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Personal profile

Research interests

I am an emerging pathogen biologist who uses a cross disciplinary approach to address a wide variety of questions regarding the host response (both the invertebrate and vertebrate host) to RNA virus (arthropod-borne viruses) infection, with a particular focus on the dynamics of host-virus interactions. My research program is directed at providing a more comprehensive understanding of the factors that govern host shifts, geographic expansions, and the emergence/re-emergence of arthropod-borne viruses. The overall goal of which is to develop strategies to interrupt transmission or predict a zoonotic pathogen’s adaptability or evolvability. I have extensive experience in arbovirus virology, vector biology, and animal model development.

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Projects

Research Output

Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques

Breitbach, M. E., Newman, C. M., Dudley, D. M., Stewart, L. M., Aliota, M. T., Koenig, M. R., Shepherd, P. M., Yamamoto, K., Crooks, C. M., Young, G., Semler, M. R., Weiler, A. M., Barry, G. L., Heimsath, H., Mohr, E. L., Eichkoff, J., Newton, W., Peterson, E., Schultz-Darken, N., Permar, S. R. & 5 others, Dean, H., Capuano, S., Osorio, J. E., Friedrich, T. C. & O'Connor, D. H., Jan 1 2019, In : PLoS pathogens. 15, 8, e1007766.

Research output: Contribution to journalArticle

Open Access
  • 3 Scopus citations

    Tracking dengue virus type 1 genetic diversity during lineage replacement in an hyperendemic area in Colombia

    Salvo, M. A., Aliota, M. T., Moncla, L. H., Velez, I. D., Trujillo, A. I., Friedrich, T. C. & Osorio, J. E., Mar 2019, In : PloS one. 14, 3, e0212947.

    Research output: Contribution to journalArticle

    Open Access
  • Using Macaques to Address Critical Questions in Zika Virus Research

    Dudley, D. M., Aliota, M. T., Mohr, E. L., Newman, C. M., Golos, T. G., Friedrich, T. C. & O'Connor, D. H., Sep 29 2019, In : Annual Review of Virology. 6, p. 481-500 20 p.

    Research output: Contribution to journalArticle

  • Zika viruses of African and Asian lineages cause fetal harm in a mouse model of vertical transmission

    Jaeger, A. S., Murrieta, R. A., Goren, L., M. Crooks, C., Moriarty, R. V., Weiler, A. M., Rybarczyk, S., Semler, M. R., Huffman, C., Mejia, A., Simmons, H. A., Fritsch, M., Osorio, J. E., Eickhoff, J. C., O'Connor, S. L., Ebel, G. D., Friedrich, T. C. & Aliota, M. T., Apr 2019, In : PLoS Neglected Tropical Diseases. 13, 4, e0007343.

    Research output: Contribution to journalArticle

    Open Access
  • 4 Scopus citations

    Zika virus replication and cytopathic effects in liver cells

    Sherman, K. E., Rouster, S. D., Kong, L. X., Aliota, M. T., Blackard, J. T. & Dean, G. E., Mar 2019, In : PloS one. 14, 3, e0214016.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations