1973 …2019
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Personal profile

Research interests

  • blood-brain transport
  • brain endothelium
  • neurovascular unit
  • Brain energy metabolism
  • Blood-brain barrier genomics
  • drug delivery to CNS
  • transporter inhibitors as anticancer agents
  • cerebral anoxia, ischemia
  • Re-engineering the blood-brain barrier

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

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Brain Medicine & Life Sciences
Facilitative Glucose Transport Proteins Medicine & Life Sciences
Canidae Medicine & Life Sciences
Blood-Brain Barrier Medicine & Life Sciences
Microvessels Medicine & Life Sciences
Endothelial Cells Medicine & Life Sciences
Monocarboxylic Acid Transporters Medicine & Life Sciences
Glucose Medicine & Life Sciences

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Projects 2000 2019

Mouth Neoplasms
Energy Metabolism
Muscle Fatigue
Skeletal Muscle
Triple Negative Breast Neoplasms
Pharmaceutical Preparations

Research Output 1973 2019

1 Citation (Scopus)

Development and radiosynthesis of the first 18F-labeled inhibitor of monocarboxylate transporters (MCTs)

Sadeghzadeh, M., Moldovan, R. P., Fischer, S., Wenzel, B., Ludwig, F. A., Teodoro, R., Deuther-Conrad, W., Jonnalagadda, S., Jonnalagadda, S. K., Gudelis, E., Šačkus, A., Higuchi, K., Ganapathy, V., Mereddy, V. R., Drewes, L. R. & Brust, P., Jun 30 2019, In : Journal of Labelled Compounds and Radiopharmaceuticals. 62, 8, p. 411-424 14 p.

Research output: Contribution to journalArticle

Imaging techniques
4-coumaric acid

Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors

Jonnalagadda, S., Jonnalagadda, S. K., Ronayne, C. T., Nelson, G. L., Solano, L. N., Rumbley, J. N., Holy, J. M., Mereddy, V. R. & Drewes, L. R., Mar 22 2019, In : Oncotarget. 10, 24, p. 2355-2368 14 p.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Exercise Test
1 Citation (Scopus)

The year in review: Progress in brain barriers and brain fluid research in 2018

Keep, R. F., Jones, H. C. & Drewes, L. R., Feb 5 2019, In : Fluids and Barriers of the CNS. 16, 1, 4.

Research output: Contribution to journalReview article

Open Access
Brain Diseases
Pharmaceutical Preparations
26 Citations (Scopus)

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, Markus, H. S., Salman, R. A., Allan, S. M., Quinn, T. J., Kalaria, R. N., Werring, D. J., Carare, R. O., Touyz, R. M., Williams, S. C. R., Moskowitz, M. A., Katusic, Z. S., Lutz, S. E., Lazarov, O., Minshall, R. D., Rehman, J., Davis, T. P., Wellington, C. L., González, H. M., Yuan, C., Lockhart, S. N., Hughes, T. M., Chen, C. L. H., Sachdev, P., O'Brien, J. T., Skoog, I., Pantoni, L., Gustafson, D. R., Biessels, G. J., Wallin, A., Smith, E. E., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, M. M. B., Román, G. C., Hamel, E., Seshadri, S., Gottesman, R. F., van Buchem, M. A., Arvanitakis, Z., Schneider, J. A., Drewes, L. R., Hachinski, V., Finch, C. E., Toga, A. W., Wardlaw, J. M. & Zlokovic, B. V., Jan 2019, In : Alzheimer's and Dementia. 15, 1, p. 158-167 10 p.

Research output: Contribution to journalShort survey

Open Access
Blood Vessels
Alzheimer Disease
Cerebrovascular Circulation
Brain Diseases
9 Citations (Scopus)

mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction

Liu, D., Stowie, A., de Zavalia, N., Leise, T., Pathak, S. S., Drewes, L. R., Davidson, A. J., Amir, S., Sonenberg, N. & Cao, R., Apr 3 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 14, p. E3296-E3304

Research output: Contribution to journalArticle

Open Access
Circadian Clocks
Suprachiasmatic Nucleus