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Research Output 2006 2019

2019

A review of avelumab in locally advanced and metastatic bladder cancer

Rao, A. & Patel, M. R., Feb 8 2019, In : Therapeutic Advances in Urology. 11, p. 1756287218823485

Research output: Contribution to journalReview article

Urinary Bladder Neoplasms
United States Food and Drug Administration
Cell Death
Carcinoma
Drug Approval

Immune Checkpoint Inhibitors in ROS1-Rearranged Non–Small Cell Lung Cancer: A Report of Two Cases

Jain, A., Fujioka, N. & Patel, M. R., Aug 1 2019, In : Journal of Thoracic Oncology. 14, 8, p. e165-e167

Research output: Contribution to journalLetter

Non-Small Cell Lung Carcinoma

Impact of Immune Therapy in Elderly Patients with Non-Small Cell Lung Cancer (NSCLC): A Systematic Review

Kumar, M., Patel, M. R., Smith, A. & Bakker, C. J., Apr 2019.

Research output: Contribution to conferencePoster

Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer

De, A., Jacobson, B. A., Peterson, M. S., Stelzner, M. E., Jay-Dixon, J., Kratzke, M. G., Patel, M. R., Bitterman, P. B. & Kratzke, R. A., May 1 2019, In : Cancer gene therapy. 26, 5-6, p. 157-165 9 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4F
Non-Small Cell Lung Carcinoma
Genome
Growth
gemcitabine
2 Citations (Scopus)

JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models

Patel, M. R., Dash, A., Jacobson, B. A., Ji, Y., Baumann, D., Ismail, K. & Kratzke, R. A., Nov 1 2019, In : Cancer gene therapy. 26, 11-12, p. 411-418 8 p.

Research output: Contribution to journalArticle

Oncolytic Virotherapy
Vesicular Stomatitis
Non-Small Cell Lung Carcinoma
Interferons
Viruses
2018
2 Citations (Scopus)

4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma

De, A., Jacobson, B. A., Peterson, M. S., Jay-Dixon, J., Kratzke, M. G., Sadiq, A. A., Patel, M. R. & Kratzke, R. A., Apr 1 2018, In : Investigational New Drugs. 36, 2, p. 217-229 13 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4F
Genome
gemcitabine
Pemetrexed
Osteopontin
15 Citations (Scopus)

A first-in-human phase I study of subcutaneous outpatient recombinant human IL15 (rhIL15) in adults with advanced solid tumors

Miller, J. S., Morishima, C., McNeel, D. G., Patel, M. R., Kohrt, H. E. K., Thompson, J. A., Sondel, P. M., Wakelee, H. A., Disis, M. L., Kaiser, J. C., Cheever, M. A., Streicher, H., Creekmore, S. P., Waldmann, T. A. & Conlon, K. C., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1525-1535 11 p.

Research output: Contribution to journalArticle

Interleukin-15
Outpatients
Neoplasms
T-Lymphocytes
Troponin
40 Citations (Scopus)

ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial

Wrangle, J. M., Velcheti, V., Patel, M. R., Garrett-Mayer, E., Hill, E. G., Ravenel, J. G., Miller, J. S., Farhad, M., Anderton, K., Lindsey, K., Taffaro-Neskey, M., Sherman, C., Suriano, S., Swiderska-Syn, M., Sion, A., Harris, J., Edwards, A. R., Rytlewski, J. A., Sanders, C. M., Yusko, E. C. & 9 others, Robinson, M. D., Krieg, C., Redmond, W. L., Egan, J. O., Rhode, P. R., Jeng, E. K., Rock, A. D., Wong, H. C. & Rubinstein, M. P., May 1 2018, In : The Lancet Oncology. 19, 5, p. 694-704 11 p.

Research output: Contribution to journalArticle

Interleukin-15
Non-Small Cell Lung Carcinoma
Immunotherapy
ALT-803
nivolumab

Immunotherapy for thoracic oncology gone viral

Patel, M. R., Apr 1 2018, In : Immunotherapy. 10, 5, p. 383-390 8 p.

Research output: Contribution to journalReview article

Oncolytic Viruses
Immunotherapy
Thorax
Lung Neoplasms
Standard of Care
2017
4 Citations (Scopus)

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma

Jacobson, B. A., Sadiq, A. A., Tang, S., Jay-Dixon, J., Patel, M. R., Drees, J., Sorenson, B. S., Russell, S. J. & Kratzke, R. A., Jan 1 2017, In : Oncotarget. 8, 38, p. 63096-63109 14 p.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Measles virus
Virus Diseases
Mesothelioma
Repressor Proteins
1 Citation (Scopus)

Viroimmunotherapy of thoracic cancers

Dash, A. S. & Patel, M. R., Mar 1 2017, In : Biomedicines. 5, 1, 2.

Research output: Contribution to journalReview article

Open Access
Viruses
Thorax
Cells
Oncolytic Viruses
Neoplasms
2016
28 Citations (Scopus)
Cardiac Tamponade
Pleural Effusion
Therapeutics
Pericardiocentesis
Pericardial Effusion
2015
14 Citations (Scopus)

Antisense oligonucleotide targeting eukaryotic translation initiation factor 4E reduces growth and enhances chemosensitivity of non-small-cell lung cancer cells

Thumma, S. C., Jacobson, B. A., Patel, M. R., Konicek, B. W., Franklin, M. J., Jay-Dixon, J., Sadiq, A., De, A., Graff, J. R. & Kratzke, R. A., Aug 18 2015, In : Cancer gene therapy. 22, 8, p. 396-401 6 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factors
Antisense Oligonucleotides
Non-Small Cell Lung Carcinoma
Growth
5 Citations (Scopus)

Endometrial metastasis of lung adenocarcinoma: A report of two cases

Ahmad, Z., Raza, A. & Patel, M. R., May 18 2015, In : American Journal of Case Reports. 16, p. 296-299 4 p.

Research output: Contribution to journalArticle

Neoplasm Metastasis
Lung Neoplasms
Biopsy
Uterus
Uterine Neoplasms
1 Citation (Scopus)

Genetic Engineering of Oncolytic Viruses for Cancer Therapy

Patel, M. R. & Kratzke, R. A., Jan 1 2015, Translating Gene Therapy to the Clinic: Techniques and Approaches. Elsevier Inc., p. 261-279 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oncolytic Virotherapy
Genetic engineering
Genetic Engineering
Viruses
Oncolytic Viruses
1 Citation (Scopus)

Targeting topoisomerase II activity in NSCLC with 9-aminoacridine derivatives

Ferguson, D. M., Jacobson, B. A., Jay-Dixon, J., Patel, M. R., Kratzke, R. A. & Raza, A., Jan 1 2015, In : Anticancer Research. 35, 10, p. 5211-5218 8 p.

Research output: Contribution to journalArticle

Aminacrine
Acridines
Type II DNA Topoisomerase
Non-Small Cell Lung Carcinoma
Poisons
13 Citations (Scopus)

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

Jacobson, B. A., Chen, E. Z., Tang, S., Belgum, H. S., McCauley, J. A., Evenson, K. A., Etchison, R. G., Jay-Dixon, J., Patel, M. R., Raza, A., Saluja, A. K., D’Cunha, J. & Kratzke, R. A., Jan 1 2015, In : Genes and Cancer. 6, 3-4, p. 144-152 9 p.

Research output: Contribution to journalArticle

Mesothelioma
Prodrugs
Heterografts
Growth
Cell Survival
32 Citations (Scopus)

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Patel, M. R., Jacobson, B. A., Ji, Y., Drees, J., Tang, S., Xiong, K., Wang, H., Prigge, J. E., Dash, A. S., Kratzke, A. K., Mesev, E., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Jan 1 2015, In : Oncotarget. 6, 32, p. 33165-33177 13 p.

Research output: Contribution to journalArticle

Vesicular Stomatitis
Non-Small Cell Lung Carcinoma
Interferons
Viruses
Neoplasms
2014
1 Citation (Scopus)

An absolute obstacle: Cardiac metastasis of synovial sarcoma

Vakil, K. P., Raza, A., Zakharova, M. Y., Madlon-Kay, R., Skubitz, K. M. & Patel, M. R., Jan 1 2014, In : American Journal of Medicine. 127, 5, p. 390-392 3 p.

Research output: Contribution to journalComment/debate

Neoplasm Drug Resistance
Antineoplastic Combined Chemotherapy Protocols
Treatment Refusal
Vascular Neoplasms
Synovial Sarcoma
10 Citations (Scopus)

Measles vaccine strains for virotherapy of non-small-cell lung carcinoma

Patel, M. R., Jacobson, B. A., Belgum, H., Raza, A., Sadiq, A., Drees, J., Wang, H., Jay-Dixon, J., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Jan 1 2014, In : Journal of Thoracic Oncology. 9, 8, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

Measles Vaccine
Measles virus
Non-Small Cell Lung Carcinoma
Carcinoembryonic Antigen
Virus Diseases
10 Citations (Scopus)

Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells

Chen, E. Z., Jacobson, B. A., Patel, M. R., Okon, A. M., Li, S., Xiong, K., Vaidya, A. J., Bitterman, P. B., Wagner, C. R. & Kratzke, R. A., Jan 1 2014, In : Investigational New Drugs. 32, 4, p. 598-603 6 p.

Research output: Contribution to journalArticle

Mesothelioma
Protein Biosynthesis
Pemetrexed
Prodrugs
Messenger RNA
2013
60 Citations (Scopus)

Oncolytic virus therapy for cancer: The first wave of translational clinical trials

Patel, M. R. & Kratzke, R. A., Jan 1 2013, In : Translational Research. 161, 4, p. 355-364 10 p.

Research output: Contribution to journalReview article

Oncolytic Virotherapy
Viruses
Clinical Trials
Oncolytic Viruses
Neoplasms
9 Citations (Scopus)
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Eukaryotic Initiation Factor-4F
Phosphorylation
20 Citations (Scopus)

Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide

Jacobson, B. A., Thumma, S. C., Jay-Dixon, J., Patel, M. R., Dubear Kroening, K., Kratzke, M. G., Etchison, R. G., Konicek, B. W., Graff, J. R. & Kratzke, R. A., Nov 18 2013, In : PloS one. 8, 11, e81669.

Research output: Contribution to journalArticle

gemcitabine
Pemetrexed
mesothelioma
Antisense Oligonucleotides
Mesothelioma
2012
11 Citations (Scopus)
Topoisomerase II Inhibitors
Acridines
Mesothelioma
Cell Proliferation
Apoptosis
11 Citations (Scopus)

Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation

Patel, M. R., Sadiq, A. A., Jay-Dixon, J., Jirakulaporn, T., Jacobson, B. A., Farassati, F., Bitterman, P. B. & Kratzke, R. A., Feb 1 2012, In : International Journal of Oncology. 40, 2, p. 577-582 6 p.

Research output: Contribution to journalArticle

JNK Mitogen-Activated Protein Kinases
Non-Small Cell Lung Carcinoma
Translational Peptide Chain Initiation
Mesothelioma
Intercellular Signaling Peptides and Proteins
2011
8 Citations (Scopus)

Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues

Kodali, D., Rawal, A., Ninan, M. J., Patel, M. R., Mesa, H., Knapp, D., Schnitzer, B., Kratzke, R. A. & Gupta, P., Mar 1 2011, In : Archives of Pathology and Laboratory Medicine. 135, 3, p. 365-371 7 p.

Research output: Contribution to journalArticle

Eukaryotic Initiation Factor-4E
Eukaryotic Initiation Factors
B-Cell Lymphoma
Lymphoid Tissue
Lymphoma
2010
23 Citations (Scopus)

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II

Sadiq, A. A., Patel, M. R., Jacobson, B. A., Escobedo, M., Ellis, K., Oppegard, L. M., Hiasa, H. & Kratzke, R. A., Jan 1 2010, In : Investigational New Drugs. 28, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

Topoisomerase II Inhibitors
Type II DNA Topoisomerase
Cell Line
Inhibitory Concentration 50
Poisons
2009
20 Citations (Scopus)

Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma

Jacobson, B. A., De, A., Kratzke, M. G., Patel, M. R., Jay-Dixon, J., Whitson, B. A., Sadiq, A. A., Bitterman, P. B., Polunovsky, V. A. & Kratzke, R. A., Aug 4 2009, In : British Journal of Cancer. 101, 3, p. 424-431 8 p.

Research output: Contribution to journalArticle

Mesothelioma
Insulin-Like Growth Factor I
Protein Biosynthesis
Repressor Proteins
Cell Line
2008
236 Citations (Scopus)

Vitamin D intake to attain a desired serum 25-hydroxyvitamin D concentration

Aloia, J. F., Patel, M., DiMaano, R., Li-Ng, M., Talwar, S. A., Mikhail, M., Pollack, S. & Yeh, J. K., Jun 1 2008, In : American Journal of Clinical Nutrition. 87, 6, p. 1952-1958 7 p.

Research output: Contribution to journalArticle

Vitamin D
Cholecalciferol
Serum
Hypercalciuria
Nutrition Surveys
2007
19 Citations (Scopus)

Ras pathway activation in malignant mesothelioma

Patel, M. R., Jacobson, B. A., De, A., Frizelle, S. P., Janne, P., Thumma, S. C., Whitson, B. A., Farassati, F. & Kratzke, R. A., Sep 1 2007, In : Journal of Thoracic Oncology. 2, 9, p. 789-795 7 p.

Research output: Contribution to journalArticle

Mesothelioma
Phosphotransferases
Cell Line
JNK Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinase 9
2006
18 Citations (Scopus)

Effects of Insulin-Like Growth Factor-1 Receptor Inhibition in Mesothelioma

Whitson, B. A., Jacobson, B. A., Frizelle, S., Patel, M. R., Yee, D., Maddaus, M. A. & Kratzke, R. A., Sep 1 2006, In : Annals of Thoracic Surgery. 82, 3, p. 996-1002 7 p.

Research output: Contribution to journalArticle

Somatomedin Receptors
Mesothelioma
Phosphorylation
Cell Culture Techniques
Cell Line