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PhD projects

Blood-brain transport and drug delivery to the brain

1973 …2020

Research output per year

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Personal profile

Research interests

  • blood-brain transport
  • brain endothelium
  • neurovascular unit
  • Brain energy metabolism
  • Blood-brain barrier genomics
  • drug delivery to CNS
  • transporter inhibitors as anticancer agents
  • cerebral anoxia, ischemia
  • Re-engineering the blood-brain barrier

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Projects

  • Research Output

    A novel MCT1 and MCT4 dual inhibitor reduces mitochondrial metabolism and inhibits tumour growth of feline oral squamous cell carcinoma

    Khammanivong, A., Saha, J., Spartz, A. K., Sorenson, B. S., Bush, A. G., Korpela, D. M., Gopalakrishnan, R., Jonnalagadda, S., Mereddy, V. R., O'Brien, T. D., Drewes, L. R. & Dickerson, E. B., Jan 1 2019, (Accepted/In press) In : Veterinary and Comparative Oncology.

    Research output: Contribution to journalArticle

  • Development and radiosynthesis of the first 18F-labeled inhibitor of monocarboxylate transporters (MCTs)

    Sadeghzadeh, M., Moldovan, R. P., Fischer, S., Wenzel, B., Ludwig, F. A., Teodoro, R., Deuther-Conrad, W., Jonnalagadda, S., Jonnalagadda, S. K., Gudelis, E., Šačkus, A., Higuchi, K., Ganapathy, V., Mereddy, V. R., Drewes, L. R. & Brust, P., Jun 30 2019, In : Journal of Labelled Compounds and Radiopharmaceuticals. 62, 8, p. 411-424 14 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Development of Novel Silyl Cyanocinnamic Acid Derivatives as Metabolic Plasticity Inhibitors for Cancer Treatment

    Nelson, G. L., Ronayne, C. T., Solano, L. N., Jonnalagadda, S. K., Jonnalagadda, S., Rumbley, J., Holy, J., Rose-Hellekant, T., Drewes, L. R. & Mereddy, V. R., Dec 1 2019, In : Scientific reports. 9, 1, 18266.

    Research output: Contribution to journalArticle

    Open Access
  • Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors

    Jonnalagadda, S., Jonnalagadda, S. K., Ronayne, C. T., Nelson, G. L., Solano, L. N., Rumbley, J. N., Holy, J. M., Mereddy, V. R. & Drewes, L. R., Mar 22 2019, In : Oncotarget. 10, 24, p. 2355-2368 14 p.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    The year in review: Progress in brain barriers and brain fluid research in 2018

    Keep, R. F., Jones, H. C. & Drewes, L. R., Feb 5 2019, In : Fluids and Barriers of the CNS. 16, 1, 4.

    Research output: Contribution to journalReview article

    Open Access
  • 1 Scopus citations