1992 …2022

Research output per year

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Research Output

2016

EFN-4 functions in LAD-2-mediated axon guidance in Caenorhabditis elegans

Dong, B., Moseley-Alldredge, M., Schwieterman, A. A., Donelson, C. J., McMurry, J. L., Hudson, M. L. & Chen, L., Apr 1 2016, In : Development (Cambridge). 143, 7, p. 1182-1191 10 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Protease inhibitors partially overcome the interferon nonresponse phenotype in patients with chronic hepatitis C

Duarte-Rojo, A., Fischer, S. E., Adeyi, O., Zita, D., Deneke, M. G., Selzner, N., Chen, L., Malespin, M., Cotler, S. J., McGilvray, I. D. & Feld, J. J., May 1 2016, In : Journal of Viral Hepatitis. 23, 5, p. 340-347 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting

Yochem, J., Lažetić, V., Bell, L., Chen, L. & Fay, D., Feb 15 2015, In : Developmental Biology. 398, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014

A novel nondevelopmental role of the sax-7/l1cam cell adhesion molecule in synaptic regulation in caenorhabditis elegans

Opperman, K., Moseley-Alldredge, M., Yochem, J., Bell, L., Kanayinkal, T. & Chen, L., Feb 1 2014, In : Genetics. 199, 2, p. 497-509 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Caenorhabditis elegans reveals a FxNPxY-independent low-density lipoprotein receptor internalization mechanism mediated by epsin1

Kang, Y. L., Yochem, J., Bell, L., Sorensen, E. B., Chen, L. & Conner, S. D., Jan 1 2013, In : Molecular biology of the cell. 24, 3, p. 308-318 11 p.

Research output: Contribution to journalArticle

14 Scopus citations
2011

Neural integrity is maintained by dystrophin in C. elegans

Zhou, S. & Chen, L., Jan 24 2011, In : Journal of Cell Biology. 192, 2, p. 349-363 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

TRPM channels modulate epileptic-like convulsions via systemic ion homeostasis

Stawicki, T. M., Zhou, K., Yochem, J., Chen, L. & Jin, Y., May 24 2011, In : Current Biology. 21, 10, p. 883-888 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
2010

"CRASH"ing with the worm: Insights into L1CAM functions and mechanisms

Chen, L. & Zhou, S., May 1 2010, In : Developmental Dynamics. 239, 5, p. 1490-1501 12 p.

Research output: Contribution to journalReview article

16 Scopus citations
2008

Caenorhabditis elegans models of human neurodegenerative diseases: A powerful tool to identify molecular mechanisms and novel therapeutic targets

Nass, R. & Chen, L., Dec 1 2008, Source Book of Models for Biomedical Research. Humana Press, p. 91-101 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

The C. elegans L1CAM homologue LAD-2 functions as a coreceptor in MAB-20/Sema2-mediated axon guidance

Wang, X., Zhang, W., Cheever, T., Schwarz, V., Opperman, K., Hutter, H., Koepp, D. & Chen, L., Jan 14 2008, In : Journal of Cell Biology. 180, 1, p. 233-246 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

unc-44 ankyrin and stn-2 γ-syntrophin regulate sax-7 L1CAM function in maintaining neuronal positioning in Caenorhabditis elegans

Zhou, S., Opperman, K., Wang, X. & Chen, L., Nov 1 2008, In : Genetics. 180, 3, p. 1429-1443 15 p.

Research output: Contribution to journalArticle

20 Scopus citations
2005

A role for the C. elegans L1CAM homologue lad-1/sax-7 in maintaining tissue attachment

Wang, X., Kweon, J., Larson, S. & Chen, L., Aug 15 2005, In : Developmental Biology. 284, 2, p. 273-291 19 p.

Research output: Contribution to journalArticle

35 Scopus citations
2001

Ankyrins and cellular targeting of diverse membrane proteins to physiological sites

Bennett, V. & Chen, L., Jan 1 2001, In : Current Opinion in Cell Biology. 13, 1, p. 61-67 7 p.

Research output: Contribution to journalReview article

136 Scopus citations
90 Scopus citations
2000

Caenorhabditis elegans β-G spectrin is dispensable for establishment of epithelial polarity, but essential for muscular and neuronal function

Moorthy, S., Chen, L. & Bennett, V., May 15 2000, In : Journal of Cell Biology. 149, 4, p. 915-930 16 p.

Research output: Contribution to journalArticle

83 Scopus citations
1999

Evolutionary conservation of MyoD function and differential utilization of E proteins

Zhang, J. M., Chen, L., Krause, M., Fire, A. & Paterson, B. M., Apr 15 1999, In : Developmental Biology. 208, 2, p. 465-472 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
1994

Elements regulating cell- and stage-specific expression of the C. elegans myod family homolog hlh-1

Krause, M., Harrison, S. W., Xu, S. Q., Chen, L. & Fire, A., Nov 1994, In : Developmental Biology. 166, 1, p. 133-148 16 p.

Research output: Contribution to journalArticle

88 Scopus citations

The caenorhabditis elegans MYOD homologue HLH-1 is essential for proper muscle function and complete morphogenesis

Chen, L., Krause, M., Sepanski, M. & Fire, A., Jun 1 1994, In : Development. 120, 6, p. 1631-1641 11 p.

Research output: Contribution to journalArticle

88 Scopus citations
1992

Body-wall muscle formation in Caenorhabditis elegans embryos that lack the myoD homolog hlh-1

Chen, L., Krause, M., Draper, B., Weintraub, H. & Fire, A., Jan 1 1992, In : Science. 256, 5054, p. 240-243 4 p.

Research output: Contribution to journalArticle

65 Scopus citations