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Research Output 2003 2019

Abstract

Coronary Revascularization Procedures in Children: in-Hospital Mortality and Mid-Term Follow Up Data

Kochilas, L., Menk, J., Vinocur, J., Harvey, B., Spector, L. G. & Louis, J. S., 2016.

Research output: Contribution to conferenceAbstract

Percutaneous Coronary Intervention
Hospital Mortality
Coronary Artery Bypass
Article
2-ethyleneimino-5,6,7,8-tetrahydronaphthoquinone
Rheumatology
Referral and Consultation
Pediatrics
Antinuclear Antibodies
Rheumatology
Referral and Consultation
Pediatrics
Pediatricians
3 Citations (Scopus)
Genome-Wide Association Study
Osteosarcoma
Single Nucleotide Polymorphism
Genes
Bone Neoplasms
22 Citations (Scopus)

A case-control study of childhood brain tumors and fathers' hobbies: A Children's Oncology Group study

Rosso, A. L., Hovinga, M. E., Rorke-Adams, L. B., Spector, L. G. & Bunin, G. R., Dec 1 2008, In : Cancer Causes and Control. 19, 10, p. 1201-1207 7 p.

Research output: Contribution to journalArticle

Hobbies
Primitive Neuroectodermal Tumors
Brain Neoplasms
Fathers
Medulloblastoma

A comparison of risk factors for metastasis at diagnosis in humans and dogs with osteosarcoma

Diessner, B. J., Marko, T. A., Scott, R. M., Eckert, A. L., Stuebner, K. M., Hohenhaus, A. E., Selting, K. A., Largaespada, D. A., Modiano, J. & Spector, L. G., Jun 2019, In : Cancer medicine. 8, 6, p. 3216-3226 11 p.

Research output: Contribution to journalArticle

Open Access
Osteosarcoma
Dogs
Neoplasm Metastasis
Neoplasms
Canidae
6 Citations (Scopus)

Advanced parental age as risk factor for childhood acute lymphoblastic leukemia: results from studies of the Childhood Leukemia International Consortium

Petridou, E. T., Georgakis, M. K., Erdmann, F., Ma, X., Heck, J. E., Auvinen, A., Mueller, B. A., Spector, L. G., Roman, E., Metayer, C., Magnani, C., Pombo-de-Oliveira, M. S., Ezzat, S., Scheurer, M. E., Mora, A. M., Dockerty, J. D., Hansen, J., Kang, A. Y., Wang, R., Doody, D. R. & 6 others, Kane, E., Rashed, W. M., Dessypris, N., Schüz, J., Infante-Rivard, C. & Skalkidou, A., 2018, In : European Journal of Epidemiology. 33, 10

Research output: Contribution to journalArticle

Open Access
Paternal Age
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Maternal Age
Leukemia
Parents
50 Citations (Scopus)

A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma

Mirabello, L., Koster, R., Moriarity, B. S., Spector, L. G., Meltzer, P. S., Gary, J., Machiela, M. J., Pankratz, N., Panagiotou, O. A., Largaespada, D., Wang, Z., Gastier-Foster, J. M., Gorlick, R., Khanna, C., de Toledo, S. R. C., Petrilli, A. S., Patiño-Garcia, A., Sierrasesúmaga, L., Lecanda, F., Andrulis, I. L. & 32 others, Wunder, J. S., Gokgoz, N., Serra, M., Hattinger, C., Picci, P., Scotlandi, K., Flanagan, A. M., Tirabosco, R., Amary, M. F., Halai, D., Ballinger, M. L., Thomas, D. M., Davis, S., Barkauskas, D. A., Marina, N., Helman, L., Otto, G. M., Becklin, K. L., Wolf, N. K., Weg, M. T., Tucker, M., Wacholder, S., Fraumeni, J. F., Caporaso, N. E., Boland, J. F., Hicks, B. D., Vogt, A., Burdett, L., Yeager, M., Hoover, R. N., Chanock, S. J. & Savage, S. A., Sep 1 2015, In : Cancer discovery. 5, 9, p. 920-931 12 p.

Research output: Contribution to journalArticle

Osteosarcoma
Genome
Neoplasm Metastasis
Cause of Death
Genome-Wide Association Study
11 Citations (Scopus)

Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: A report from the children's oncology group

Lupo, P. J., Zhou, R., Skapek, S. X., Hawkins, D. S., Spector, L. G., Scheurer, M. E., Fatih Okcu, M., Melin, B., Papworth, K., Erhardt, E. B. & Grufferman, S., Jan 15 2014, In : International Journal of Cancer. 134, 2, p. 431-436 6 p.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Immunologic Factors
Hypersensitivity
Odds Ratio
Confidence Intervals

Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: A report from the children's oncology group

Lupo, P. J., Zhou, R., Skapek, S. X., Hawkins, D. S., Spector, L. G., Scheurer, M. E., Fatih Okcu, M., Melin, B., Papworth, K., Erhardt, E. B. & Grufferman, S., 2014, In : International Journal of Cancer. 134, 2

Research output: Contribution to journalArticle

Open Access
Rhabdomyosarcoma
Immunologic Factors
Hypersensitivity
Odds Ratio
Confidence Intervals
5 Citations (Scopus)

Analgesic use during pregnancy and risk of infant leukaemia: A Children's Oncology Group study

Ognjanovic, S., Blair, C., Spector, L. G., Robison, L. L., Roesler, M. & Ross, J. A., Feb 1 2011, In : British Journal of Cancer. 104, 3, p. 532-536 5 p.

Research output: Contribution to journalArticle

Analgesics
Leukemia
Pregnancy
Non-Steroidal Anti-Inflammatory Agents
Acetaminophen

Analgesic use during pregnancy and risk of infant leukaemia: A Children's Oncology Group study

Ognjanovic, S., Blair, C. K., Spector, L. G., Robison, L. L., Roesler, M. & Ross, J. A., 2011, In : British Journal of Cancer. 104

Research output: Contribution to journalArticle

Analgesics
Leukemia
Pregnancy
Non-Steroidal Anti-Inflammatory Agents
Acetaminophen
3 Citations (Scopus)

An analysis of measures of effect size by age of onset in cancer genomewide association studies

Raynor, L. A., Pankratz, N. & Spector, L. G., Sep 1 2013, In : Genes Chromosomes and Cancer. 52, 9, p. 855-859 5 p.

Research output: Contribution to journalArticle

Age of Onset
Neoplasms
Genome-Wide Association Study
National Human Genome Research Institute (U.S.)
Odds Ratio
4 Citations (Scopus)
Cell Transplantation
Haplotypes
Tissue Donors
Confidence Intervals
Siblings
24 Citations (Scopus)

ARID5B and IKZF1 variants, selected demographic factors, and childhood acute lymphoblastic leukemia: A report from the Children's Oncology Group

Linabery, A. M., Blommer, C. N., Spector, L. G., Davies, S. M., Robison, L. L. & Ross, J. A., Aug 1 2013, In : Leukemia Research. 37, 8, p. 936-942 7 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Demography
Polyploidy
Birth Weight
Odds Ratio
17 Citations (Scopus)

Assisted reproductive technology use and outcomes among women with a history of cancer

Luke, B., Brown, M. B., Missmer, S. A., Spector, L. G., Leach, R. E., Williams, M., Koch, L., Smith, Y. R., Stern, J. E., Ball, G. D. & Schymura, M. J., Jan 1 2016, In : Human Reproduction. 31, 1, p. 183-189 7 p.

Research output: Contribution to journalArticle

Assisted Reproductive Techniques
Neoplasms
Live Birth
Oocytes
Birth Rate
3 Citations (Scopus)

Association of in Vitro Fertilization with Childhood Cancer in the United States

Spector, L. G., Brown, M. B., Wantman, E., Letterie, G. S., Toner, J. P., Doody, K., Ginsburg, E., Williams, M., Koch, L., Schymura, M. J. & Luke, B., Jun 2019, In : JAMA Pediatrics. 173, 6

Research output: Contribution to journalArticle

Fertilization in Vitro
Neoplasms
Parturition
Multiple Birth Offspring
Liver
9 Citations (Scopus)

Association of rib anomalies and childhood cancers

Zierhut, H., Murati, M., Holm, T., Hoggard, E. & Spector, L. G., Oct 25 2011, In : British Journal of Cancer. 105, 9, p. 1392-1395 4 p.

Research output: Contribution to journalArticle

Ribs
Neoplasms
Hepatoblastoma
Acute Myeloid Leukemia
Case-Control Studies
5 Citations (Scopus)
Rheumatology
Referral and Consultation
Pediatrics
Pediatricians
Surveys and Questionnaires
59 Citations (Scopus)

Bias in studies of parental self-reported occupational exposure and childhood cancer

Schüz, J., Spector, L. G. & Ross, J. A., Oct 1 2003, In : American journal of epidemiology. 158, 7, p. 710-716 7 p.

Research output: Contribution to journalArticle

Occupational Exposure
Case-Control Studies
Interviews
Neoplasms
Validation Studies
9 Citations (Scopus)

Biomarker evidence of tobacco smoke exposure in children participating in lead screening

Joseph, A., Spector, L., Wickham, K., Janis, G., Winickoff, J., Lindgren, B. & Murphy, S., Dec 1 2013, In : American journal of public health. 103, 12, p. e54-e59

Research output: Contribution to journalArticle

Cotinine
Smoke
Tobacco
Biomarkers
Medicaid
33 Citations (Scopus)

Birth characteristics, maternal reproductive history, and the risk of infant leukemia: A report from the children's oncology group

Spector, L. G., Davies, S. M., Robison, L. L., Hilden, J. M., Roesler, M. & Ross, J. A., Jan 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 1, p. 128-134 7 p.

Research output: Contribution to journalArticle

Reproductive History
Leukemia
Mothers
Parturition
Birth Weight
13 Citations (Scopus)

Birth characteristics and childhood carcinomas

Johnson, K. J., Carozza, S. E., Chow, E. J., Fox, E. E., Horel, S., McLaughlin, C. C., Mueller, B. A., Puumala, S. E., Reynolds, P., Von Behren, J. & Spector, L. G., Oct 25 2011, In : British Journal of Cancer. 105, 9, p. 1396-1401 6 p.

Research output: Contribution to journalArticle

Odds Ratio
Parturition
Confidence Intervals
Carcinoma
Melanoma
31 Citations (Scopus)

Birth characteristics and the risk of childhood rhabdomyosarcoma based on histological subtype

Ognjanovic, S., Carozza, S. E., Chow, E. J., Fox, E. E., Horel, S., McLaughlin, C. C., Mueller, B. A., Puumala, S., Reynolds, P., Von Behren, J. & Spector, L., Jan 1 2010, In : British Journal of Cancer. 102, 1, p. 227-231 5 p.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Embryonal Rhabdomyosarcoma
Birth Weight
Alveolar Rhabdomyosarcoma
Parturition
19 Citations (Scopus)

Birth characteristics and Wilms tumor in Minnesota

Puumala, S. E., Soler, J. T., Johnson, K. J. & Spector, L. G., Mar 15 2008, In : International Journal of Cancer. 122, 6, p. 1368-1373 6 p.

Research output: Contribution to journalArticle

Wilms Tumor
Parturition
Birth Weight
Gestational Age
Birth Certificates
49 Citations (Scopus)

Birth order and risk of childhood cancer: A pooled analysis from five US States

Von Behren, J., Spector, L. G., Mueller, B. A., Carozza, S. E., Chow, E. J., Fox, E. E., Horel, S., Johnson, K. J., McLaughlin, C., Puumala, S. E., Ross, J. A. & Reynolds, P., Jun 1 2011, In : International Journal of Cancer. 128, 11, p. 2709-2716 8 p.

Research output: Contribution to journalArticle

Birth Order
Neoplasms
Parturition
Multiple Birth Offspring
Central Nervous System Neoplasms
5 Citations (Scopus)

Birth weight and subsequent risk of childhood primary brain tumors: An updated meta-analysis

Dahlhaus, A., Prengel, P., Spector, L. & Pieper, D., May 1 2017, In : Pediatric Blood and Cancer. 64, 5, e26299.

Research output: Contribution to journalArticle

Primitive Neuroectodermal Tumors
Medulloblastoma
Birth Weight
Brain Neoplasms
Meta-Analysis
22 Citations (Scopus)

Caesarean delivery and risk of childhood leukaemia: A pooled analysis from the Childhood Leukemia International Consortium (CLIC)

Marcotte, E. L., Thomopoulos, T. P., Infante-Rivard, C., Clavel, J., Petridou, E. T., Schüz, J., Ezzat, S., Dockerty, J. D., Metayer, C., Magnani, C., Scheurer, M. E., Mueller, B. A., Mora, A. M., Wesseling, C., Skalkidou, A., Rashed, W. M., Francis, S. S., Ajrouche, R., Erdmann, F., Orsi, L. & 1 others, Spector, L. G., Apr 1 2016, In : The Lancet Haematology. 3, 4, p. e176-e185

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Acute Myeloid Leukemia
Odds Ratio
Emergencies
18 Citations (Scopus)

Cancer in women after assisted reproductive technology

Luke, B., Brown, M. B., Spector, L. G., Missmer, S. A., Leach, R. E., Williams, M., Koch, L., Smith, Y., Stern, J. E., Ball, G. D. & Schymura, M. J., Nov 2015, In : Fertility and Sterility. 104, 5, p. 1218-1226 9 p.

Research output: Contribution to journalArticle

Assisted Reproductive Techniques
Neoplasms
Confidence Intervals
Registries
Incidence

Cancer in women before ART

Luke, B., Brown, M. B., Spector, L. G., Missmer, S., Leach, R., Williams, M., Koch, L., Smith, Y. R., Stern, J., Ball, G. D. & Schymura, M. J., 2014, In : Fertility and Sterility. 102

Research output: Contribution to journalArticle

Cancer patterns in Hmong in Minnesota, 2000 to 2012

Oyenuga, M., Yang, J. K., Prizment, A. E., Bushhouse, S., Demerath, E. W. & Spector, L. G., Sep 1 2018, In : Cancer. 124, 17, p. 3560-3566 7 p.

Research output: Contribution to journalArticle

Confidence Intervals
Neoplasms
Incidence
Uterine Cervical Neoplasms
Melanoma
67 Citations (Scopus)

Cancer risk among children with very low birth weights

Spector, L. G., Puumala, S. E., Carozza, S. E., Chow, E. J., Fox, E. E., Horel, S., Johnson, K. J., McLaughlin, C. C., Reynolds, P., Von Behren, J. & Mueller, B. A., Jul 1 2009, In : Pediatrics. 124, 1, p. 96-104 9 p.

Research output: Contribution to journalArticle

Very Low Birth Weight Infant
Neoplasms
Glioma
Hepatoblastoma
Retinoblastoma
20 Citations (Scopus)

Case-parent analysis of variation in pubertal hormone genes and pediatric osteosarcoma: A children's oncology group (COG) study

Musselman, J. R. B., Bergemann, T. L., Ross, J. A., Sklar, C., Silverstein, K. A. T., Langer, E. K., Savage, S. A., Nagarajan, R., Krailo, M., Malkin, D. & Spector, L. G., Nov 27 2012, In : International Journal of Molecular Epidemiology and Genetics. 3, 4, p. 286-293 8 p.

Research output: Contribution to journalArticle

Osteosarcoma
Hormones
Pediatrics
Genes
Single Nucleotide Polymorphism
37 Citations (Scopus)

Child and maternal household chemical exposure and the risk of acute leukemia in children with Down's syndrome: A report from the children's oncology group

Alderton, L. E., Spector, L. G., Blair, C. K., Roesler, M., Olshan, A. F., Robison, L. L. & Ross, J. A., Aug 1 2006, In : American journal of epidemiology. 164, 3, p. 212-221 10 p.

Research output: Contribution to journalArticle

Down Syndrome
Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Mothers
Odds Ratio
39 Citations (Scopus)

Childhood acute lymphoblastic leukemia and indicators of early immune stimulation: A childhood leukemia international consortium study

Rudant, J., Lightfoot, T., Urayama, K. Y., Petridou, E., Dockerty, J. D., Magnani, C., Milne, E., Spector, L. G., Ashton, L. J., Dessypris, N., Kang, A. Y., Miller, M., Rondelli, R., Simpson, J., Stiakaki, E., Orsi, L., Roman, E., Metayer, C., Infante-Rivard, C. & Clavel, J., Dec 19 2015, In : American journal of epidemiology. 181, 8, p. 549-562 14 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Breast Feeding
Odds Ratio
Confidence Intervals
27 Citations (Scopus)

Childhood and maternal infections and risk of acute leukaemia in children with Down syndrome: A report from the Children's Oncology Group

Canfield, K. N., Spector, L. G., Robison, L. L., Lazovich, D., Roesler, M., Olshan, A. F., Smith, F. O., Heerema, N. A., Barnard, D. R., Blair, C. K. & Ross, J. A., Nov 29 2004, In : British Journal of Cancer. 91, 11, p. 1866-1872 7 p.

Research output: Contribution to journalArticle

Down Syndrome
Leukemia
Mothers
Infection
Odds Ratio
19 Citations (Scopus)

Childhood cancer among twins and higher order multiples

Puumala, S. E., Carozza, S. E., Chow, E. J., Fox, E. E., Horel, S., Johnson, K. J., McLaughlin, C., Mueller, B. A., Reynolds, P., Von Behren, J. & Spector, L. G., Jan 1 2009, In : Cancer Epidemiology Biomarkers and Prevention. 18, 1, p. 162-168 7 p.

Research output: Contribution to journalArticle

Odds Ratio
Confidence Intervals
Parturition
Wilms Tumor
Birth Weight
6 Citations (Scopus)

Childhood cancer and birthmarks in the Collaborative Perinatal Project

Johnson, K. J., Spector, L. G., Klebanoff, M. A. & Ross, J. A., May 1 2007, In : Pediatrics. 119, 5, p. e1088-e1093

Research output: Contribution to journalArticle

Neoplasms
Lymphangioma
Pigmented Nevus
Fragaria
Wine
95 Citations (Scopus)

Childhood cancer following neonatal oxygen supplementation

Spector, L. G., Klebanoff, M. A., Feusner, J. H., Georgieff, M. K. & Ross, J. A., Jul 1 2005, In : Journal of Pediatrics. 147, 1, p. 27-31 5 p.

Research output: Contribution to journalArticle

Confidence Intervals
Oxygen
Neoplasms
7 Citations (Scopus)

Childhood cancer incidence in relation to sunlight exposure

Musselman, J. R. B. & Spector, L. G., Jan 4 2011, In : British Journal of Cancer. 104, 1, p. 214-220 7 p.

Research output: Contribution to journalArticle

Sunlight
Incidence
Registries
Neoplasms
Radiation
41 Citations (Scopus)

Childhood cancer in relation to parental race and ethnicity a 5-state pooled analysis

Chow, E. J., Puumala, S. E., Mueller, B. A., Carozza, S. E., Fox, E. E., Horel, S., Johnson, K. J., McLaughlin, C. C., Reynolds, P., Von Behren, J. & Spector, L. G., Jun 15 2010, In : Cancer. 116, 12, p. 3045-3053 9 p.

Research output: Contribution to journalArticle

Odds Ratio
Confidence Intervals
Neoplasms
Hispanic Americans
Birth Certificates
23 Citations (Scopus)

Childhood cancer in the offspring born in 1921-1984 to US radiologic technologists

Johnson, K. J., Alexander, B. H., Doody, M. M., Sigurdson, A. J., Linet, M. S., Spector, L. G., Hoffbeck, R. W., Simon, S. L., Weinstock, R. M. & Ross, J. A., Aug 5 2008, In : British Journal of Cancer. 99, 3, p. 545-550 6 p.

Research output: Contribution to journalArticle

Paternal Exposure
Neoplasms
Occupational Exposure
Radiation Exposure
7 Citations (Scopus)

Childhood cancer risk in those with chromosomal and non-chromosomal congenital anomalies in Washington State: 1984-2013

Norwood, M. S., Lupo, P. J., Chow, E. J., Scheurer, M. E., Plon, S. E., Danysh, H. E., Spector, L. G., Carozza, S. E., Doody, D. R. & Mueller, B. A., Jun 2017, In : PloS one. 12, 6, e0179006.

Research output: Contribution to journalArticle

Open Access
childhood
neoplasms
Neoplasms
odds ratio
Neurology
46 Citations (Scopus)

Common occurrence of monoclonal B-cell lymphocytosis among members of high-risk CLL families

Goldin, L. R., Lanasa, M. C., Slager, S. L., Cerhan, J. R., Vachon, C. M., Strom, S. S., Camp, N. J., Spector, L. G., Leis, J. F., Morrison, V. A., Glenn, M., Rabe, K. G., Achenbach, S. J., Algood, S. D., Abbasi, F., Fontaine, L., Yau, M., Rassenti, L. Z., Kay, N. E., Call, T. G. & 4 others, Hanson, C. A., Weinberg, J. B., Marti, G. E. & Caporaso, N. E., Oct 1 2010, In : British Journal of Haematology. 151, 2, p. 152-158 7 p.

Research output: Contribution to journalArticle

Lymphocytosis
B-Cell Chronic Lymphocytic Leukemia
B-Lymphocytes
Asymptomatic Diseases
Age Distribution
41 Citations (Scopus)

Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia

Slager, S. L., Skibola, C. F., Di Bernardo, M. C., Conde, L., Broderick, P., McDonnell, S. K., Goldin, L. R., Croft, N., Holroyd, A., Harris, S., Riby, J., Serie, D. J., Kay, N. E., Call, T. G., Bracci, P. M., Halperin, E., Lanasa, M. C., Cunningham, J. M., Leis, J. F., Morrison, V. A. & 14 others, Spector, L. G., Vachon, C. M., Shanafelt, T. D., Strom, S. S., Camp, N. J., Weinberg, J. B., Matutes, E., Caporaso, N. E., Wade, R., Dyer, M. J. S., Dearden, C., Cerhan, J. R., Catovsky, D. & Houlston, R. S., Jul 26 2012, In : Blood. 120, 4, p. 843-846 4 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Genes
Multifactorial Inheritance
Genome-Wide Association Study
Meta-Analysis
18 Citations (Scopus)

Comparability and representativeness of control groups in a case-control study of infant leukemia: A report from the children's oncology group

Ross, J. A., Puumala, S. E., Spector, L. G., Robison, L. L., Bunin, G. R., Olshan, A. F., Linabery, A. M., Roesler, M. A. & Blair, C. K., Aug 1 2009, In : American journal of epidemiology. 170, 3, p. 379-387 9 p.

Research output: Contribution to journalArticle

Birth Certificates
Case-Control Studies
Contraception
Leukemia
Control Groups

Comparability and representativeness of control groups in a case-control study of infant leukemia: a report from the Children's Oncology Group.

Puumala, S. E., Spector, L. G., Robison, L. L., Bunin, G. R., Olshan, A. F., Linabery, A. M., Roesler, M. A., Blair, C. K. & Ross, J. A., 2009, In : American Journal of Epidemiology. 170, 3

Research output: Contribution to journalArticle

Birth Certificates
Case-Control Studies
Contraception
Leukemia
Control Groups
16 Citations (Scopus)
Open Access
Gene Expression Profiling
Osteosarcoma
Survival
Multigene Family
Neoplasms
11 Citations (Scopus)

Congenital abnormalities and hepatoblastoma: A report from the Children's Oncology Group (COG) and the Utah Population Database (UPDB)

Venkatramani, R., Spector, L. G., Georgieff, M., Tomlinson, G., Krailo, M., Malogolowkin, M., Kohlmann, W., Curtin, K., Fonstad, R. K. & Schiffman, J. D., Sep 2014, In : American Journal of Medical Genetics, Part A. 164, 9, p. 2250-2255 6 p.

Research output: Contribution to journalArticle

Hepatoblastoma
Population Groups
Odds Ratio
Databases
Confidence Intervals