Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Probing the chemical biology of protein prenylation
Distefano, M. D. (PI)
NIH NIGMS NATL INST OF GENERAL
4/5/21 → 1/31/26
Project: Research project
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Regulation of the small GTPase prenylome by SmgGDS during neuronal development
Distefano, M. D. (PI)
7/1/21 → 6/30/24
Project: Research project
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Mechanism and clinical application of statin/venetoclax combinations in blood cancer
Distefano, M. D. (PI)
UNIVERSITY OF CALIFORNIA, IRVINE, U.S. DEPARTMENT OF DEFENSE
9/1/20 → 8/31/23
Project: Research project
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Mechanism of Ste24, a Novel Integral Membrane Zinc Metalloprotease that Promotes Catalysis Within an Intramembrane Chamber
Distefano, M. D. (PI)
THE NATIONAL SCIENCE FOUNDATION
7/15/19 → 6/30/23
Project: Research project
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An Alkyne-Containing Isoprenoid Analogue Based on a Farnesyl Diphosphate Scaffold Is a Biologically Functional Universal Probe for Proteomic Analysis
Auger, S. A., Pedersen, J. S., Maity, S., Sprague-Getsy, A. M., Lorimer, E. L., Koehn, O. J., Krauklis, S. A., Berns, B., Murphy, K. M., Hussain, J., Thao, P., Bernhagen, K., Justyna, K., Sundaresan, A. P., McKim, D. B., Williams, C. L., Hougland, J. L., Li, L. & Distefano, M. D., 2024, (Accepted/In press) In: Biochemistry.Research output: Contribution to journal › Article › peer-review
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Broadening the Utility of Farnesyltransferase-Catalyzed Protein Labeling Using Norbornene-Tetrazine Click Chemistry
Auger, S. A., Venkatachalapathy, S., Suazo, K. F. G., Wang, Y., Sarkis, A. W., Bernhagen, K., Justyna, K., Schaefer, J. V., Wollack, J. W., Plückthun, A., Li, L. & Distefano, M. D., Jul 17 2024, In: Bioconjugate Chemistry. 35, 7, p. 922-933 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors
Suazo, K. F. G., Mishra, V., Maity, S., Auger, S. A., Justyna, K., Petre, A. M., Ottoboni, L., Ongaro, J., Corti, S. P., Lotti, F., Przedborski, S. & Distefano, M. D., Jun 2024, In: Bioorganic Chemistry. 147, 107365.Research output: Contribution to journal › Article › peer-review
Open Access -
Library Screening, In Vivo Confirmation, and Structural and Bioinformatic Analysis of Pentapeptide Sequences as Substrates for Protein Farnesyltransferase
Schey, G. L., Hildebrandt, E. R., Wang, Y., Diwan, S., Passetti, H. A., Potts, G. W., Sprague-Getsy, A. M., Leoni, E. R., Kuebler, T. S., Sham, Y. Y., Hougland, J. L., Beese, L. S., Schmidt, W. K. & Distefano, M. D., May 2024, In: International journal of molecular sciences. 25, 10, 5324.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Mononuclear phagocyte morphological response to chemoattractants is dependent on geranylgeranyl pyrophosphate
Krauklis, S. A., Hussain, J., Murphy, K. M., Dray, E. L., Ousley, C. G., Justyna, K., Distefano, M. D., Steelman, A. J. & McKim, D. B., Jul 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 327, 1, p. E55-E68Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Datasets
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Supporting data for Polymeric medical sutures: An exploration of polymers and green chemistry
Distefano, M. D., Javner, C. H., Knutson, C. M., Schneiderman, D. K., Wissinger, J. E. & Yu, M., Data Repository for the University of Minnesota, 2018
http://hdl.handle.net/11299/192814
Dataset