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Research Output 1982 2018

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Article
2018
6 Citations (Scopus)

Myosin-driven intracellular transport

Titus, M. A., Mar 1 2018, In : Cold Spring Harbor Perspectives in Biology. 10, 3, a021972.

Research output: Contribution to journalArticle

Myosins
Actins
Fungi
Actin Cytoskeleton
Chemical activation
2017
2 Citations (Scopus)

Growing, splitting and stacking myosin II filaments

Titus, M. A., Jan 31 2017, In : Nature Cell Biology. 19, 2, p. 77-79 3 p.

Research output: Contribution to journalArticle

Myosin Type II
Stress Fibers
Actin Cytoskeleton
Actins
8 Citations (Scopus)

Myosin 7 and its adaptors link cadherins to actin

Yu, I. M., Planelles-Herrero, V. J., Sourigues, Y., Moussaoui, D., Sirkia, H., Kikuti, C., Stroebel, D., Titus, M. A. & Houdusse, A., Jun 29 2017, In : Nature communications. 8, 15864.

Research output: Contribution to journalArticle

Open Access
Stereocilia
myosins
Cadherins
Myosins
Actins
2016
17 Citations (Scopus)

Coordinated recruitment of spir actin nucleators and myosin V motors to rab11 vesicle membranes

Pylypenko, O., Welz, T., Tittel, J., Kollmar, M., Chardon, F., Malherbe, G., Weiss, S., Michel, C. I. L., Samol-Wolf, A., Grasskamp, A. T., Hume, A., Goud, B., Baron, B., England, P., Titus, M. A., Schwille, P., Weidemann, T., Houdusse, A. & Kerkhoff, E., Sep 13 2016, In : eLife. 5, September, e17523.

Research output: Contribution to journalArticle

Myosin Type V
Actins
Membranes
Myosins
rab GTP-Binding Proteins
9 Citations (Scopus)

Myosin MyTH4-FERM structures highlight important principles of convergent evolution

Planelles-Herrero, V. J., Blanc, F., Sirigu, S., Sirkia, H., Clause, J., Sourigues, Y., Johnsrud, D. O., Amigues, B., Cecchini, M., Gilbert, S. P., Houdusse, A. & Titus, M. A., May 24 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. E2906-E2915

Research output: Contribution to journalArticle

Myosins
Microtubules
Tail
Binding Sites
Pseudopodia
6 Citations (Scopus)

MyTH4-FERM myosins have an ancient and conserved role in filopod formation

Petersen, K. J., Goodson, H. V., Arthur, A. L., Luxton, G. W. G., Houdusse, A., Titus, M. A. & Devreotes, P. N., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8059-E8068

Research output: Contribution to journalArticle

Myosins
Pseudopodia
Amoebozoa
Null Lymphocytes
Amoeba
7 Citations (Scopus)

Selective localization of myosin-I proteins in macropinosomes and actin waves

Brzeska, H., Koech, H., Pridham, K. J., Korn, E. D. & Titus, M. A., Feb 1 2016, In : Cytoskeleton. 73, 2, p. 68-82 15 p.

Research output: Contribution to journalArticle

Myosin Type I
Actins
Myosins
Proteins
Dictyostelium
2014
13 Citations (Scopus)

The association of myosin IB with actin waves in dictyostelium requires both the plasma membrane-binding site and actin-binding region in the myosin tail

Brzeska, H., Pridham, K., Chery, G., Titus, M. A. & Korn, E. D., Apr 18 2014, In : PloS one. 9, 4, e94306.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Cell membranes
Myosins
myosin
2013
40 Citations (Scopus)

Structural basis of myosin v Rab GTPase-dependent cargo recognition

Pylypenko, O., Attanda, W., Gauquelin, C., Lahmani, M., Coulibaly, D., Baron, B., Hoos, S., Titus, M. A., England, P. & Houdusse, A. M., Dec 17 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 51, p. 20443-20448 6 p.

Research output: Contribution to journalArticle

rab GTP-Binding Proteins
Myosins
Protein Isoforms
Melanosomes
Membranes
2012
6 Citations (Scopus)

Allosteric communication in Dictyostelium myosin II

Guhathakurta, P., Prochniewicz-Nakayama, E., Muretta, J. M., Titus, M. A. & Thomas, D. D., Oct 1 2012, In : Journal of Muscle Research and Cell Motility. 33, 5, p. 305-312 8 p.

Research output: Contribution to journalArticle

Myosin Type II
Dictyostelium
Myosins
Actins
Adenosine Diphosphate
9 Citations (Scopus)

Molecular basis of dynamic relocalization of Dictyostelium Myosin IB

Brzeska, H., Guag, J., Preston, G. M., Titus, M. A. & Korn, E. D., Apr 27 2012, In : Journal of Biological Chemistry. 287, 18, p. 14923-14936 14 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Molecular Dynamics Simulation
Cell membranes
Myosins
2011
10 Citations (Scopus)

Characterization of a myosin VII MyTH/FERM domain

Moen, R. J., Johnsrud, D. O., Thomas, D. D. & Titus, M. A., Oct 14 2011, In : Journal of Molecular Biology. 413, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

Myosins
Microtubules
Dictyostelium
Deafness
Cytoskeleton

Cytoskeletons by the sea

Titus, M. A., Mar 1 2011, In : EMBO Reports. 12, 3, p. 185-187 3 p.

Research output: Contribution to journalArticle

Cytoskeletal Proteins
Cytoskeleton
Oceans and Seas
Coastal zones
Molecules
15 Citations (Scopus)

Structural and functional impact of site-directed methionine oxidation in myosin

Klein, J. C., Moen, R. J., Smith, E. A., Titus, M. A. & Thomas, D. D., Nov 29 2011, In : Biochemistry. 50, 47, p. 10318-10327 10 p.

Research output: Contribution to journalArticle

Myosins
Methionine
Actins
Oxidation
Dictyostelium
39 Citations (Scopus)

Structural kinetics of myosin by transient time-resolved FRET

Nesmelov, Y. E., Agafonov, R. V., Negrashov, I. V., Blakely, S. E., Titus, M. A. & Thomas, D. D., Feb 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 5, p. 1891-1896 6 p.

Research output: Contribution to journalArticle

Myosins
Molecular Motor Proteins
Adenosine Triphosphate
Fluorescence
Stroke
2010
16 Citations (Scopus)

An unconventional myosin required for cell polarization and chemotaxis

Breshears, L. M., Wessels, D., Soll, D. R. & Titus, M. A., Apr 13 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 15, p. 6918-6923 6 p.

Research output: Contribution to journalArticle

Chemotaxis
Myosins
Actins
Stereocilia
Cell Polarity
2009
48 Citations (Scopus)

Structural dynamics of the myosin relay helix by time-resolved EPR and FRET

Agafonov, R. V., Negrashov, I. V., Tkachev, Y. V., Blakely, S. E., Titus, M. A., Thomas, D. D. & Nesmelov, Y. E., Dec 22 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 51, p. 21625-21630 6 p.

Research output: Contribution to journalArticle

Myosins
Stroke
Adenosine Diphosphate
Nucleotides
Adenosine Triphosphate
17 Citations (Scopus)

The Dictyostelium type V myosin MyoJ is responsible for the cortical association and motility of contractile vacuole membranes

Jung, G., Titus, M. A. & Hammer, J. A., Aug 24 2009, In : Journal of Cell Biology. 186, 4, p. 555-570 16 p.

Research output: Contribution to journalArticle

Myosin Type V
Dictyostelium
Vacuoles
Membranes
Null Lymphocytes
2008
37 Citations (Scopus)

Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR

Klein, J. C., Burr, A. R., Svensson, B., Kennedy, D. J., Allingham, J., Titus, M. A., Rayment, I. & Thomas, D. D., Sep 2 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12867-12872 6 p.

Research output: Contribution to journalArticle

Myosin Type II
Electron Spin Resonance Spectroscopy
Actins
Cysteine
Nucleotides
23 Citations (Scopus)
Spin Labels
Myosins
Muscles
Dictyostelium
Electron Spin Resonance Spectroscopy
2007
10 Citations (Scopus)

Talin influences the dynamics of the myosin VII-membrane interaction

Galdeen, S. A., Stephens, S., Thomas, D. D. & Titus, M. A., Oct 1 2007, In : Molecular Biology of the Cell. 18, 10, p. 4074-4084 11 p.

Research output: Contribution to journalArticle

Talin
Myosins
Dictyostelium
Membranes
Green Fluorescent Proteins
8 Citations (Scopus)

The SH3 domain of a M7 interacts with its C-terminal proline-rich region

Wang, Q., Deloia, M. A., Kang, Y., Litchke, C., Zhang, N., Titus, M. A. & Walters, K. J., Feb 1 2007, In : Protein Science. 16, 2, p. 189-196 8 p.

Research output: Contribution to journalArticle

src Homology Domains
Proline
Myosins
Proteins
Myosin Type I
2006
19 Citations (Scopus)

Structural dynamics of the actin-myosin interface by site-directed spectroscopy

Korman, V. L., Anderson, S. E. B., Prochniewicz-Nakayama, E., Titus, M. A. & Thomas, D. D., Mar 10 2006, In : Journal of Molecular Biology. 356, 5, p. 1107-1117 11 p.

Research output: Contribution to journalArticle

Myosins
Actins
Spectrum Analysis
Actomyosin
Fluorescence
2005
24 Citations (Scopus)

Identification of a myosin VII-talin complex

Tuxworth, R. I., Stephens, S., Ryan, Z. C. & Titus, M. A., Jul 15 2005, In : Journal of Biological Chemistry. 280, 28, p. 26557-26564 8 p.

Research output: Contribution to journalArticle

Talin
Myosins
Dictyostelium
Adhesion
Membranes
2003
41 Citations (Scopus)

Shared, unique and redundant functions of three members of the class I myosins (MyoA, MyoB, and MyoF) in motility and chemotaxis in Dictyostelium

Falk, D. L., Wessels, D., Jenkins, L., Pham, T., Kuhl, S., Titus, M. A. & Soll, D. R., Oct 1 2003, In : Journal of Cell Science. 116, 19, p. 3985-3999 15 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Chemotaxis
Buffers
Pseudopodia
2002
7 Citations (Scopus)

Cell motility mediates tissue size regulation in Dictyostelium

Gomer, R., Gao, T., Tang, Y., Knecht, D. & Titus, M. A., Dec 1 2002, In : Journal of Muscle Research and Cell Motility. 23, 7-8, p. 809-815 7 p.

Research output: Contribution to journalArticle

Dictyostelium
Cell Movement
Actins
Adhesion
Myosins
82 Citations (Scopus)

Requirement of a vasodilator-stimulated phosphoprotein family member for cell adhesion, the formation of filopodia, and chemotaxis in Dictyostelium

Han, Y. H., Chung, C. Y., Wessels, D., Stephens, S., Titus, M. A., Soll, D. R. & Firtel, R. A., Dec 20 2002, In : Journal of Biological Chemistry. 277, 51, p. 49877-49887 11 p.

Research output: Contribution to journalArticle

Pseudopodia
Dictyostelium
Cell adhesion
Chemotaxis
Cell Adhesion
85 Citations (Scopus)

SadA, a novel adhesion receptor in Dictyostelium

Fey, P., Stephens, S., Titus, M. A. & Chisholm, R. L., Dec 23 2002, In : Journal of Cell Biology. 159, 6, p. 1109-1119 11 p.

Research output: Contribution to journalArticle

Dictyostelium
Epidermal Growth Factor
Phenotype
Tenascin
Null Lymphocytes
2001
128 Citations (Scopus)

A role for myosin VII in dynamic cell adhesion

Tuxworth, R. I., Weber, I., Wessels, D., Addicks, G. C., Soll, D. R., Gerisch, G. & Titus, M. A., Mar 6 2001, In : Current Biology. 11, 5, p. 318-329 12 p.

Research output: Contribution to journalArticle

Cell adhesion
Myosins
myosin
cell adhesion
Cell Adhesion
8 Citations (Scopus)

Myosin I Phosphorylation Is Increased by Chemotactic Stimulation

Gliksman, N. R., Santoyo, G., Novak, K. D. & Titus, M. A., Feb 16 2001, In : Journal of Biological Chemistry. 276, 7, p. 5235-5239 5 p.

Research output: Contribution to journalArticle

Myosin Type I
Phosphorylation
Pseudopodia
Dictyostelium
Chemotactic Factors
15 Citations (Scopus)

Recruitment of a Specific Amoeboid Myosin I Isoform to the Plasma Membrane in Chemotactic Dictyostelium Cells

Senda, S., Lee, S. F., Côté, G. P. & Titus, M. A., Jan 26 2001, In : Journal of Biological Chemistry. 276, 4, p. 2898-2904 7 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Cell membranes
Protein Isoforms
Cell Membrane
2000
4 Citations (Scopus)

A potential mechanism for regulating myosin I binding to membranes in vivo

Senda, S. & Titus, M. A., Nov 3 2000, In : FEBS Letters. 484, 2, p. 125-128 4 p.

Research output: Contribution to journalArticle

Myosin Type I
Cell membranes
Cell Membrane
Membranes
Dictyostelium
58 Citations (Scopus)

Myosin VI is required for asymmetric segregation of cellular components during C. elegans spermatogenesis

Kelleher, J. F., Mandell, M. A., Moulder, G., Hill, K. L., L'Hernault, S. W., Barstead, R. & Titus, M. A., Nov 30 2000, In : Current Biology. 10, 23, p. 1489-1496 8 p.

Research output: Contribution to journalArticle

Spermatogenesis
myosin
spermatogenesis
Spermatids
spermatids
28 Citations (Scopus)

The role of unconventional myosins in Dictyostelium endocytosis

Titus, M. A., Jan 1 2000, In : Journal of Eukaryotic Microbiology. 47, 3, p. 191-196 6 p.

Research output: Contribution to journalArticle

Dictyostelium
Myosins
Endocytosis
Phagocytosis
Actins
54 Citations (Scopus)

Unconventional myosins: Anchors in the membrane traffic relay

Tuxworth, R. I. & Titus, M. A., Jan 1 2000, In : Traffic. 1, 1, p. 11-18 8 p.

Research output: Contribution to journalArticle

Myosins
Anchors
Membranes
Intracellular Membranes
Exocytosis
1999
84 Citations (Scopus)

A class VII unconventional myosin is required for phagocytosis

Titus, M. A., Nov 18 1999, In : Current Biology. 9, 22, p. 1297-1303 7 p.

Research output: Contribution to journalArticle

Myosins
myosin
phagocytosis
Phagocytosis
Actins
128 Citations (Scopus)

Myosin I contributes to the generation of resting cortical tension

Dai, J., Ting-Beall, H. P., Hochmuth, R. M., Sheetz, M. P. & Titus, M. A., Jan 1 1999, In : Biophysical Journal. 77, 2, p. 1168-1176 9 p.

Research output: Contribution to journalArticle

Myosin Type I
Myosins
Dictyostelium
Actins
Pseudopodia
1998
3 Citations (Scopus)
Biological Transport
Reunion
Myosins
Microtubules
Cell Division
21 Citations (Scopus)

Intracellular motility: How can we all work together?

Kelleher, J. F. & Titus, M. A., May 21 1998, In : Current Biology. 8, 11

Research output: Contribution to journalArticle

Microtubules
Organelles
microtubules
actin
organelles
53 Citations (Scopus)

The myosin I SH3 domain and TEDS rule phosphorylation site are required for in vivo function

Novak, K. D. & Titus, M. A., Jan 1 1998, In : Molecular Biology of the Cell. 9, 1, p. 75-88 14 p.

Research output: Contribution to journalArticle

Myosin Type I
src Homology Domains
Phosphorylation
Dictyostelium
Myosins
1997
46 Citations (Scopus)

A family of unconventional myosins from the nematode Caenorhabditis elegans

Baker, J. P. & Titus, M. A., Oct 3 1997, In : Journal of Molecular Biology. 272, 4, p. 523-535 13 p.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Myosins
Genes
Myosin Type I
Myosin Heavy Chains
55 Citations (Scopus)

Motor proteins: Myosin V - the multi-purpose transport motor

Titus, M. A., May 1 1997, In : Current Biology. 7, 5

Research output: Contribution to journalArticle

Myosin Type V
myosin
Yeast
Neurons
Proteins
66 Citations (Scopus)

Myosin I overexpression impairs cell migration

Novak, K. D. & Titus, M. A., Feb 28 1997, In : Journal of Cell Biology. 136, 3, p. 633-647 15 p.

Research output: Contribution to journalArticle

Myosin Type I
Cell Movement
Actins
Cell Surface Extensions
Phosphorylation
1996
20 Citations (Scopus)

Dictyostelium discoideum myoJ: A member of a broadly defined myosin V class or a class XI unconventional myosin?

Peterson, M. D., Urioste, A. S. & Titus, M. A., Jan 1 1996, In : Journal of Muscle Research and Cell Motility. 17, 4, p. 411-424 14 p.

Research output: Contribution to journalArticle

Myosin Type V
Dictyostelium
Myosins
Genes
Plant Genes
58 Citations (Scopus)

Examination of the endosomal and lysosomal pathways in Dictyostelium discoideum myosin I mutants

Temesvari, L. A., Bush, J. M., Peterson, M. D., Novak, K. D., Titus, M. A. & Cardelli, J. A., Mar 1 1996, In : Journal of Cell Science. 109, 3, p. 663-673 11 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Mannosidases
Myosins
Vacuoles
1995
64 Citations (Scopus)

A Dictyostelium myosin I plays a crucial role in regulating the frequency of pseudopods formed on the substratum

Wessels, D., Titus, M. & Soll, D. R., Dec 1 1995, In : Cell Motility and the Cytoskeleton. 33, 1, p. 64-79 16 p.

Research output: Contribution to journalArticle

Myosin Type I
Pseudopodia
Dictyostelium
3 Citations (Scopus)

Determinants of motor polarity in the kinesin proteins

Endow, S. A., Cole, D., Cooke, R., Titus, M. & Pollack, G., Jan 1 1995, In : Biophysical journal. 68, 4 SUPPL.

Research output: Contribution to journalArticle

Kinesin
Proteins
Microtubule Proteins
Microtubules
158 Citations (Scopus)

Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis

Novak, K. D., Peterson, M. D., Reedy, M. C. & Titus, M. A., Dec 1 1995, In : Journal of Cell Biology. 131, 5, p. 1205-1221 17 p.

Research output: Contribution to journalArticle

Myosin Type I
Pinocytosis
Dictyostelium
Actins
Suspensions
45 Citations (Scopus)

Molecular genetic analysis of myoC, a Dictyostelium myosin I

Peterson, M. D., Novak, K. D., Reedy, M. C., Ruman, J. I. & Titus, M. A., Jan 1 1995, In : Journal of Cell Science. 108, 3, p. 1093-1103 11 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Myosins
Molecular Biology
Actins
17 Citations (Scopus)

Molecular genetic analysis of myoF, a new Dictyostelium myosin I gene

Titus, M. A., Novak, K. D., Hanes, G. P., Urioste, A. S., Chisholm, R., Ostap, M., Cooke, R., Gillespie, P. & Block, S., Jan 1 1995, In : Biophysical Journal. 68, 4 SUPPL.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Myosins
Molecular Biology
Actins