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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Projects
- 1 Finished
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Molecular Probes of AGRP for Drug Discovery
NIH Natl Inst of Diabetes/Dig/Kidney Dis
12/1/15 → 11/30/18
Project: Research project
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Incorporation of Indoylated Phenylalanine Yields a Sub-Micromolar Selective Melanocortin-4 Receptor Antagonist Tetrapeptide
Ericson, M. D., Larson, C., Freeman, K. T., Nicke, L., Geyer, A. & Haskell-Luevano, C., Aug 9 2022, In: ACS Omega. 7, 31, p. 27656-27663 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R
Ericson, M. D., Haslach, E. M., Schnell, S. M., Freeman, K. T., Xiang, Z. M., Portillo, F. P., Speth, R., Litherland, S. A. & Haskell-Luevano, C., Feb 3 2021, In: ACS Chemical Neuroscience. 12, 3, p. 542-556 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput "unbiased" Screening Campaign
Doering, S. R., Freeman, K., Debevec, G., Geer, P., Santos, R. G., Lavoi, T. M., Giulianotti, M. A., Pinilla, C., Appel, J. R., Houghten, R. A., Ericson, M. D. & Haskell-Luevano, C., May 13 2021, In: Journal of medicinal chemistry. 64, 9, p. 5577-5592 16 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Functional Mixture-Based Positional Scan Identifies a Library of Antagonist Tetrapeptide Sequences (LAtTeS) with Nanomolar Potency for the Melanocortin-4 Receptor and Equipotent with the Endogenous AGRP(86-132) Antagonist
Ericson, M. D., Doering, S. R., Larson, C. M., Freeman, K. T., Lavoi, T. M., Donow, H. M., Santos, R. G., Cho, R. H., Koerperich, Z. M., Giulianotti, M. A., Pinilla, C., Houghten, R. A. & Haskell-Luevano, C., Oct 14 2021, In: Journal of medicinal chemistry. 64, 19, p. 14860-14875 16 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Multiresidue Tetrapeptide Substitutions Yield a 140-fold Selective Melanocortin-3 over Melanocortin-4 Receptor Agonist
Ericson, M. D., Shaikh, R., Larson, C., Freeman, K. T. & Haskell-Luevano, C., Jan 14 2021, In: ACS Medicinal Chemistry Letters. 12, 1, p. 115-120 6 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations