20062020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution

Liu, X., Xu, J., Rosenthal, S., Zhang, L. J., McCubbin, R., Meshgin, N., Shang, L., Koyama, Y., Ma, H. Y., Sharma, S., Heinz, S., Glass, C. K., Benner, C., Brenner, D. A. & Kisseleva, T., May 2020, In : Gastroenterology. 158, 6, p. 1728-1744.e14

Research output: Contribution to journalArticle

Open Access

The Underpinnings of PNPLA3-Mediated Fatty Liver Emerge

Shang, L. & Mashek, D. G., Jan 1 2020, In : Hepatology. 71, 1, p. 375-377 3 p.

Research output: Contribution to journalComment/debate

2 Scopus citations
2019

Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity

Foo, K. S., Skowronski, A. A., Baum, D., Firdessa-Fite, R., Thams, S., Shang, L., Creusot, R. J., LeDuc, C. A., Egli, D. & Leibel, R. L., Dec 1 2019, In : Scientific reports. 9, 1, 4965.

Research output: Contribution to journalArticle

Open Access
2018

Human hepatic stellate cell isolation and characterization

Shang, L., Hosseini, M., Liu, X., Kisseleva, T. & Brenner, D. A., Jan 1 2018, In : Journal of Gastroenterology. 53, 1, p. 6-17 12 p.

Research output: Contribution to journalReview article

Open Access
14 Scopus citations
2017

Congenital diaphragmatic hernias: From genes to mechanisms to therapies

Kardon, G., Ackerman, K. G., McCulley, D. J., Shen, Y., Wynn, J., Shang, L., Bogenschutz, E., Sun, X. & Chung, W. K., Aug 1 2017, In : DMM Disease Models and Mechanisms. 10, 8, p. 955-970 16 p.

Research output: Contribution to journalReview article

Open Access
28 Scopus citations
2016

De novo missense variants in PPP2R5D are associated with intellectual disability, macrocephaly, hypotonia, and autism

Shang, L., Henderson, L. B., Cho, M. T., Petrey, D. S., Fong, C. T., Haude, K. M., Shur, N., Lundberg, J., Hauser, N., Carmichael, J., Innis, J., Schuette, J., Wu, Y. W., Asaikar, S., Pearson, M., Folk, L., Retterer, K., Monaghan, K. G. & Chung, W. K., Jan 1 2016, In : Neurogenetics. 17, 1, p. 43-49 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells

Paull, D., Sevilla, A., Zhou, H., Hahn, A. K., Kim, H., Napolitano, C., Tsankov, A., Shang, L., Krumholz, K., Jagadeesan, P., Woodard, C. M., Sun, B., Vilboux, T., Zimmer, M., Forero, E., Moroziewicz, D. N., Martinez, H., Malicdan, M. C. V., Weiss, K. A., Vensand, L. B. & 10 others, Dusenberry, C. R., Polus, H., Sy, K. T. L., Kahler, D. J., Gahl, W. A., Solomon, S. L., Chang, S., Meissner, A., Eggan, K. & Noggle, S. A., Aug 28 2015, In : Nature Methods. 12, 9, p. 885-892 8 p.

Research output: Contribution to journalArticle

98 Scopus citations

Mutations in ARID2 are associated with intellectual disabilities

Shang, L., Cho, M. T., Retterer, K., Folk, L., Humberson, J., Rohena, L., Sidhu, A., Saliganan, S., Iglesias, A., Vitazka, P., Juusola, J., O’Donnell-Luria, A. H., Shen, Y. & Chung, W. K., Oct 26 2015, In : Neurogenetics. 16, 4, p. 307-314 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2014

β-cell dysfunction due to increased ER stress in a stem cell model of wolfram syndrome

Shang, L., Hua, H., Foo, K., Martinez, H., Watanabe, K., Zimmer, M., Kahler, D. J., Freeby, M., Chung, W., LeDuc, C., Goland, R., Leibel, R. L. & Egli, D., Mar 1 2014, In : Diabetes. 63, 3, p. 923-933 11 p.

Research output: Contribution to journalArticle

67 Scopus citations
2013

Engineering bone tissue substitutes from human induced pluripotent stem cells

De Peppo, G. M., Marcos-Campos, I., Kahler, D. J., Alsalman, D., Shang, L., Vunjak-Novakovic, G. & Marolt, D., May 21 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 21, p. 8680-8685 6 p.

Research output: Contribution to journalArticle

133 Scopus citations

Improved Methods for Reprogramming Human Dermal Fibroblasts Using Fluorescence Activated Cell Sorting

Kahler, D. J., Ahmad, F. S., Ritz, A., Hua, H., Moroziewicz, D. N., Sproul, A. A., Dusenberry, C. R., Shang, L., Paull, D., Zimmer, M., Weiss, K. A., Egli, D. & Noggle, S. A., Mar 29 2013, In : PloS one. 8, 3, e59867.

Research output: Contribution to journalArticle

26 Scopus citations

IPSC-derived β cells model diabetes due to glucokinase deficiency

Hua, H., Shang, L., Martinez, H., Freeby, M., Gallagher, M. P., Ludwig, T., Deng, L., Greenberg, E., LeDuc, C., Chung, W. K., Goland, R., Leibel, R. L. & Egli, D., Jul 1 2013, In : Journal of Clinical Investigation. 123, 7, p. 3146-3153 8 p.

Research output: Contribution to journalArticle

64 Scopus citations
2012

Aldose reductase modulates cardiac glycogen synthase kinase-3β phosphorylation during ischemia-reperfusion

Abdillahi, M., Ananthakrishnan, R., Vedantham, S., Shang, L., Zhu, Z., Rosario, R., Zirpoli, H., Bohren, K. M., Gabbay, K. H. & Ramasamy, R., Aug 1 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 303, 3, p. 297-308 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

The Sixth Annual Translational Stem Cell Research Conference of the New York Stem Cell Foundation

Marshall, C., Hua, H., Shang, L., Ding, B. S., Zito, G., de Peppo, G. M., Wang, G. K., Douvaras, P., Sproul, A. A., Paull, D., Fossati, V., Nestor, M. W., Mckeon, D., Smith, K. A. & Solomon, S. L., May 2012, In : Annals of the New York Academy of Sciences. 1255, 1, p. 16-29 14 p.

Research output: Contribution to journalArticle

2010

RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3β signaling pathways

Shang, L., Ananthakrishnan, R., Li, Q., Quadri, N., Abdillahi, M., Zhu, Z., Qu, W., Rosario, R., Touré, F., Yan, S. F., Schmidt, A. M. & Ramasamy, R., Sep 10 2010, In : PloS one. 5, 4, e10092.

Research output: Contribution to journalArticle

61 Scopus citations
2009

Resveratrol augments the canonical Wnt signaling pathway in promoting osteoblastic differentiation of multipotent mesenchymal cells

Zhou, H., Shang, L., Li, X., Zhang, X., Gao, G., Guo, C., Chen, B., Liu, Q., Gong, Y. & Shao, C., Oct 15 2009, In : Experimental Cell Research. 315, 17, p. 2953-2962 10 p.

Research output: Contribution to journalArticle

85 Scopus citations

Serum withdrawal up-regulates human SIRT1 gene expression in a p53-dependent manner

Shang, L., Zhou, H., Xia, Y., Wang, H., Gao, G., Chen, B., Liu, Q., Shao, C. & Gong, Y., Oct 1 2009, In : Journal of Cellular and Molecular Medicine. 13, 10, p. 4176-4184 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2008

Sp1 and CREB regulate basal transcription of the human SNF2L gene

Xia, Y., Jiang, B., Zou, Y., Gao, G., Shang, L., Chen, B., Liu, Q. & Gong, Y., Apr 4 2008, In : Biochemical and Biophysical Research Communications. 368, 2, p. 438-444 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2007

A functional polymorphism in the TIM-1 gene is associated with asthma in a Chinese Han population

Liu, Q., Shang, L., Li, J., Wang, P., Li, H., Wei, C. & Gong, Y., Oct 1 2007, In : International Archives of Allergy and Immunology. 144, 3, p. 197-202 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2006

Gypenosides protect primary cultures of rat cortical cells against oxidative neurotoxicity

Shang, L., Liu, J., Zhu, Q., Zhao, L., Feng, Y., Wang, X., Cao, W. & Xin, H., Aug 2 2006, In : Brain Research. 1102, 1, p. 163-174 12 p.

Research output: Contribution to journalArticle

55 Scopus citations