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Research Output 1982 2018

2018

Developing Evolutionary Cell Biology

Titus, M. A. & Goodson, H. V., Nov 19 2018, In : Developmental Cell. 47, 4, p. 395-396 2 p.

Research output: Contribution to journalShort survey

Cytology
Cell Biology
Animals
3 Citations (Scopus)
Myosins
Actins
Fungi
Actin Cytoskeleton
Chemical activation
3 Citations (Scopus)
Myosins
Actins
Fungi
Actin Cytoskeleton
Chemical activation
3 Citations (Scopus)

Myosin-driven intracellular transport

Titus, M. A., Mar 1 2018, In : Cold Spring Harbor Perspectives in Biology. 10, 3, a021972.

Research output: Contribution to journalArticle

Myosins
Actins
Fungi
Actin Cytoskeleton
Chemical activation
2017

An evolutionary perspective on cell migration: Digging for the roots of amoeboid motility

Titus, M. A. & Goodson, H. V., Jun 1 2017, In : Journal of Cell Biology. 216, 6, p. 1509-1511 3 p.

Research output: Contribution to journalComment/debate

Pseudopodia
Cell Movement
Actins
Genome
2 Citations (Scopus)

Growing, splitting and stacking myosin II filaments

Titus, M. A., Jan 31 2017, In : Nature Cell Biology. 19, 2, p. 77-79 3 p.

Research output: Contribution to journalArticle

Myosin Type II
Stress Fibers
Actin Cytoskeleton
Actins
8 Citations (Scopus)

Myosin 7 and its adaptors link cadherins to actin

Yu, I. M., Planelles-Herrero, V. J., Sourigues, Y., Moussaoui, D., Sirkia, H., Kikuti, C., Stroebel, D., Titus, M. A. & Houdusse, A., Jun 29 2017, In : Nature communications. 8, 15864.

Research output: Contribution to journalArticle

Open Access
Stereocilia
myosins
Cadherins
Myosins
Actins
2016
15 Citations (Scopus)

Coordinated recruitment of spir actin nucleators and myosin V motors to rab11 vesicle membranes

Pylypenko, O., Welz, T., Tittel, J., Kollmar, M., Chardon, F., Malherbe, G., Weiss, S., Michel, C. I. L., Samol-Wolf, A., Grasskamp, A. T., Hume, A., Goud, B., Baron, B., England, P., Titus, M. A., Schwille, P., Weidemann, T., Houdusse, A. & Kerkhoff, E., Sep 13 2016, In : eLife. 5, September, e17523.

Research output: Contribution to journalArticle

Myosin Type V
Actins
Membranes
Myosins
rab GTP-Binding Proteins
9 Citations (Scopus)

Myosin MyTH4-FERM structures highlight important principles of convergent evolution

Planelles-Herrero, V. J., Blanc, F., Sirigu, S., Sirkia, H., Clause, J., Sourigues, Y., Johnsrud, D. O., Amigues, B., Cecchini, M., Gilbert, S. P., Houdusse, A. & Titus, M. A., May 24 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. E2906-E2915

Research output: Contribution to journalArticle

Myosins
Microtubules
Tail
Binding Sites
Pseudopodia
6 Citations (Scopus)

MyTH4-FERM myosins have an ancient and conserved role in filopod formation

Petersen, K. J., Goodson, H. V., Arthur, A. L., Luxton, G. W. G., Houdusse, A., Titus, M. A. & Devreotes, P. N., Dec 13 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 50, p. E8059-E8068

Research output: Contribution to journalArticle

Myosins
Pseudopodia
Amoebozoa
Null Lymphocytes
Amoeba
7 Citations (Scopus)

Selective localization of myosin-I proteins in macropinosomes and actin waves

Brzeska, H., Koech, H., Pridham, K. J., Korn, E. D. & Titus, M. A., Feb 1 2016, In : Cytoskeleton. 73, 2, p. 68-82 15 p.

Research output: Contribution to journalArticle

Myosin Type I
Actins
Myosins
Proteins
Dictyostelium
2014
12 Citations (Scopus)

The association of myosin IB with actin waves in dictyostelium requires both the plasma membrane-binding site and actin-binding region in the myosin tail

Brzeska, H., Pridham, K., Chery, G., Titus, M. A. & Korn, E. D., Apr 18 2014, In : PloS one. 9, 4, e94306.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Cell membranes
Myosins
myosin
2013

Myosin motors

Titus, M. A. & Larson, R. E., Feb 15 2013, Encyclopedia of Biological Chemistry: Second Edition. Elsevier Inc., p. 778-781 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Myosins
Muscle Contraction
Muscle
Cytoplasmic Streaming
Myosin Type V
39 Citations (Scopus)

Structural basis of myosin v Rab GTPase-dependent cargo recognition

Pylypenko, O., Attanda, W., Gauquelin, C., Lahmani, M., Coulibaly, D., Baron, B., Hoos, S., Titus, M. A., England, P. & Houdusse, A. M., Dec 17 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 51, p. 20443-20448 6 p.

Research output: Contribution to journalArticle

rab GTP-Binding Proteins
Myosins
Protein Isoforms
Melanosomes
Membranes
2012
5 Citations (Scopus)

Allosteric communication in Dictyostelium myosin II

Guhathakurta, P., Prochniewicz-Nakayama, E., Muretta, J. M., Titus, M. A. & Thomas, D. D., Oct 1 2012, In : Journal of Muscle Research and Cell Motility. 33, 5, p. 305-312 8 p.

Research output: Contribution to journalArticle

Myosin Type II
Dictyostelium
Myosins
Actins
Adenosine Diphosphate
8 Citations (Scopus)

Molecular basis of dynamic relocalization of Dictyostelium Myosin IB

Brzeska, H., Guag, J., Preston, G. M., Titus, M. A. & Korn, E. D., Apr 27 2012, In : Journal of Biological Chemistry. 287, 18, p. 14923-14936 14 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Molecular Dynamics Simulation
Cell membranes
Myosins
2011
10 Citations (Scopus)

Characterization of a myosin VII MyTH/FERM domain

Moen, R. J., Johnsrud, D. O., Thomas, D. D. & Titus, M. A., Oct 14 2011, In : Journal of Molecular Biology. 413, 1, p. 17-23 7 p.

Research output: Contribution to journalArticle

Myosins
Microtubules
Dictyostelium
Deafness
Cytoskeleton

Cytoskeletons by the sea

Titus, M. A., Mar 1 2011, In : EMBO Reports. 12, 3, p. 185-187 3 p.

Research output: Contribution to journalArticle

Cytoskeletal Proteins
Cytoskeleton
Oceans and Seas
Coastal zones
Molecules
15 Citations (Scopus)

Structural and functional impact of site-directed methionine oxidation in myosin

Klein, J. C., Moen, R. J., Smith, E. A., Titus, M. A. & Thomas, D. D., Nov 29 2011, In : Biochemistry. 50, 47, p. 10318-10327 10 p.

Research output: Contribution to journalArticle

Myosins
Methionine
Actins
Oxidation
Dictyostelium
39 Citations (Scopus)

Structural kinetics of myosin by transient time-resolved FRET

Nesmelov, Y. E., Agafonov, R. V., Negrashov, I. V., Blakely, S. E., Titus, M. A. & Thomas, D. D., Feb 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 5, p. 1891-1896 6 p.

Research output: Contribution to journalArticle

Myosins
Molecular Motor Proteins
Adenosine Triphosphate
Fluorescence
Stroke
2010
16 Citations (Scopus)

An unconventional myosin required for cell polarization and chemotaxis

Breshears, L. M., Wessels, D., Soll, D. R. & Titus, M. A., Apr 13 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 15, p. 6918-6923 6 p.

Research output: Contribution to journalArticle

Chemotaxis
Myosins
Actins
Stereocilia
Cell Polarity
2009
4 Citations (Scopus)

Motors: Unleashing Mitochondria

Titus, M. A., Dec 15 2009, In : Current Biology. 19, 23

Research output: Contribution to journalShort survey

Mitochondria
mitochondria
Myosins
myosin
actin
47 Citations (Scopus)

Structural dynamics of the myosin relay helix by time-resolved EPR and FRET

Agafonov, R. V., Negrashov, I. V., Tkachev, Y. V., Blakely, S. E., Titus, M. A., Thomas, D. D. & Nesmelov, Y. E., Dec 22 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 51, p. 21625-21630 6 p.

Research output: Contribution to journalArticle

Myosins
Stroke
Adenosine Diphosphate
Nucleotides
Adenosine Triphosphate
17 Citations (Scopus)

The Dictyostelium type V myosin MyoJ is responsible for the cortical association and motility of contractile vacuole membranes

Jung, G., Titus, M. A. & Hammer, J. A., Aug 24 2009, In : Journal of Cell Biology. 186, 4, p. 555-570 16 p.

Research output: Contribution to journalArticle

Myosin Type V
Dictyostelium
Vacuoles
Membranes
Null Lymphocytes
2008
36 Citations (Scopus)

Actin-binding cleft closure in myosin II probed by site-directed spin labeling and pulsed EPR

Klein, J. C., Burr, A. R., Svensson, B., Kennedy, D. J., Allingham, J., Titus, M. A., Rayment, I. & Thomas, D. D., Sep 2 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 35, p. 12867-12872 6 p.

Research output: Contribution to journalArticle

Myosin Type II
Electron Spin Resonance Spectroscopy
Actins
Cysteine
Nucleotides
23 Citations (Scopus)
Spin Labels
Myosins
Muscles
Dictyostelium
Electron Spin Resonance Spectroscopy
2007
1 Citation (Scopus)

Motor Proteins: Tightening Your Belt with Myosin VI

Breshears, L. M. & Titus, M. A., Nov 6 2007, In : Current Biology. 17, 21

Research output: Contribution to journalShort survey

Vinculin
Adherens Junctions
cadherins
Cadherins
myosin
10 Citations (Scopus)

Talin influences the dynamics of the myosin VII-membrane interaction

Galdeen, S. A., Stephens, S., Thomas, D. D. & Titus, M. A., Oct 1 2007, In : Molecular Biology of the Cell. 18, 10, p. 4074-4084 11 p.

Research output: Contribution to journalArticle

Talin
Myosins
Dictyostelium
Membranes
Green Fluorescent Proteins
8 Citations (Scopus)

The SH3 domain of a M7 interacts with its C-terminal proline-rich region

Wang, Q., Deloia, M. A., Kang, Y., Litchke, C., Zhang, N., Titus, M. A. & Walters, K. J., Feb 1 2007, In : Protein Science. 16, 2, p. 189-196 8 p.

Research output: Contribution to journalArticle

src Homology Domains
Proline
Myosins
Proteins
Myosin Type I
2006
1 Citation (Scopus)

Myosin I and Actin Dynamics: The Frogs Weigh In

Titus, M. A., Nov 1 2006, In : Developmental Cell. 11, 5, p. 594-595 2 p.

Research output: Contribution to journalShort survey

Myosin Type I
Anura
Actins
Xenopus
Endocytosis
18 Citations (Scopus)

Structural dynamics of the actin-myosin interface by site-directed spectroscopy

Korman, V. L., Anderson, S. E. B., Prochniewicz-Nakayama, E., Titus, M. A. & Thomas, D. D., Mar 10 2006, In : Journal of Molecular Biology. 356, 5, p. 1107-1117 11 p.

Research output: Contribution to journalArticle

Myosins
Actins
Spectrum Analysis
Actomyosin
Fluorescence
2005
1 Citation (Scopus)
Myosins
Talin
Dictyostelium
Tail
Phenotype

Discussion

Lane, D., Nelson, W. J., Sheetz, M., Drubin, D., Firtel, R., Hong, W., Borisy, W. G., Braga, V., Kaibuchi, K., Titus, M. A., Chang, F., Lane, B., Humphries, M., Vallee, R., Peter, M. & Gu, F., Dec 1 2005, Signalling Networks in Cell Shape and Motility. p. 168-177 10 p. (Novartis Foundation Symposium; vol. 269).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Discussion

Sheetz, M., Firtel, R., Titus, M. A., Borisy, G., Alberts, A., Peter, M., Harden, N. & Nelson, W. J., Dec 1 2005, Signalling Networks in Cell Shape and Motility. Vol. 269. p. 87-91 5 p. (Novartis Foundation Symposium; vol. 269).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Discussion

Drubin, D., Titus, M. A., Luca, F., Borisy, G., Nelson, W. J., Alberts, A., Cai, M., Sheetz, M., Harden, N., Vallee, R., Firtel, R., Takenawa, T. & Chang, F., Dec 1 2005, Signalling Networks in Cell Shape and Motility. p. 24-29 6 p. (Novartis Foundation Symposium; vol. 269).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Discussion

Borisy, G., Braga, V., Chang, F., Harden, N., Humphries, M., Kaibuchi, K., Lim, L., Nelson, W. J., Sheetz, M., Titus, M. A. & Yap, A., Dec 1 2005, Signalling Networks in Cell Shape and Motility. Vol. 269. p. 155-158 4 p. (Novartis Foundation Symposium; vol. 269).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Evolution: A treasure trove of motors

Titus, M. A., Aug 25 2005, In : Nature. 436, 7054, p. 1097-1099 3 p.

Research output: Contribution to journalShort survey

Myosins
Eukaryota
Sequence Analysis
Proteins
24 Citations (Scopus)

Identification of a myosin VII-talin complex

Tuxworth, R. I., Stephens, S., Ryan, Z. C. & Titus, M. A., Jul 15 2005, In : Journal of Biological Chemistry. 280, 28, p. 26557-26564 8 p.

Research output: Contribution to journalArticle

Talin
Myosins
Dictyostelium
Adhesion
Membranes
2004

Cell structure and dynamics

Cooper, J. A. & Titus, M. A., Feb 1 2004, In : Current Opinion in Cell Biology. 16, 1, p. 1-3 3 p.

Research output: Contribution to journalEditorial

4 Citations (Scopus)

Myosins meet microtubules

Titus, M. A., Sep 16 2004, In : Nature. 431, 7006, p. 252-253 2 p.

Research output: Contribution to journalShort survey

Cellular Structures
Myosins
Microtubules
Cell Division
2003
9 Citations (Scopus)

Caveat experimentor - Is your myosin really inhibited?

Titus, M. A., Feb 1 2003, In : Nature Cell Biology. 5, 2, 1 p.

Research output: Contribution to journalComment/debate

Diacetyl
Enzyme Inhibitors
Myosins
Protein Isoforms
Skeletal Muscle
41 Citations (Scopus)

Shared, unique and redundant functions of three members of the class I myosins (MyoA, MyoB, and MyoF) in motility and chemotaxis in Dictyostelium

Falk, D. L., Wessels, D., Jenkins, L., Pham, T., Kuhl, S., Titus, M. A. & Soll, D. R., Oct 1 2003, In : Journal of Cell Science. 116, 19, p. 3985-3999 15 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Chemotaxis
Buffers
Pseudopodia
2002
7 Citations (Scopus)

Cell motility mediates tissue size regulation in Dictyostelium

Gomer, R., Gao, T., Tang, Y., Knecht, D. & Titus, M. A., Dec 1 2002, In : Journal of Muscle Research and Cell Motility. 23, 7-8, p. 809-815 7 p.

Research output: Contribution to journalArticle

Dictyostelium
Cell Movement
Actins
Adhesion
Myosins
82 Citations (Scopus)

Requirement of a vasodilator-stimulated phosphoprotein family member for cell adhesion, the formation of filopodia, and chemotaxis in Dictyostelium

Han, Y. H., Chung, C. Y., Wessels, D., Stephens, S., Titus, M. A., Soll, D. R. & Firtel, R. A., Dec 20 2002, In : Journal of Biological Chemistry. 277, 51, p. 49877-49887 11 p.

Research output: Contribution to journalArticle

Pseudopodia
Dictyostelium
Cell adhesion
Chemotaxis
Cell Adhesion
84 Citations (Scopus)

SadA, a novel adhesion receptor in Dictyostelium

Fey, P., Stephens, S., Titus, M. A. & Chisholm, R. L., Dec 23 2002, In : Journal of Cell Biology. 159, 6, p. 1109-1119 11 p.

Research output: Contribution to journalArticle

Dictyostelium
Epidermal Growth Factor
Phenotype
Tenascin
Null Lymphocytes
2001
128 Citations (Scopus)

A role for myosin VII in dynamic cell adhesion

Tuxworth, R. I., Weber, I., Wessels, D., Addicks, G. C., Soll, D. R., Gerisch, G. & Titus, M. A., Mar 6 2001, In : Current Biology. 11, 5, p. 318-329 12 p.

Research output: Contribution to journalArticle

Cell adhesion
Myosins
myosin
cell adhesion
Cell Adhesion
55 Citations (Scopus)

Myosin-I nomenclature

Gillespie, P. G., Albanesi, J. P., Bähler, M., Bement, W. M., Berg, J. S., Burgess, D. R., Burnside, B., Cheney, R. E., Corey, D. P., Coudrier, E., De Lanerolle, P., Hammer, J. A., Hasson, T., Holt, J. R., Hudspeth, A. J., Ikebe, M., Kendrick-Jones, J., Korn, E. D., Li, R., Mercer, J. A. & 8 othersMilligan, R. A., Mooseker, M. S., Michael Ostap, E., Petit, C., Pollard, T. D., Sellers, J. R., Soldati, T. & Titus, M. A., Nov 26 2001, In : Journal of Cell Biology. 155, 5, p. 703-704 2 p.

Research output: Contribution to journalShort survey

Myosin Type I
Terminology
Names
Human Genome
Vertebrates
8 Citations (Scopus)

Myosin I Phosphorylation Is Increased by Chemotactic Stimulation

Gliksman, N. R., Santoyo, G., Novak, K. D. & Titus, M. A., Feb 16 2001, In : Journal of Biological Chemistry. 276, 7, p. 5235-5239 5 p.

Research output: Contribution to journalArticle

Myosin Type I
Phosphorylation
Pseudopodia
Dictyostelium
Chemotactic Factors
15 Citations (Scopus)

Recruitment of a Specific Amoeboid Myosin I Isoform to the Plasma Membrane in Chemotactic Dictyostelium Cells

Senda, S., Lee, S. F., Côté, G. P. & Titus, M. A., Jan 26 2001, In : Journal of Biological Chemistry. 276, 4, p. 2898-2904 7 p.

Research output: Contribution to journalArticle

Myosin Type I
Dictyostelium
Cell membranes
Protein Isoforms
Cell Membrane