Linda B von Weymarn

Researcher, Carcinogenesis and Chemoprevention

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Projects 2008 2013

1 Finished

The Collaborative Study of Nicotine Dependence

Murphy, S. E., Hatsukami, D. K. & von Weymarn, L. B.

Washington University St. Louis

7/1/08 → 6/30/13

Project: Research project

nicotine

Research Output 1997 2019

28 Article
1 Comment/debate

Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in human bladder RT4 cells

Bellamri, M., Yao, L., Bonala, R., Johnson, F., von Weymarn, L. B. & Turesky, R., Jul 1 2019, In : Archives of Toxicology. 93, 7, p. 1893-1902 10 p.

Research output: Contribution to journal › Article

Tobacco

Carcinogens

DNA Adducts

Urinary Bladder

Amines

1 Citation (Scopus)

Influence of UGT2B10 Genotype on Urinary Excretion of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol- N- glucuronide by African American Smokers

Murphy, S. E., von Weymarn, L. B., Parenteau, M., Stepanov, I., Tiirikainen, M., Lemarchand, L. & Park, S. L., Mar 19 2018, In : Chemical Research in Toxicology. 31, 3, p. 168-175 8 p.

Research output: Contribution to journal › Article

Open Access

Glucuronides

African Americans

Genotype

Glucuronosyltransferase

Tobacco

2 Citations (Scopus)

In Vivo Stable Isotope Labeling and Mass Spectrometry-Based Metabolic Profiling of a Potent Tobacco-Specific Carcinogen in Rats

Dator, R., von Weymarn, L. B., Villalta, P. W., Hooyman, C. J., Maertens, L. A., Upadhyaya, P., Murphy, S. E. & Balbo, S., Oct 16 2018, In : Analytical Chemistry. 90, 20, p. 11863-11872 10 p.

Research output: Contribution to journal › Article

Tobacco

Metabolites

Isotopes

Carcinogens

Labeling

5 Citations (Scopus)

Nicotine dependence is associated with functional variation in FMO3, an enzyme that metabolizes nicotine in the brain

Teitelbaum, A. M., Murphy, S. E., Akk, G., Baker, T. B., Germann, A., von Weymarn, L. B., Bierut, L. J., Goate, A., Kharasch, E. D. & Bloom, A. J., Jan 1 2018, In : Pharmacogenomics Journal. 18, 1, p. 136-143 8 p.

Research output: Contribution to journal › Article

dimethylaniline monooxygenase (N-oxide forming)

Tobacco Use Disorder

Nicotine

Brain

Enzymes

3 Citations (Scopus)

Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification

Chanickal Narayanapillai, S., von Weymarn, L. B., Carmella, S. G., Leitzman, P., Paladino, J., Upadhyaya, P., Hecht, S. S., Murphy, S. E. & Xing, C., Mar 1 2016, In : Drug Metabolism and Disposition. 44, 3, p. 422-427 6 p.

Research output: Contribution to journal › Article

Lung

Lung Neoplasms

Carcinogenesis

DNA Adducts

4-(methylnitrosamino)-1-(3-pyridyl)-1-butan-1-ol