Hunt, A. J., Goodson, H. V. & Odde, D. J., Feb 1 2008, In : Current Opinion in Cell Biology. 20, 1, p. 64-70 7 p.

Research output: Contribution to journalReview article

49 Scopus citations

The microtubule-based motor Kar3 and plus end-binding protein Bim1 provide structural support for the anaphase spindle

Gardner, M. K., Haase, J., Mythreye, K., Molk, J. N., Anderson, M. B., Joglekar, A. P., O'Toole, E. T., Winey, M., Salmon, E. D., Odde, D. J. & Bloom, K., Jan 14 2008, In : Journal of Cell Biology. 180, 1, p. 91-100 10 p.

Research output: Contribution to journalArticle

53 Scopus citations
2007

Hypothesis testing via integrated computer modeling and digital fluorescence microscopy

Gardner, M. K., Odde, D. J. & Bloom, K., Feb 1 2007, In : Methods. 41, 2, p. 232-237 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Microtubule Assembly Dynamics at the Nanoscale

Schek, H. T., Gardner, M. K., Cheng, J., Odde, D. J. & Hunt, A. J., Sep 4 2007, In : Current Biology. 17, 17, p. 1445-1455 11 p.

Research output: Contribution to journalArticle

127 Scopus citations
2006

Asymmetric Division: Motor Persistence Pays off

Gardner, M. K. & Odde, D. J., Dec 19 2006, In : Current Biology. 16, 24, p. R1021-R1023

Research output: Contribution to journalShort survey

Measuring nanometer scale gradients in spindle microtubule dynamics using model convolution microscopy

Pearson, C. G., Gardner, M. K., Paliulis, L. V., Salmon, E. D., Odde, D. J. & Bloom, K., Sep 1 2006, In : Molecular biology of the cell. 17, 9, p. 4069-4079 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Modeling of chromosome motility during mitosis

Gardner, M. K. & Odde, D. J., Dec 1 2006, In : Current Opinion in Cell Biology. 18, 6, p. 639-647 9 p.

Research output: Contribution to journalReview article

27 Scopus citations

Mps1 Phosphorylation of Dam1 Couples Kinetochores to Microtubule Plus Ends at Metaphase

Shimogawa, M. M., Graczyk, B., Gardner, M. K., Francis, S. E., White, E. A., Ess, M., Molk, J. N., Ruse, C., Niessen, S., Yates, J. R., Muller, E. G. D., Bloom, K., Odde, D. J. & Davis, T. N., Aug 8 2006, In : Current Biology. 16, 15, p. 1489-1501 13 p.

Research output: Contribution to journalArticle

68 Scopus citations
2005

Tension-depenent regulation of microtubule dynamics at kinetochores can explain metaphase congression in yeast

Gardner, M. K., Pearson, C. G., Sprague, B. L., Zarzar, T. R., Bloom, K., Salmon, E. D. & Odde, D. J., Aug 1 2005, In : Molecular biology of the cell. 16, 8, p. 3764-3775 12 p.

Research output: Contribution to journalArticle

100 Scopus citations
2004

Model-convolution approach to modeling fluorescent protein dynamics

Sprague, B. L., Gardner, M. K., Pearson, C. G., Maddox, P. S., Bloom, K., Salmon, E. D. & Odde, D. J., Dec 1 2004, In : Conference Record - Asilomar Conference on Signals, Systems and Computers. 2, p. 1821-1825 5 p.

Research output: Contribution to journalConference article

6 Scopus citations

Stable kinetochore-microtubule attachment constrains centromere positioning in metaphase

Pearson, C. G., Yeh, E., Gardner, M., Odde, D., Salmon, E. D. & Bloom, K., Nov 9 2004, In : Current Biology. 14, 21, p. 1962-1967 6 p.

Research output: Contribution to journalArticle

122 Scopus citations