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Luke H Hoeppner

20062020
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Projects 2015 2020

Combating lung cancer resistance to EGFR targeted therapy

Hoeppner, L. H., Aslanidi, G. & Yang, R.

PARDEE FDN

1/1/20 → 12/31/20

Project: Research project

Lung Neoplasms
Therapeutics

Triggering the dopamine pathway to inhibit lung cancer p

Hoeppner, L. H.

NIH NATIONAL CANCER INSTITUTE (NCI)

9/10/15 → 8/31/18

Project: Research project

Dopamine
Lung Neoplasms

Research Output 2006 2019

Protein kinase D up-regulates transcription of VEGF receptor-2 in endothelial cells by suppressing nuclear localization of the transcription factor AP2β

Wang, Y., Hoeppner, L. H., Angom, R. S., Wang, E., Dutta, S., Doeppler, H. R., Wang, F., Shen, T., Scarisbrick, I. A., Guha, S., Storz, P., Bhattacharya, R. & Mukhopadhyay, D., Jan 1 2019, In : Journal of Biological Chemistry. 294, 43, p. 15759-15767 9 p.

Research output: Contribution to journal › Article

Transcription Factor AP-2
Vascular Endothelial Growth Factor Receptor-2
Vascular Endothelial Growth Factor Receptor
Endothelial cells
Transcription
5 Citations (Scopus)

ScanNeo: Identifying indel-derived neoantigens using RNA-Seq data

Wang, T. Y., Wang, L., Alam, S. K., Hoeppner, L. H., Yang, R. & Birol, I., Oct 15 2019, In : Bioinformatics. 35, 20, p. 4159-4161 3 p.

Research output: Contribution to journal › Article

RNA
Melanoma
DNA Sequencing
Python
Prostate Cancer
2 Citations (Scopus)

BMI1 drives metastasis of prostate cancer in Caucasian and African-American men and is a potential therapeutic target: Hypothesis Tested in Race-specific Models

Ganaie, A. A., Beigh, F. H., Astone, M., Ferrari, M. G., Maqbool, R., Umbreen, S., Parray, A. S., Siddique, H. R., Hussain, T., Murugan, P., Morrissey, C., Koochekpour, S., Deng, Y., Konety, B. R., Hoeppner, L. H. & Saleem, M., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6421-6432 12 p.

Research output: Contribution to journal › Article

Open Access
African Americans
Prostatic Neoplasms
Neoplasm Metastasis
Neoplasms
docetaxel
1 Citation (Scopus)

Correction: RhoC maintains vascular homeostasis by regulating VEGF-induced signaling in endothelial cells [J. Cell Sci., 128, (3556-3568)] doi:10.1242/jcs.167601

Hoeppner, L. H., Sinha, S., Wang, Y., Bhattacharya, R., Dutta, S., Gong, X., Bedell, V. M., Suresh, S., Chun, C., Ramchandran, R., Ekker, S. C. & Mukhopadhyay, D., Mar 1 2018, In : Journal of cell science. 131, 6, jcs217604.

Research output: Contribution to journal › Comment/debate

Zebrafish
Vascular Endothelial Growth Factor A
Blood Vessels
Homeostasis
Endothelial Cells
3 Citations (Scopus)

DARPP-32 and t-DARPP promote non-small cell lung cancer growth through regulation of IKKα-dependent cell migration

Alam, S. K., Astone, M., Liu, P., Hall, S. R., Coyle, A. M., Dankert, E. N., Hoffman, D. K., Zhang, W., Kuang, R., Roden, A. C., Mansfield, A. S. & Hoeppner, L. H., Dec 1 2018, In : Communications Biology. 1, 1, 43.

Research output: Contribution to journal › Article

Open Access
phosphoproteins
Phosphoproteins
cyclic AMP
lung neoplasms
dopamine