Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Improving outcomes in HIV-associated opportunistic infections using CNS pharmacokinetics and pharmacodynamics
Nicol, M. R. (PI), Boulware, D. R. (CoI) & Coles, L. D. (CoI)
NATIONAL INSTITUTES OF HEALTH (NIH)
8/18/24 → 5/31/29
Project: Research project
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AbbVie-UMN Clinical Pharmacology and Pharmacometrics Fellowship
Coles, L. D. (PI)
11/30/22 → 5/31/25
Project: Research project
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NEOLEV3: A Phase IIb Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures of Mild to Moderate Severity IND-109622 (September 6, 2020)
Wang, S. (PI), Coles, L. D. (CoI) & Pfister, K. M. (CoI)
DHHS FOOD & DRUG ADMINISTRATION (FDA)
9/20/22 → 7/31/27
Project: Research project
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Leveraging innate immunity to prevent post-traumatic epilepsy
Coles, L. D. (PI)
UNIVERSITY OF CALIFORNIA, LOS ANGELES, U.S. DEPARTMENT OF DEFENSE
7/1/22 → 6/30/25
Project: Research project
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LC-MS/MS Assay and Pharmacokinetic Analysis of Plasma Atorvastatin Concentrations In Rats
Cloyd, J. C. (PI), Coles, L. D. (CoI) & Mishra, U. (Other Role)
7/1/24 → 12/31/24
Project: Research project
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Efficacy and tolerability of celastrol and edaravone in the multiple-hit rat model of infantile spasms
Shandra, O., Wang, Y., Coles, L. D., Mowrey, W. B., Li, Q., Liu, W., Moshé, S. L. & Galanopoulou, A. S., Jan 2025, In: Epilepsy and Behavior. 162, 110159.Research output: Contribution to journal › Article › peer-review
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Pharmacokinetics and brain uptake of sodium selenate and selenium in naïve rats and a lateral fluid percussion injury rat model
Li, C., Casillas-Espinosa, P. M., Saletti, P. G., Chi, T., Yamakawa, G., Silva, J., Hudson, M., Liu, W., Jones, N. C., Shultz, S. R., Ali, I., Mishra, U., Cloyd, J. C., Moshe ́, S. L., Galanopoulou, A. S., O'Brien, T. J. & Coles, L. D., Dec 2024, In: Pharmacology Research and Perspectives. 12, 6, e1256.Research output: Contribution to journal › Article › peer-review
Open Access -
Tau Phosphorylation Patterns in the Rat Cerebral Cortex After Traumatic Brain Injury and Sodium Selenate Effects: An Epibios4rx Project 2 Study
EpiBioS4Rx Study Group, Jan 1 2024, In: Journal of neurotrauma. 41, 1-2, p. 222-243 22 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Early preclinical plasma protein biomarkers of brain trauma are influenced by early seizures and levetiracetam
For the EpiBioS4Rx Study Group, Jun 2023, In: Epilepsia Open. 8, 2, p. 586-608 23 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Levetiracetam Pharmacokinetics and Brain Uptake in a Lateral Fluid Percussion Injury Rat Model
EpiBioS4Rx Study Group, Aug 1 2023, In: Journal of Pharmacology and Experimental Therapeutics. 386, 2, p. 259-265 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations