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Personal profile

Education/Academic qualification

PhD, Duke University

BS, Wake Forest University

Fingerprint The Fingerprint is created by mining the titles and abstracts of the person's research outputs and projects/funding awards to create an index of weighted terms from discipline-specific thesauri.

  • 3 Similar Profiles
Peptide Synthases Medicine & Life Sciences
Francisella Medicine & Life Sciences
Biofilms Medicine & Life Sciences
Phosphites Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Acinetobacter baumannii Medicine & Life Sciences
Hydroxyurea Medicine & Life Sciences
Anti-Bacterial Agents Medicine & Life Sciences

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Research Output 2005 2020

N-butyldeoxygalactonojirimycin induces reversible infertility in male CD rats

Gupta, V., Hild, S. A., Jakkaraj, S. R., Carlson, E. J., Wong, H. L., Allen, C. L., Georg, G. & Tash, J. S., Jan 1 2020, In : International Journal of Molecular Sciences. 21, 1, 301.

Research output: Contribution to journalArticle

Open Access
Male Infertility
ceramide glucosyltransferase
rats
Rats
Ceramides

Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections

Draughn, G. L., Allen, C. L., Routh, P. A., Stone, M. R., Kirker, K. R., Boegli, L., Schuchman, R. M., Linder, K. E., Baynes, R. E., James, G., Melander, C., Pollard, A. & Cavanagh, J., Jan 11 2017, In : Drug Design, Development and Therapy. 2017, 11, p. 153-162

Research output: Contribution to journalArticle

Open Access
File
Bacterial Infections
Biofilms
Skin
Anti-Bacterial Agents
Bacteria
7 Citations (Scopus)

Structure of the Francisella response regulator QseB receiver domain, and characterization of QseB inhibition by antibiofilm 2-aminoimidazole-based compounds: Inhibition of response regulator QseB by antibiofilm compounds

Milton, M. E., Leigh Allen, C., Feldmann, E. A., Bobay, B. G., Jung, D. K., Stephens, M. D., Melander, R. J., Theisen, K. E., Zeng, D., Thompson, R. J., Melander, C. & Cavanagh, J., Aug 16 2017, In : Molecular Microbiology.

Research output: Contribution to journalArticle

Open Access
Francisella
Francisella tularensis
Anti-Bacterial Agents
Bacteria
Virulence Factors
93 Citations (Scopus)

Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

Drake, E. J., Miller, B. R., Shi, C., Tarrasch, J. T., Sundlov, J. A., Allen, L., Skiniotis, G., Aldrich, C. C. & Gulick, A. M., Jan 13 2016, In : Nature. 529, 7585, p. 235-238 4 p.

Research output: Contribution to journalArticle

Peptide Synthases
Bioengineering
Biological Products
Catalysis
Catalytic Domain
10 Citations (Scopus)

The role of phosphate in a multistep enzymatic reaction: Reactions of the substrate and intermediate in pieces

Kholodar, S. A., Allen, C. L., Gulick, A. M. & Murkin, A. S., Feb 25 2015, In : Journal of the American Chemical Society. 137, 7, p. 2748-2756 9 p.

Research output: Contribution to journalArticle

Phosphites
Phosphates
Isomerization
Substrates
Enzymes