Liqiang Chen

Assistant Professor, Center for Drug Design

Emailchenx462@umn.edu

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2 Active

Optimizing Zika NS5 Methyltransferase Inhibitors
Chen, L., Geraghty, R. J. & Xie, J.
NIH Nat'l Inst of Allergy & Infect Dis
2/1/20 → 1/31/22
Project: Research project
Exploiting SIRT2 for Breast Cancer Therapy
Chen, L.
Emory University
8/1/19 → 7/31/21
Project: Research project

35 Article
2 Review article

Anti-HCMV activity by an irreversible p97 inhibitor LC-1310
Wang, Y., Soto-Acosta, R., Ding, R., Chen, L. & Geraghty, R. J., Feb 2021, In: Medicinal Chemistry Research. 30, 2, p. 440-448 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Synthesis of macrocyclic α-ketoamide as a selective and reversible immunoproteasome inhibitor
Ding, R., Wilson, D. J. & Chen, L., Feb 2021, In: Medicinal Chemistry Research. 30, 2, p. 410-420 11 p.
Research output: Contribution to journal › Article › peer-review
Discovery of Irreversible p97 Inhibitors
Ding, R., Zhang, T., Wilson, D. J., Xie, J., Williams, J., Xu, Y., Ye, Y. & Chen, L., Mar 14 2019, In: Journal of medicinal chemistry. 62, 5, p. 2814-2829 16 p.
Research output: Contribution to journal › Article › peer-review
7 Scopus citations
UNC-45A is a novel microtubule-associated protein and regulator of paclitaxel sensitivity in ovarian cancer cells
Mooneyham, A., Iizuka, Y., Yang, Q., Coombes, C., McClellan, M., Shridhar, V., Emmings, E., Shetty, M., Chen, L., Ai, T., Meints, J., Lee, M. K., Gardner, M. K. & Bazzaro, M., Feb 2019, In: Molecular Cancer Research. 17, 2, p. 370-383 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
7 Scopus citations
N-(1-Benzyl-3,5-dimethyl‑1H‑pyrazol-4-yl)benzamides: Antiproliferative activity and effects on mTORC1 and autophagy
Ai, T., Willett, R., Williams, J., Ding, R., Wilson, D. J., Xie, J., Kim, D. H., Puertollano, R. & Chen, L., Jan 12 2017, In: ACS Medicinal Chemistry Letters. 8, 1, p. 90-95 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
9 Scopus citations

Optimizing Zika NS5 Methyltransferase Inhibitors

Exploiting SIRT2 for Breast Cancer Therapy

Anti-HCMV activity by an irreversible p97 inhibitor LC-1310

Synthesis of macrocyclic α-ketoamide as a selective and reversible immunoproteasome inhibitor

Discovery of Irreversible p97 Inhibitors

UNC-45A is a novel microtubule-associated protein and regulator of paclitaxel sensitivity in ovarian cancer cells

N-(1-Benzyl-3,5-dimethyl‑1H‑pyrazol-4-yl)benzamides: Antiproliferative activity and effects on mTORC1 and autophagy