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Personal profile

Personal profile

I am associate professor of Genetics, Cell Biology & Development in the University of Minnesota.  My research focuses on the genetics of neuropsychiatric disorders and hydrocephalus to understand the mechanisms underlying these conditions. 

Research interests

  • L1 Syndrome
  • Neurological disorders
  • Genetics
  • neuropsychiatric disorders

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects 2005 2022

Neural Cell Adhesion Molecule L1
Neural Cell Adhesion Molecule L1

Research Output 1992 2016

3 Citations (Scopus)

EFN-4 functions in LAD-2-mediated axon guidance in Caenorhabditis elegans

Dong, B., Moseley-Alldredge, M., Schwieterman, A. A., Donelson, C. J., McMurry, J. L., Hudson, M. L. & Chen, L., Apr 1 2016, In : Development (Cambridge). 143, 7, p. 1182-1191 10 p.

Research output: Contribution to journalArticle

Ephrins
Caenorhabditis elegans
nervous system
adhesion
navigation
1 Citation (Scopus)

Protease inhibitors partially overcome the interferon nonresponse phenotype in patients with chronic hepatitis C

Duarte-Rojo, A., Fischer, S. E., Adeyi, O., Zita, D., Deneke, M. G., Selzner, N., Chen, L., Malespin, M., Cotler, S. J., McGilvray, I. D. & Feld, J. J., May 1 2016, In : Journal of Viral Hepatitis. 23, 5, p. 340-347 8 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Protease Inhibitors
Interferons
Orthomyxoviridae
Phenotype
6 Citations (Scopus)

C. elegans NIMA-related kinases NEKL-2 and NEKL-3 are required for the completion of molting

Yochem, J., Lažetić, V., Bell, L., Chen, L. & Fay, D., Feb 15 2015, In : Developmental Biology. 398, 2, p. 255-266 12 p.

Research output: Contribution to journalArticle

Molting
Low Density Lipoprotein Receptor-Related Protein-2
Body Regions
Mutation
Endosomes
3 Citations (Scopus)

A novel nondevelopmental role of the sax-7/l1cam cell adhesion molecule in synaptic regulation in caenorhabditis elegans

Opperman, K., Moseley-Alldredge, M., Yochem, J., Bell, L., Kanayinkal, T. & Chen, L., Feb 1 2014, In : Genetics. 199, 2, p. 497-509 13 p.

Research output: Contribution to journalArticle

Neural Cell Adhesion Molecule L1
Caenorhabditis elegans
Cell Adhesion Molecules
Nervous System
Autistic Disorder
13 Citations (Scopus)

Caenorhabditis elegans reveals a FxNPxY-independent low-density lipoprotein receptor internalization mechanism mediated by epsin1

Kang, Y. L., Yochem, J., Bell, L., Sorensen, E. B., Chen, L. & Conner, S. D., Jan 1 2013, In : Molecular biology of the cell. 24, 3, p. 308-318 11 p.

Research output: Contribution to journalArticle

LDL Receptors
Caenorhabditis elegans
Endocytosis
Clathrin
Ubiquitination