Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Immune Cell therapy for RDEB
Tolar, J. (PI) & Osborn, M. J. (CoI)
7/22/24 → 7/21/25
Project: Research project
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Wastewater Surveillance Testing
Osborn, M. J. (PI) & Doss, C. R. (CoI)
MN DEPARTMENT OF HEALTH, U.S. DEPARTMENT OF HEALTH & HUMAN SVCS
4/8/24 → 7/31/25
Project: Research project
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Base Editing and Prime Editing for HIV/SCD Cures
Osborn, M. J. (PI)
THE BROAD INSTITUTE, INC., BILL & MELINDA GATES FOUNDATION
10/1/23 → 9/30/26
Project: Research project
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Development of an Off the Shelf Erythrocyte-Based Resuscitation Fluid for Hemostasis and Improved Oxygen Delivery
Osborn, M. J. (PI)
THE HENRY M. JACKSON FOUNDATION, U.S. DEPARTMENT OF DEFENSE
9/30/23 → 9/29/27
Project: Research project
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Enhancing Treg Therapeutic Efficacy in GVHD
Blazar, B. R. (PI), Griffin, T. J. (CoI), Hippen, K. L. (CoI) & Osborn, M. J. (CoI)
NIH NAT'L HEART, LUNG, AND BLOOD INSTITU
5/15/22 → 3/31/26
Project: Research project
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Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice
Saha, A., Palchaudhuri, R., Lanieri, L., Hyzy, S., Riddle, M. J., Panthera, J., Eide, C. R., Tolar, J., Panoskaltsis-Mortari, A., Gorfinkel, L., Tkachev, V., Gerdemann, U., Alvarez-Calderon, F., Palato, E. R., MacMillan, M. L., Wagner, J. E., Kean, L. S., Osborn, M. J., Kiem, H. P. & Scadden, D. T. & 2 others, , May 23 2024, In: Blood. 143, 21, p. 2201-2216 16 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing
Pandey, S., Gao, X. D., Krasnow, N. A., McElroy, A., Tao, Y. A., Duby, J. E., Steinbeck, B. J., McCreary, J., Pierce, S. E., Tolar, J., Meissner, T. B., Chaikof, E. L., Osborn, M. J. & Liu, D. R., 2024, (Accepted/In press) In: Nature Biomedical Engineering.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa
Steinbeck, B. J., Gao, X. D., McElroy, A. N., Pandey, S., Doman, J. L., Riddle, M. J., Xia, L. H., Chen, W., Eide, C. R., Lengert, A. H., Han, S. W., Blazar, B. R., Wandall, H. H., Dabelsteen, S., Liu, D. R., Tolar, J. & Osborn, M. J., Dec 2024, In: Journal of Investigative Dermatology. 144, 12, p. 2764-2777.e9Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Wastewater Surveillance of SARS-CoV-2 in Minnesota
Osborn, M. J., Champeau, S., Meyer, C. M., Hayden, M., Landini, L., Stark, S., Preekett, S., Vetter, S. M., Zirnhelt, Z., Meyer, S., Huff, D., Schacker, T. W. & Doss, C. R., Feb 2024, In: Water (Switzerland). 16, 4, 541.Research output: Contribution to journal › Article › peer-review
Open Access -
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity
Larson, J. H., Jin, S., Loschi, M., Bolivar Wagers, S., Thangavelu, G., Zaiken, M. C., Mcdonald-Hyman, C. S., Saha, A., Aguilar, E., Koehn, B., Osborn, M. J., Panoskaltsis-Mortari, A., Macdonald, K. P. A., Hill, G. R., Murphy, W. J., Serody, J. S., Maillard, I., Kean, L. S., Kim, S. V. & Littman, D. R. & 1 others, , Aug 1 2023, In: American Journal of Transplantation. 23, 8, p. 1102-1115 14 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Press/Media
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U of M working on new COVID-19 test that would take just hours for results
6/3/20
1 item of Media coverage
Press/Media: Research