20002018

Research output per year

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Research Output

Article

Amyloid β peptide load is correlated with increased β-secretase activity in sporadic Alzheimer's disease patients

Li, R., Lindholm, K., Yang, L. B., Yue, X., Citron, M., Yan, R., Beach, T., Sue, L., Sebbagh, M., Cai, H., Wong, P., Price, D. & Shen, Y., Mar 9 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 10, p. 3632-3637 6 p.

Research output: Contribution to journalArticle

392 Scopus citations
Open Access
19 Scopus citations

Complement activation by neurofibrillary tangles in Alzheimer's disease

Shen, Y., Lue, L. F., Yang, L., Roher, A., Kuo, Y. M., Strohmeyer, R., Goux, W. J., Lee, V., Johnson, G. V. W., Webster, S. D., Cooper, N. R., Bradt, B. & Rogers, J., Jun 15 2001, In : Neuroscience Letters. 305, 3, p. 165-168 4 p.

Research output: Contribution to journalArticle

115 Scopus citations

Deficiency of complement defense protein CD59 may contribute to neurodegeneration in Alzheimer's disease

Yang, L. B., Li, R., Meri, S., Rogers, J. & Shen, Y., Oct 15 2000, In : Journal of Neuroscience. 20, 20, p. 7505-7509 5 p.

Research output: Contribution to journalArticle

96 Scopus citations

Deficiency of GDNF receptor GFRα1 in Alzheimer's neurons results in neuronal death

Konishi, Y., Yang, L., He, P., Lindholm, K., Lu, B., Li, R. & Shen, Y., Sep 24 2014, In : Journal of Neuroscience. 34, 39, p. 13127-13138 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients

Cheng, X., Yang, L., He, P., Li, R. & Shen, Y., 2010, In : Journal of Alzheimer's Disease. 19, 2, p. 621-630 10 p.

Research output: Contribution to journalArticle

59 Scopus citations

Differentiation of human induced-pluripotent stem cells into smooth-muscle cells: Two novel protocols

Yang, L., Geng, Z., Nickel, T., Johnson, C., Gao, L., Dutton, J. R., Hou, C. & Zhang, J. J., Jan 1 2016, In : PloS one. 11, 1, 0147155.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Estrogen enhances uptake of amyloid β-protein by microglia derived from the human cortex

Li, R., Shen, Y., Yang, L. B., Lue, L. F., Finch, C. & Rogers, J., Sep 26 2000, In : Journal of Neurochemistry. 75, 4, p. 1447-1454 8 p.

Research output: Contribution to journalArticle

127 Scopus citations
Open Access
10 Scopus citations

Induction of tumorigenesis and metastasis by the murine orthologue of tumor protein D52

Lewis, J. D., Payton, L. A., Whitford, J. G., Byrne, J. A., Smith, D. I., Yang, L. B. & Bright, R. K., Feb 1 2007, In : Molecular Cancer Research. 5, 2, p. 133-144 12 p.

Research output: Contribution to journalArticle

48 Scopus citations

Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro

Lue, L. F., Rydel, R., Brigham, E. F., Yang, L. B., Hampel, H., Murphy, G. M., Brachova, L., Yan, S. D., Walker, D. G., Shen, Y. & Rogers, J., Jul 30 2001, In : Glia. 35, 1, p. 72-79 8 p.

Research output: Contribution to journalArticle

278 Scopus citations

Isolation of living neurons from human elderly brains using the immunomagnetic sorting DNA-linker system

Konishi, Y., Lindholm, K., Yang, L. B., Li, R. & Shen, Y., Jan 1 2002, In : American Journal of Pathology. 161, 5, p. 1567-1576 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Lactate promotes synthetic phenotype in vascular smooth muscle cells

Yang, L., Gao, L., Nickel, T., Yang, J., Zhou, J., Gilbertsen, A. J., Geng, Z., Johnson, C., Young, B., Henke, C. A., Gourley, G. R. & Zhang, J., Jan 1 2017, In : Circulation research. 121, 11, p. 1251-1262 12 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

Myocardial Tissue Engineering with Cells Derived from Human-Induced Pluripotent Stem Cells and a Native-Like, High-Resolution, 3-Dimensionally Printed Scaffold

Gao, L., Kupfer, M. E., Jung, J. P., Yang, L., Zhang, P., Da Sie, Y., Tran, Q., Ajeti, V., Freeman, B. T., Fast, V. G., Campagnola, P. J., Ogle, B. M. & Zhang, J., Apr 14 2017, In : Circulation research. 120, 8, p. 1318-1325 8 p.

Research output: Contribution to journalArticle

Open Access
92 Scopus citations

Novel biomarker candidates to predict hepatic fibrosis in hepatitis C identified by serum proteomics

Yang, L., Rudser, K. D., Higgins, L., Rosen, H. R., Zaman, A., Corless, C. L., David, L. & Gourley, G. R., Nov 1 2011, In : Digestive Diseases and Sciences. 56, 11, p. 3305-3315 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Proteomic analysis of biopsied human colonic mucosa

Gourley, G. R., Yang, L., Higgins, L., Riviere, M. A. & David, L. L., Jul 1 2010, In : Journal of pediatric gastroenterology and nutrition. 51, 1, p. 46-54 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Quantitative Proteomics and Immunohistochemistry Reveal Insights into Cellular and Molecular Processes in the Infarct Border Zone One Month after Myocardial Infarction

Yang, L., Gregorich, Z. R., Cai, W., Zhang, P., Young, B., Gu, Y., Zhang, J. J. & Ge, Y., May 5 2017, In : Journal of Proteome Research. 16, 5, p. 2101-2112 12 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Relationship between the efficacy of cardiac cell therapy and the inhibition of differentiation of human iPSC-Derived nonmyocyte cardiac cells into Myofibroblast-like cells

Gao, L., Yang, L., Wang, L., Geng, Z., Wei, Y., Gourley, G. & Zhang, J., Jan 1 2018, In : Circulation research. 123, 12, p. 1313-1325 13 p.

Research output: Contribution to journalArticle

Open Access

Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways

Yang, L., Lindholm, K., Konishi, Y., Li, R. & Shen, Y., Apr 15 2002, In : Journal of Neuroscience. 22, 8, p. 3025-3032 8 p.

Research output: Contribution to journalArticle

196 Scopus citations

Tumor Necrosis Factor Death Receptor Signaling Cascade Is Required for Amyloid-β Protein-Induced Neuron Death

Li, R., Yang, L., Lindholm, K., Konishi, Y., Yue, X., Hampel, H., Zhang, D. & Shen, Y., Feb 18 2004, In : Journal of Neuroscience. 24, 7, p. 1760-1771 12 p.

Research output: Contribution to journalArticle

146 Scopus citations

What does complement do in Alzheimer's disease? Old molecules with new insights

Shen, Y., Yang, L. & Li, R., Oct 12 2013, In : Translational Neurodegeneration. 2, 1, 21.

Research output: Contribution to journalArticle

30 Scopus citations
Letter

Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease [1]

Yang, L. B., Lindholm, K., Yan, R., Citron, M., Xia, W., Yang, X. L., Beach, T., Sue, L., Wong, P., Price, D., Li, R. & Shen, Y., Jan 1 2003, In : Nature Medicine. 9, 1, p. 3-4 2 p.

Research output: Contribution to journalLetter

522 Scopus citations
Review article

Inflammatory mediators in the Alzheimer's disease brain

Rogers, J., Yang, L. B., Lue, L. F., Strohmeyer, R., Liang, Z., Konishi, Y., Li, R., Walker, D. & Shen, Y., Jan 1 2000, In : NeuroScience News. 3, 4, p. 38-45 8 p.

Research output: Contribution to journalReview article

2 Scopus citations