20062024

Research output per year

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Research Output

2020

Repression of oncogenic cap-mediated translation by 4Ei-10 diminishes proliferation, enhances chemosensitivity and alters expression of malignancy-related proteins in mesothelioma

Ahmad, Z., Jacobson, B. A., McDonald, M. W., Vattendahl Vidal, N., Vattendahl Vidal, G., Chen, S., Dillenburg, M., Okon, A. M., Patel, M. R., Wagner, C. R. & Kratzke, R. A., Feb 1 2020, In : Cancer chemotherapy and pharmacology. 85, 2, p. 425-432 8 p.

Research output: Contribution to journalArticle

2019

A review of avelumab in locally advanced and metastatic bladder cancer

Rao, A. & Patel, M. R., Feb 8 2019, In : Therapeutic Advances in Urology. 11, p. 1756287218823485

Research output: Contribution to journalReview article

2 Scopus citations

Impact of Immune Therapy in Elderly Patients with Non-Small Cell Lung Cancer (NSCLC): A Systematic Review

Kumar, M., Patel, M. R., Smith, A. & Bakker, C. J., Apr 2019.

Research output: Contribution to conferencePoster

Inhibition of oncogenic cap-dependent translation by 4EGI-1 reduces growth, enhances chemosensitivity and alters genome-wide translation in non-small cell lung cancer

De, A., Jacobson, B. A., Peterson, M. S., Stelzner, M. E., Jay-Dixon, J., Kratzke, M. G., Patel, M. R., Bitterman, P. B. & Kratzke, R. A., May 1 2019, In : Cancer gene therapy. 26, 5-6, p. 157-165 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

JAK/STAT inhibition with ruxolitinib enhances oncolytic virotherapy in non-small cell lung cancer models

Patel, M. R., Dash, A., Jacobson, B. A., Ji, Y., Baumann, D., Ismail, K. & Kratzke, R. A., Nov 1 2019, In : Cancer gene therapy. 26, 11-12, p. 411-418 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2018

4EGI-1 represses cap-dependent translation and regulates genome-wide translation in malignant pleural mesothelioma

De, A., Jacobson, B. A., Peterson, M. S., Jay-Dixon, J., Kratzke, M. G., Sadiq, A. A., Patel, M. R. & Kratzke, R. A., Apr 1 2018, In : Investigational New Drugs. 36, 2, p. 217-229 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

A first-in-human phase I study of subcutaneous outpatient recombinant human IL15 (rhIL15) in adults with advanced solid tumors

Miller, J. S., Morishima, C., McNeel, D. G., Patel, M. R., Kohrt, H. E. K., Thompson, J. A., Sondel, P. M., Wakelee, H. A., Disis, M. L., Kaiser, J. C., Cheever, M. A., Streicher, H., Creekmore, S. P., Waldmann, T. A. & Conlon, K. C., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1525-1535 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial

Wrangle, J. M., Velcheti, V., Patel, M. R., Garrett-Mayer, E., Hill, E. G., Ravenel, J. G., Miller, J. S., Farhad, M., Anderton, K., Lindsey, K., Taffaro-Neskey, M., Sherman, C., Suriano, S., Swiderska-Syn, M., Sion, A., Harris, J., Edwards, A. R., Rytlewski, J. A., Sanders, C. M., Yusko, E. C. & 9 others, Robinson, M. D., Krieg, C., Redmond, W. L., Egan, J. O., Rhode, P. R., Jeng, E. K., Rock, A. D., Wong, H. C. & Rubinstein, M. P., May 2018, In : The Lancet Oncology. 19, 5, p. 694-704 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Immunotherapy for thoracic oncology gone viral

Patel, M. R., Apr 2018, In : Immunotherapy. 10, 5, p. 383-390 8 p.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations
2017

Cap-dependent translational control of oncolytic measles virus infection in malignant mesothelioma

Jacobson, B. A., Sadiq, A. A., Tang, S., Jay-Dixon, J., Patel, M. R., Drees, J., Sorenson, B. S., Russell, S. J. & Kratzke, R. A., Jan 1 2017, In : Oncotarget. 8, 38, p. 63096-63109 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Viroimmunotherapy of thoracic cancers

Dash, A. S. & Patel, M. R., Mar 1 2017, In : Biomedicines. 5, 1, 2.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2016
31 Scopus citations
2015

Antisense oligonucleotide targeting eukaryotic translation initiation factor 4E reduces growth and enhances chemosensitivity of non-small-cell lung cancer cells

Thumma, S. C., Jacobson, B. A., Patel, M. R., Konicek, B. W., Franklin, M. J., Jay-Dixon, J., Sadiq, A., De, A., Graff, J. R. & Kratzke, R. A., Aug 18 2015, In : Cancer gene therapy. 22, 8, p. 396-401 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Endometrial metastasis of lung adenocarcinoma: A report of two cases

Ahmad, Z., Raza, A. & Patel, M. R., May 18 2015, In : American Journal of Case Reports. 16, p. 296-299 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Genetic Engineering of Oncolytic Viruses for Cancer Therapy

Patel, M. R. & Kratzke, R. A., Jan 1 2015, Translating Gene Therapy to the Clinic: Techniques and Approaches. Elsevier Inc., p. 261-279 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Targeting topoisomerase II activity in NSCLC with 9-aminoacridine derivatives

Ferguson, D. M., Jacobson, B. A., Jay-Dixon, J., Patel, M. R., Kratzke, R. A. & Raza, A., Jan 1 2015, In : Anticancer Research. 35, 10, p. 5211-5218 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma

Jacobson, B. A., Chen, E. Z., Tang, S., Belgum, H. S., McCauley, J. A., Evenson, K. A., Etchison, R. G., Jay-Dixon, J., Patel, M. R., Raza, A., Saluja, A. K., D’Cunha, J. & Kratzke, R. A., Jan 1 2015, In : Genes and Cancer. 6, 3-4, p. 144-152 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Vesicular stomatitis virus expressing interferon-β is oncolytic and promotes antitumor immune responses in a syngeneic murine model of non-small cell lung cancer

Patel, M. R., Jacobson, B. A., Ji, Y., Drees, J., Tang, S., Xiong, K., Wang, H., Prigge, J. E., Dash, A. S., Kratzke, A. K., Mesev, E., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Jan 1 2015, In : Oncotarget. 6, 32, p. 33165-33177 13 p.

Research output: Contribution to journalArticle

37 Scopus citations
2014

An absolute obstacle: Cardiac metastasis of synovial sarcoma

Vakil, K. P., Raza, A., Zakharova, M. Y., Madlon-Kay, R., Skubitz, K. M. & Patel, M. R., May 2014, In : American Journal of Medicine. 127, 5, p. 390-392 3 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Measles vaccine strains for virotherapy of non-small-cell lung carcinoma

Patel, M. R., Jacobson, B. A., Belgum, H., Raza, A., Sadiq, A., Drees, J., Wang, H., Jay-Dixon, J., Etchison, R., Federspiel, M. J., Russell, S. J. & Kratzke, R. A., Aug 2014, In : Journal of Thoracic Oncology. 9, 8, p. 1101-1110 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Small-molecule inhibition of oncogenic eukaryotic protein translation in mesothelioma cells

Chen, E. Z., Jacobson, B. A., Patel, M. R., Okon, A. M., Li, S., Xiong, K., Vaidya, A. J., Bitterman, P. B., Wagner, C. R. & Kratzke, R. A., Aug 2014, In : Investigational New Drugs. 32, 4, p. 598-603 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Oncolytic virus therapy for cancer: The first wave of translational clinical trials

Patel, M. R. & Kratzke, R. A., Apr 2013, In : Translational Research. 161, 4, p. 355-364 10 p.

Research output: Contribution to journalReview article

61 Scopus citations
11 Scopus citations

Targeting eukaryotic translation in mesothelioma cells with an eIF4E-specific antisense oligonucleotide

Jacobson, B. A., Thumma, S. C., Jay-Dixon, J., Patel, M. R., Dubear Kroening, K., Kratzke, M. G., Etchison, R. G., Konicek, B. W., Graff, J. R. & Kratzke, R. A., Nov 18 2013, In : PloS one. 8, 11, e81669.

Research output: Contribution to journalArticle

22 Scopus citations
2012
11 Scopus citations

Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation

Patel, M. R., Sadiq, A. A., Jay-Dixon, J., Jirakulaporn, T., Jacobson, B. A., Farassati, F., Bitterman, P. B. & Kratzke, R. A., Feb 1 2012, In : International Journal of Oncology. 40, 2, p. 577-582 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2011

Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues

Kodali, D., Rawal, A., Ninan, M. J., Patel, M. R., Mesa, H., Knapp, D., Schnitzer, B., Kratzke, R. A. & Gupta, P., Mar 1 2011, In : Archives of Pathology and Laboratory Medicine. 135, 3, p. 365-371 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2010

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II

Sadiq, A. A., Patel, M. R., Jacobson, B. A., Escobedo, M., Ellis, K., Oppegard, L. M., Hiasa, H. & Kratzke, R. A., Jan 1 2010, In : Investigational New Drugs. 28, 1, p. 20-25 6 p.

Research output: Contribution to journalArticle

23 Scopus citations
2009

Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma

Jacobson, B. A., De, A., Kratzke, M. G., Patel, M. R., Jay-Dixon, J., Whitson, B. A., Sadiq, A. A., Bitterman, P. B., Polunovsky, V. A. & Kratzke, R. A., Aug 4 2009, In : British Journal of Cancer. 101, 3, p. 424-431 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2008

Vitamin D intake to attain a desired serum 25-hydroxyvitamin D concentration

Aloia, J. F., Patel, M., DiMaano, R., Li-Ng, M., Talwar, S. A., Mikhail, M., Pollack, S. & Yeh, J. K., Jun 1 2008, In : American Journal of Clinical Nutrition. 87, 6, p. 1952-1958 7 p.

Research output: Contribution to journalArticle

239 Scopus citations
2007

Ras pathway activation in malignant mesothelioma

Patel, M. R., Jacobson, B. A., De, A., Frizelle, S. P., Janne, P., Thumma, S. C., Whitson, B. A., Farassati, F. & Kratzke, R. A., Sep 1 2007, In : Journal of Thoracic Oncology. 2, 9, p. 789-795 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2006

Effects of Insulin-Like Growth Factor-1 Receptor Inhibition in Mesothelioma

Whitson, B. A., Jacobson, B. A., Frizelle, S., Patel, M. R., Yee, D., Maddaus, M. A. & Kratzke, R. A., Sep 1 2006, In : Annals of Thoracic Surgery. 82, 3, p. 996-1002 7 p.

Research output: Contribution to journalArticle

18 Scopus citations