Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Preparation of peptides that could monitor the related enzymatic reaction catalyzed by the mammalian homolog, ZMPSTE24.
Distefano, M. D. (PI)
UNIVERSITY OF CALIFORNIA SAN DIEGO
1/1/25 → 12/31/25
Project: Research project
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Probing the chemical biology of protein prenylation
Distefano, M. D. (PI)
NIH NIGMS NATL INST OF GENERAL
4/5/21 → 1/31/26
Project: Research project
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Regulation of the small GTPase prenylome by SmgGDS during neuronal development
Distefano, M. D. (PI)
7/1/21 → 6/30/24
Project: Research project
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Mechanism and clinical application of statin/venetoclax combinations in blood cancer
Distefano, M. D. (PI)
UNIVERSITY OF CALIFORNIA, IRVINE, U.S. DEPARTMENT OF DEFENSE
9/1/20 → 8/31/23
Project: Research project
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An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold Is a Biologically Functional Universal Probe for Proteomic Analysis
Auger, S. A., Pedersen, J. S., Maity, S., Sprague-Getsy, A. M., Lorimer, E. L., Koehn, O. J., Krauklis, S. A., Berns, B., Murphy, K. M., Hussain, J., Thao, P., Bernhagen, K., Justyna, K., Sundaresan, A. P., McKim, D. B., Williams, C. L., Hougland, J. L., Li, L. & Distefano, M. D., Jan 7 2025, In: Biochemistry. 64, 1, p. 138-155 18 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Engineering protein prenylation: an emerging tool for selective protein modification
Venkatachalapathy, S., Lichtenfels, C., Wagner, C. R. & Distefano, M. D., Aug 2025, In: Biochemical Society transactions. 53, 4, p. 1129-1149 21 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
In Vivo Metabolic Labeling with an Isoprenoid Probe Reveals APOE Allele-Specific Differences in the Prenylome
Petre, A. M., Thieschafer, J. S., Palsuledesai, C., Cornille, K., Chang, A., Li, L. & Distefano, M. D., Aug 15 2025, In: ACS Chemical Biology. 20, 8, p. 1951-1961 11 p.Research output: Contribution to journal › Article › peer-review
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Profiling of C-terminal prenylated proteins using tandem mass tagging
Kottala, H., Chen, Y. & Distefano, M. D., Jan 2025, Protein Termini - Part B. Arnesen, T. (ed.). Academic Press Inc., p. 317-345 29 p. (Methods in Enzymology; vol. 719).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Upstream Proteolysis by Ste24 does not Require a C-Terminal Methyl Ester as Revealed Using 33-Residue a-Factor Precursor Peptide Substrates Synthesized via Epimerization-Free Methods
Bader, T. K., Brown, S. M., Hrycyna, C. A. & Distefano, M. D., Mar 2025, In: International Journal of Peptide Research and Therapeutics. 31, 2, 17.Research output: Contribution to journal › Article › peer-review
Datasets
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Supporting data for Polymeric medical sutures: An exploration of polymers and green chemistry
Distefano, M. D., Javner, C. H., Knutson, C. M., Schneiderman, D. K., Wissinger, J. E. & Yu, M., Data Repository for the University of Minnesota, 2018
http://hdl.handle.net/11299/192814
Dataset