Liqiang Chen

20022019
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Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Histone Deacetylase Inhibitors Medicine & Life Sciences
Sirtuin 2 Medicine & Life Sciences

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Research Output 2002 2019

Discovery of Irreversible p97 Inhibitors

Ding, R., Zhang, T., Wilson, D., Xie, J., Williams, J. M., Xu, Y., Ye, Y. & Chen, L., Mar 14 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2814-2829 16 p.

Research output: Contribution to journalArticle

Amides
Mutagenesis
Cysteine
Mass Spectrometry
Neoplasms
2 Citations (Scopus)

UNC-45A is a novel microtubule-associated protein and regulator of paclitaxel sensitivity in ovarian cancer cells

Mooneyham, A., Iizuka, Y., Yang, Q., Coombes, C., McClellan, M., Shridhar, V., Emmings, E., Shetty, M., Chen, L., Ai, T., Meints, J., Lee, M. K., Gardner, M. K. & Bazzaro, M., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 370-383 14 p.

Research output: Contribution to journalArticle

Microtubule-Associated Proteins
Paclitaxel
Ovarian Neoplasms
Spindle Apparatus
Microtubules
4 Citations (Scopus)

N-(1-Benzyl-3,5-dimethyl‑1H‑pyrazol-4-yl)benzamides: Antiproliferative activity and effects on mTORC1 and autophagy

Ai, T., Willett, R., Williams, J., Ding, R., Wilson, D., Xie, J., Kim, D-H., Puertollano, R. & Chen, L., Jan 1 2017, In : ACS Medicinal Chemistry Letters. 8, 1, p. 90-95 6 p.

Research output: Contribution to journalArticle

Open Access
Benzamides
Autophagy
Starvation
Modulators
Fluxes
10 Citations (Scopus)

5-((3-Amidobenzyl)oxy)nicotinamides as Sirtuin 2 Inhibitors

Ai, T., Wilson, D., More, S. S., Xie, J. & Chen, L., Apr 28 2016, In : Journal of Medicinal Chemistry. 59, 7, p. 2928-2941 14 p.

Research output: Contribution to journalArticle

Sirtuin 2
Niacinamide
Synucleins
NAD
Isoenzymes

A novel sirtuin-3 inhibitor, LC-0296, inhibits cell survival and proliferation, and promotes apoptosis of head and neck cancer cells

Alhazzazi, T. Y., Kamarajan, P., Xu, Y., Ai, T., Chen, L., Verdin, E. & Kapila, Y. L., Jan 1 2016, In : Anticancer Research. 36, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

Sirtuin 3
Head and Neck Neoplasms
Cell Survival
Cell Proliferation
Apoptosis