Projects per year
Personal profile
Personal profile
I am associate professor of Genetics, Cell Biology & Development in the University of Minnesota. My research focuses on the genetics of neuropsychiatric disorders and hydrocephalus to understand the mechanisms underlying these conditions.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Interest Keywords
- L1 Syndrome
- Neurological disorders
- Genetics
- neuropsychiatric disorders
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The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A novel approach to restore functional TDP43 for the treatment of FTD and ALS
Sachs, J. N. (PI), Braun, A. R. (CoI), Chen, L. (CoI), Dutton, J. R. (CoI) & Nathan Kochen, N. (Graduate Student)
NIH NATIONAL INSTITUTE ON AGING
5/1/25 → 4/30/27
Project: Research project
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Advanced multiplexing technologies with innovative Dual-Channel Dark-FRET biosensors for dynamic monitoring of alpha-synuclein pathophysiology: From cellular to in vivo models
Sachs, J. N. (PI), Braun, A. R. (Co-Principal Investigator), Chen, L. (Co-Principal Investigator) & Dutton, J. R. (Co-Principal Investigator)
NATIONAL INSTITUTES OF HEALTH (NIH)
7/15/24 → 4/30/26
Project: Research project
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Caenorhabditis Genetics Center
Rougvie, A. E. (PI), Chen, L. (CoI) & Daul, A. L. (CoI)
3/1/22 → 2/28/27
Project: Research project
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L1CAM Adhesion and Signaling Pathways in C. elegans
Chen, L. (PI) & Moseley-Alldredge, M. L. (CoI)
NIH NAT INST OF NEURO DISORDERS & STROKE
2/15/17 → 1/31/24
Project: Research project
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To genetically define the roles of the C. elegans TRPM c
Chen, L. (PI)
12/1/07 → 11/30/09
Project: Research project
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Fluorescence Lifetime-Based FRET Biosensors for Monitoring N Terminal Domain-Dependent Interactions of TDP-43 in Living Cells: A Novel Approach for ALS and FTD Drug Discovery
Nathan Kochen, N., Murray, M., Zafari, S., Vunnam, N., Liao, E. E., Chen, L., Braun, A. R. & Sachs, J. N., Jul 2 2025, In: ACS Chemical Neuroscience. 16, 13, p. 2450-2462 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic etiologies and diagnostic methods for congenital ventriculomegaly and hydrocephalus: A scoping review
Aragón, C., Robinson, D., Kocher, M., Barrick, K., Chen, L. & Zierhut, H., 2023, (Accepted/In press) In: Birth Defects Research. 116, 1, e2287.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
A role for the Erk MAPK pathway in modulating SAX-7/L1CAM-dependent locomotion in Caenorhabditis elegans
Moseley-Alldredge, M., Sheoran, S., Yoo, H., O'Keefe, C., Richmond, J. E. & Chen, L., Feb 2022, In: Genetics. 220, 2, iyab215.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
EFN-4 functions in LAD-2-mediated axon guidance in Caenorhabditis elegans
Dong, B., Moseley-Alldredge, M., Schwieterman, A. A., Donelson, C. J., McMurry, J. L., Hudson, M. L. & Chen, L., Apr 1 2016, In: Development (Cambridge). 143, 7, p. 1182-1191 10 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting
Yochem, J., Lažetić, V., Bell, L., Chen, L. & Fay, D., Feb 15 2015, In: Developmental Biology. 398, 2, p. 255-266 12 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations