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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 1 Finished
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Molecular Probes of AGRP for Drug Discovery
Ericson, M. D. (PI)
NIH NATL INST OF DIABETES/DIG/KIDNEY DIS
12/1/15 → 11/30/18
Project: Research project
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Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]
Ericson, M. D., Freeman, K. T., Larson, C. M., Bouchard, J. L., John, K., Lunzer, M. M., Koerperich, Z. M. & Haskell-Luevano, C., Apr 12 2024, In: ACS Pharmacology and Translational Science. 7, 4, p. 1114-1125 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2′)-Orn-NH2] at the MC1R, MC3R, MC4R, and MC5R that Mediates an Increased Feeding Response in Mice and a 40-Fold Selective MC1R Antagonist [Ac-DPhe(pI)-DArg-Nal(2′)-Arg-NH2]
Ericson, M. D., Tran, L. T., Mathre, S. S., Freeman, K. T., Holdaway, K., John, K., Lunzer, M. M., Bouchard, J. L. & Haskell-Luevano, C., Jun 22 2023, In: Journal of medicinal chemistry. 66, 12, p. 8103-8117 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Erratum: Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High Throughput 'Unbiased' Screening Campaign (J. Med. Chem. (2021) 64:9 (5577−5592) DOI: 10.1021/acs.jmedchem.0c02041)
Doering, S. R., Freeman, K., Debevec, G., Geer, P., Santos, R. G., Lavoi, T. M., Giulianotti, M. A., Pinilla, C., Appel, J. R., Houghten, R. A., Ericson, M. D. & Haskell-Luevano, C., May 25 2023, In: Journal of medicinal chemistry. 66, 10, p. 7063-7065 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
The Parallel Structure–Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands
Ericson, M. D., Freeman, K. T., LaVoi, T. M., Donow, H. M., Santos, R. G., Giulianotti, M. A., Pinilla, C., Houghten, R. A. & Haskell-Luevano, C., Jun 2023, In: International journal of molecular sciences. 24, 12, 10145.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Incorporation of Indoylated Phenylalanine Yields a Sub-Micromolar Selective Melanocortin-4 Receptor Antagonist Tetrapeptide
Ericson, M. D., Larson, C. M., Freeman, K. T., Nicke, L., Geyer, A. & Haskell-Luevano, C., Aug 9 2022, In: ACS Omega. 7, 31, p. 27656-27663 8 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations