20132020

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Article
2014

Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ

Yousefzadeh, M. J., Wyatt, D. W., Takata, K. I., Mu, Y., Hensley, S. C., Tomida, J., Bylund, G. O., Doublié, S., Johansson, E., Ramsden, D. A., McBride, K. M. & Wood, R. D., Oct 1 2014, In : PLoS genetics. 10, 10

Research output: Contribution to journalArticle

Open Access
100 Scopus citations
2015

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

Tomida, J., Takata, K. I., Lange, S. S., Schibler, A. C., Yousefzadeh, M. J., Bhetawal, S., Dent, S. Y. R. & Wood, R. D., Jan 30 2015, In : Nucleic acids research. 43, 2, p. 1000-1011 12 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations
2016

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks

Wyatt, D. W., Feng, W., Conlin, M. P., Yousefzadeh, M. J., Roberts, S. A., Mieczkowski, P., Wood, R. D., Gupta, G. P. & Ramsden, D. A., Aug 18 2016, In : Molecular Cell. 63, 4, p. 662-673 12 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations
2017

Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance

Takata, K. I., Reh, S., Yousefzadeh, M. J., Zelazowski, M. J., Bhetawal, S., Trono, D., Lowery, M. G., Sandoval, M., Takata, Y., Lu, Y., Lin, K., Shen, J., Kusewitt, D. F., McBride, K. M., Cole, F. & Wood, R. D., Jan 1 2017, In : PLoS genetics. 13, 6, e1006818.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Circulating levels of monocyte chemoattractant protein-1 as a potential measure of biological age in mice and frailty in humans

Yousefzadeh, M. J., Schafer, M. J., Noren Hooten, N., Atkinson, E. J., Evans, M. K., Baker, D. J., Quarles, E. K., Robbins, P. D., Ladiges, W. C., LeBrasseur, N. K. & Niedernhofer, L. J., Apr 2018, In : Aging cell. 17, 2, e12706.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation

Czerwińska, J., Nowak, M., Wojtczak, P., Dziuban-Lech, D., Cieśla, J. M., Kołata, D., Gajewska, B., Barańczyk-Kuźma, A., Robinson, A. R., Shane, H. L., Gregg, S. Q., Rigatti, L. H., Yousefzadeh, M. J., Gurkar, A. U., McGowan, S. J., Kosicki, K., Bednarek, M., Zarakowska, E., Gackowski, D., Oliński, R. & 3 others, Speina, E., Niedernhofer, L. J. & Tudek, B., Aug 20 2018, In : Free Radical Biology and Medicine. 124, p. 79-96 18 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

ERCC4 variants identified in a cohort of patients with segmental progeroid syndromes

University of Washington Center for Mendelian Genomics, Feb 1 2018, In : Human mutation. 39, 2, p. 255-265 11 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Fisetin is a senotherapeutic that extends health and lifespan

Yousefzadeh, M. J., Zhu, Y., McGowan, S. J., Angelini, L., Fuhrmann-Stroissnigg, H., Xu, M., Ling, Y. Y., Melos, K. I., Pirtskhalava, T., Inman, C. L., McGuckian, C., Wade, E. A., Kato, J. I., Grassi, D., Wentworth, M., Burd, C. E., Arriaga, E. A., Ladiges, W. L., Tchkonia, T., Kirkland, J. L. & 2 others, Robbins, P. D. & Niedernhofer, L. J., Oct 2018, In : EBioMedicine. 36, p. 18-28 11 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

Neurodegeneration as the presenting symptom in 2 adults with xeroderma pigmentosum complementation group F

Shanbhag, N. M., Geschwind, M. D., DiGiovanna, J. J., Groden, C., Godfrey, R., Yousefzadeh, M. J., Wade, E. A., Niedernhofer, L. J., Malicdan, M. C. V., Kraemer, K. H., Gahl, W. A. & Toro, C., Jun 1 2018, In : Neurology: Genetics. 4, 3, e240.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Oxidation products of 5-methylcytosine are decreased in senescent cells andtissues of progeroid mice

Zarakowska, E., Czerwinska, J., Tupalska, A., Yousefzadeh, M. J., Gregg, S. Q., Croix, C. M. S., Niedernhofer, L. J., Foksinski, M., Gackowski, D., Szpila, A., Starczak, M., Tudek, B. & Olinski, R., Jan 1 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 8, p. 1003-1009 7 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging

Robinson, A. R., Yousefzadeh, M. J., Rozgaja, T. A., Wang, J., Li, X., Tilstra, J. S., Feldman, C. H., Gregg, S. Q., Johnson, C. H., Skoda, E. M., Frantz, M. C., Bell-Temin, H., Pope-Varsalona, H., Gurkar, A. U., Nasto, L. A., Robinson, R. A. S., Fuhrmann-Stroissnigg, H., Czerwinska, J., McGowan, S. J., Cantu-Medellin, N. & 22 others, Harris, J. B., Maniar, S., Ross, M. A., Trussoni, C. E., LaRusso, N. F., Cifuentes-Pagano, E., Pagano, P. J., Tudek, B., Vo, N. V., Rigatti, L. H., Opresko, P. L., Stolz, D. B., Watkins, S. C., Burd, C. E., Croix, C. M. S., Siuzdak, G., Yates, N. A., Robbins, P. D., Wang, Y., Wipf, P., Kelley, E. E. & Niedernhofer, L. J., Jul 2018, In : Redox Biology. 17, p. 259-273 15 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
2019

Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis–like symptoms in NOD mice

Flores, R. R., Carbo, L., Kim, E., Van Meter, M., De Padilla, C. M. L., Zhao, J., Colangelo, D., Yousefzadeh, M. J., Angelini, L. A., Zhang, L., Pola, E., Vo, N., Evans, C. H., Gambotto, A., Niedernhofer, L. J. & Robbins, P. D., Aug 1 2019, In : FASEB Journal. 33, 8, p. 9505-9515 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Measuring biological age in mice using differential mass spectrometry

Bell-Temin, H., Yousefzadeh, M. J., Bondarenko, A., Quarles, E., Jones-Laughner, J., Robbins, P. D., Ladiges, W., Niedernhofer, L. J. & Yates, N. A., Jan 1 2019, In : Aging. 11, 3, p. 1045-1061 17 p.

Research output: Contribution to journalArticle

Open Access
2020

ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging

Zhao, J., Zhang, L., Lu, A., Han, Y., Colangelo, D., Bukata, C., Scibetta, A., Yousefzadeh, M., Li, X., Gurkar, A. U., McGowan, S. J., Angelini, L., O'Kelly, R., Li, H., Corbo, L., Sano, T., Nick, H., Pola, E., Pilla, S. P. S., Ladiges, W. C. & 4 others, Vo, N., Huard, J., Niedernhofer, L. J. & Robbins, P. D., Mar 31 2020, In : Aging. 12, 6, p. 4688-4710 23 p.

Research output: Contribution to journalArticle

Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues

Yousefzadeh, M. J., Wilkinson, J. E., Hughes, B., Gadela, N., Ladiges, W. C., Vo, N., Niedernhofer, L. J., Huffman, D. M. & Robbins, P. D., Jun 1 2020, In : GeroScience. 42, 3, p. 951-961 11 p.

Research output: Contribution to journalArticle

Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice

Yousefzadeh, M., Zhao, J., Bukata, C., Wade, E. A., McGowan, S. J., Angelini, L., Bank, M. P., Gurkar, A. U., McGuckian, C. A., Calubag, M. F., Kato, J. I., Burd, C. E., Robbins, P. D. & Niedernhofer, L. J., Mar 1 2020, In : Aging cell. 19, 3, e13094.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations