Li Ou

Personal profile

Education/Academic qualification

University of Minnesota

Sep 1 2011 → Jun 12 2015

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

22 Similar Profiles

Mucopolysaccharidosis I Medicine & Life Sciences

Iduronidase Medicine & Life Sciences

Mucopolysaccharidoses Medicine & Life Sciences

GM1 Gangliosidosis Medicine & Life Sciences

Genetic Association Studies Medicine & Life Sciences

Glycosaminoglycans Medicine & Life Sciences

Neurology Chemical Compounds

Mucopolysaccharidosis IV Medicine & Life Sciences

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Projects 2019 2020

1 Active

Pilot Study of AGT-m195 in GLB1 Knockout Mouse Model of GM1-Gangliosidosis

Whitley, C. B. & Ou, L.

TANABE RESEARCH LABS USA INC.

4/1/19 → 5/31/20

Project: Research project

GM1 Gangliosidosis

Knockout Mice

Research Output 2010 2019

15 Article
1 Chapter

A longitudinal study of neurocognition and behavior in patients with Hurler-Scheie syndrome heterozygous for the L238Q mutation

Ahmed, A., Ou, L., Rudser, K., Shapiro, E., Eisengart, J., King, K. E., Chen, A., Dickson, P. & Whitley, C. B., Sep 2019, In : Molecular Genetics and Metabolism Reports. 20, 100484.

Research output: Contribution to journal › Article

Open Access

Mucopolysaccharidosis I

Longitudinal Studies

Iduronidase

Mutation

Computational Biology

2 Citations (Scopus)

Comprehensive behavioral and biochemical outcomes of novel murine models of GM1-gangliosidosis and Morquio syndrome type B

Przybilla, M. J., Ou, L., Tăbăran, A. F., Jiang, X., Sidhu, R., Kell, P. J., Ory, D. S., O'Sullivan, M. G. & Whitley, C. B., Feb 2019, In : Molecular Genetics and Metabolism. 126, 2, p. 139-150 12 p.

Research output: Contribution to journal › Article

Mucopolysaccharidosis IV

GM1 Gangliosidosis

Enzyme activity

Galactosidases

Clustered Regularly Interspaced Short Palindromic Repeats

Genotype-phenotype correlation of gangliosidosis mutations using in silico tools and homology modeling

Ou, L., Kim, S., Whitley, C. B. & Jarnes-Utz, J. R., Sep 2019, In : Molecular Genetics and Metabolism Reports. 20, 100495.

Research output: Contribution to journal › Article

Open Access

Gangliosidoses

Genetic Association Studies

Computer Simulation

GM2 Gangliosidosis

Mutation

5 Citations (Scopus)

Metabolomics profiling reveals profound metabolic impairments in mice and patients with Sandhoff disease

Ou, L., Przybilla, M. & Whitley, C. B., Feb 1 2019, In : Molecular Genetics and Metabolism. 126, 2, p. 151-156 6 p.

Research output: Contribution to journal › Article

Open Access

Sandhoff Disease

Metabolomics

Metabolites

Biomarkers

G(M2) Ganglioside

4 Citations (Scopus)

ZFN-Mediated In Vivo Genome Editing Corrects Murine Hurler Syndrome

Ou, L., DeKelver, R. C., Rohde, M., Tom, S., Radeke, R., St. Martin, S. J., Santiago, Y., Sproul, S., Przybilla, M., Koniar, B. L., Podetz-Pedersen, K. M., Laoharawee, K., Cooksley, R. D., Meyer, K. E., Holmes, M. C., Mc Ivor, R. S., Wechsler, T. & Whitley, C. B., Jan 2 2019, In : Molecular Therapy. 27, 1, p. 178-187 10 p.

Research output: Contribution to journal › Article

Open Access

Mucopolysaccharidosis I

Clinical Trials

Genome

Injections

Gene Editing