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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 1 Finished
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Molecular Probes of AGRP for Drug Discovery
NIH Natl Inst of Diabetes/Dig/Kidney Dis
12/1/15 → 11/30/18
Project: Research project
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Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R
Ericson, M. D., Haslach, E. M., Schnell, S. M., Freeman, K. T., Xiang, Z. M., Portillo, F. P., Speth, R., Litherland, S. A. & Haskell-Luevano, C., Feb 3 2021, In: ACS Chemical Neuroscience. 12, 3, p. 542-556 15 p.Research output: Contribution to journal › Article › peer-review
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Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "unbiased" Screening Campaign
Doering, S. R., Freeman, K., Debevec, G., Geer, P., Santos, R. G., Lavoi, T. M., Giulianotti, M. A., Pinilla, C., Appel, J. R., Houghten, R. A., Ericson, M. D. & Haskell-Luevano, C., May 13 2021, In: Journal of medicinal chemistry. 64, 9, p. 5577-5592 16 p.Research output: Contribution to journal › Article › peer-review
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Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist
Ericson, M. D., Shaikh, R., Larson, C., Freeman, K. T. & Haskell-Luevano, C., Jan 14 2021, In: ACS Medicinal Chemistry Letters. 12, 1, p. 115-120 6 p.Research output: Contribution to journal › Article › peer-review
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The melanocortin pathway and energy homeostasis: From discovery to obesity therapy
Yeo, G. S. H., Chao, D. H. M., Siegert, A. M., Koerperich, Z. M., Ericson, M. D., Simonds, S. E., Larson, C. M., Luquet, S., Clarke, I., Sharma, S., Clément, K., Cowley, M. A., Haskell-Luevano, C., Van Der Ploeg, L. & Adan, R. A. H., Jun 2021, In: Molecular Metabolism. 48, 101206.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Comparative intracerebroventricular and intrathecal administration of a nanomolar macrocyclic melanocortin receptor agonist MDE6- 5-2c (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro]) decreases food intake in mice
Haskell-Luevano, C., Adank, D. N., Lunzer, M. M., Ericson, M. D., Koeperich, Z. M., Wilber, S. L. & Fleming, K. A., Oct 7 2020, In: ACS Chemical Neuroscience. 11, 19, p. 3051-3063 13 p.Research output: Contribution to journal › Article › peer-review