Projects per year
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Research interests
Miller Lab Consortium. To date, our team has treated more than 400 patients with natural killer cell infusions and over a hundred patients with therapies that activate their own natural killer cells. We've retrospectively analyzed more than 5000 patients and enrolled more than 500 patients in prospective trials.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Evaluation of Novel TriKE-PACC Molecule to Amplify Natural Killer Cell Function in Mesothelioma
Felices, M. (PI) & Miller, J. S. (CoI)
7/15/24 → 7/14/26
Project: Research project
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Leveraging Targeted Biological Complexes to Maximize Natural Killer Cell Immunotherapy in Lung Cancer
Felices, M. (PI), Fujioka, N. (CoI) & Miller, J. S. (CoI)
7/1/24 → 6/30/27
Project: Research project
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Trapping Inhibitory Signals in Synergy with Cytokine Signaling to Maximize NK Cell Immunotherapy in Ovarian Cancer
Felices, M. (PI) & Miller, J. S. (CoI)
7/1/24 → 6/30/28
Project: Research project
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Cancer Center Support Grant
Yee, D. (PI), Antonarakis, E. (CoI), Beckman, K. B. (CoI), Betts, B. (CoI), Blaes, A. H. (CoI), Eaton, A. (CoI), Ellis, K. M. (CoI), Felices, M. (CoI), Geller, M. A. (CoI), Ghebre, R. G. (CoI), Griffin, T. J. (CoI), Hallstrom, T. C. (CoI), Harki, D. A. (CoI), Hatsukami, D. K. (CoI), Hirsch, B. A. (CoI), Huang, R. S. S. (CoI), Johnson, S. (CoI), Juckett, M. B. (CoI), Lange, C. A. (CoI), Le, C. T. (CoI), Luo, X. (CoI), McKenna, D. H. (CoI), Miller, J. S. (CoI), Moriarity, B. S. (CoI), Muretta, J. M. (CoI), Murray, T. (CoI), Nelson, H. H. (CoI), Ondrey, F. G. (CoI), Patel, M. R. (CoI), Pennell, C. A. (CoI), Petersen, A. J. (CoI), Peterson, L. A. (CoI), Poynter, J. (CoI), Pratt, R. J. (CoI), Sarver, A. L. (CoI), Schendzielos, D. L. (CoI), Schilz, A. (CoI), Schwertfeger, K. (CoI), Seelig, D. (CoI), Shimizu, Y. (CoI), Stepanov, I. (CoI), Temiz, N. A. (CoI), Ventz, S. (CoI), Villalta, P. W. (CoI), Vogel, R. (CoI), Wagner, J. E. (CoI), Wang, J. (CoI), Webber, B. R. (CoI), Weigel, B. J. (CoI), Yamamoto, M. (CoI) & Zhang, L. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
2/1/24 → 1/31/29
Project: Research project
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Targeting off-the-shelf iPSC-derived natural killer cells against solid tumors
Miller, J. S. (PI), Antonarakis, E. (CoI), Chen, C. C. (CoI), Cichocki, F. M. (CoI), Davis, Z. B. (CoI), Dehm, S. M. (CoI), Felices, M. (CoI), Luo, X. (CoI) & Provenzano, P. (CoI)
NIH NATIONAL CANCER INSTITUTE (NCI)
8/1/23 → 7/31/30
Project: Research project
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A PSMA-Targeted Tri-Specific Killer Engager Enhances NK Cell Cytotoxicity against Prostate Cancer
Phung, S. K., Zorko, N. A., Soignier, Y., Waller, R. L., Shackelford, M., Walker, J. T., Nelson, T. D., Selleck, C., Bendzick, L. E., Kotz, L. E., Kile, Q. M., Bozicevich, A. J., Miller, S. E., Khaw, M., Shetty, M., Hinderlie, P., Ehrhardt, M., Li, Y., Luo, X. & Dehm, S. M. & 4 others, , Feb 1 2025, In: Cancer Immunology Research. 13, 2, p. 258-272 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
CD56bright cytokine-induced memory-like NK cells and NK-cell engagers synergize against non-small cell lung cancer cancer-stem cells
Guevara Lopez, M. L., Gebo, A., Parodi, M., Persano, S., Maus-Conn, J., Mingari, M. C., Loiacono, F., Orecchia, P., Sivori, S., Cantoni, C., Gentili, M., Facchinetti, F., Ferracini, R., Vallera, D. A., Felices, M., Bertolini, G., Pravetoni, M., Roz, L. & Vitale, M., Feb 12 2025, In: Journal for ImmunoTherapy of Cancer. 13, 2, e010205.Research output: Contribution to journal › Article › peer-review
Open Access -
Natural Killer Cell Infiltration in Prostate Cancers Predict Improved Patient Outcomes
Zorko, N. A., Makovec, A., Elliott, A., Kellen, S., Lozada, J. R., Arafa, A. T., Felices, M., Shackelford, M., Barata, P., Zakharia, Y., Narayan, V., Stein, M. N., Zarrabi, K. K., Patniak, A., Bilen, M. A., Radovich, M., Sledge, G., El-Deiry, W. S., Heath, E. I. & Hoon, D. S. B. & 4 others, , Mar 2025, In: Prostate Cancer and Prostatic Diseases. 28, 1, p. 129-137 9 p., 34.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Enhanced IL-15-mediated NK cell activation and proliferation by an ADAM17 function-blocking antibody involves CD16A, CD137, and accessory cells
Matson, A. W., Hullsiek, R., Dixon, K. J., Wang, S., Lindstedt, A. J., Friess, R. R., Phung, S. K., Freedman, T. S., Felices, M., Truckenbrod, E. N., Wu, J., Miller, J. S. & Walcheck, B., Jul 24 2024, In: Journal for ImmunoTherapy of Cancer. 12, 7, e008959.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Metabolic programs drive function of therapeutic NK cells in hypoxic tumor environments
Kennedy, P., Arvindam, U. S., Phung, S. K., Ettestad, B., Feng, X., Li, Y., Kile, Q. M., Hinderlie, P., Khaw, M., Huang, R. S., Kaufman, M., Puchalska, P., Russell, A., Butler, J., Abbott, L., McClure, P., Luo, X., Lu, Q. T., Blazar, B. R. & Crawford, P. & 3 others, , Nov 1 2024, In: Science Advances. 10, 44, eadn1849.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations